Japanese
 NBRP Rat No: 0371 Strain Name: W-Tg(S100b-EGFP)Scell Commmon Name: Wistar-Tg(S100b-EGFP)Scell, Wistar-<i>Tg(S100b-GFP)Scell</i>,&nbsp;s100b-GFP
 Principal Investigator  Kinji Inoue
 Organization   Faculty of Science, Saitama University Laboratory of Cell Biology
 Address  255 Shimo-ohkubo Sakura-ku Saitama

338-8570 Saitama

  Japan
 Telephone  048‐858-3422  Fax:  048‐858-3422  kininoue@mail.saitama-u.ac.jp
 Inbred Generations   F?+8 (April 2012) 
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions   In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing, an acknowledgment to the DEPOSITOR is requested.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene S100b, GFP: Green Fluorescent Protein, jellyfish
 Origin  
 Strain Characteristics This transgenic rats expressed GFP in FS cells specifically in the anterior lobe. GFP is also expressed in other known S-100β expressing cells, i.e., brain astrocytes, adipocytes and chondrocytes. 
 Breeding Conditions Homozygous rats have difficulty in breeding.
Mating between heterozygous and wild-type rats.  
 Genotyping <a href="http://www.anim.med.kyoto-u.ac.jp/nbr/documents/PCR_Gene/S100β-EGFP_en.pdf">Genotyping protocol for S100β-EGFP</a>
 
 References  Gallucci A, Patterson KC, Weit AR, Van Der Pol WJ, Dubois LG, Percy AK, Morrow CD, Campbell SL, Olsen ML.
Microbial community changes in a female rat model of Rett syndrome.
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13:109:110259.

Syaidah R, Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kikuchi M, Yashiro T.
Fibromodulin Expression in Folliculostellate Cells and Pericytes Is Promoted by TGFβ Signaling in Rat Anterior Pituitary Gland.
Acta Histochem Cytochem.2016 Dec 28; 49 (6): 171&#8211;179.

Patterson KC, Hawkins VE, Arps KM, Mulkey DK, Olsen ML.
MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats.
Hum Mol Genet. 2016 Aug 1;25(15):3303-3320.

Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K.
Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes.
Endocrinology. 2007 Apr;148(4):1518-23.