NBRP Rat No: 0280 Strain NameDA-Tg(CAG-lacZ)30Jmsk Commmon Name: LacZ30
 Principal Investigator  Eiji Kobayashi
 Organization   Center for Molecular Medicine, Jichi Medical School Division of Organ Replacement Research
 Address  3311-1, Yakushiji, Shimono-shi, Tochigi

329-0498 Tochigi

 Telephone  0285-58-7446  Fax:  0285-44-5365  eijikoba@jichi.ac.jp
 Inbred Generations    
 Coat Color
 Deposition Status
  Embryo      Sperm      Live Animals
 Usage Restrictions  The recipient is requested to cite in the following literature designated by the DEPOSITOR. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene lacZ: beta-galactosidase, E. coli
 Origin This strain was established at Jichi Medical School. 
 Strain Characteristics This transgenic strain expresses LacZ gene ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscle. The strain NBRP No.0280 (line30) is more strongly stained by X-gal staining. 
 Breeding Conditions Good breeding performance. 
 References  Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E.
Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardium.
Biochem Biophys Res Commun. 2003 Jun 13;305(4):904-8.

Takahashi M, Hakamata Y, Takeuchi K, Kobayashi E.
Effects of different fixatives on beta-galactosidase activity.
J Histochem Cytochem. 2003 Apr;51(4):553-4.