NBRP Rat No: 0371 Strain NameW-Tg(S100b-EGFP)Scell Commmon Name: Wistar-Tg(S100b-EGFP)Scell, Wistar-<i>Tg(S100b-GFP)Scell</i>,&nbsp;s100b-GFP
 Principal Investigator  Kinji Inoue
 Organization   Faculty of Science, Saitama University Laboratory of Cell Biology
 Address  255 Shimo-ohkubo Sakura-ku Saitama

338-8570 Saitama

 Telephone  048‐858-3422  Fax:  048‐858-3422  kininoue@mail.saitama-u.ac.jp
 Inbred Generations   F?+8 (April 2012) 
 Coat Color
 Deposition Status
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions   In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing, an acknowledgment to the DEPOSITOR is requested.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene S100b, GFP: Green Fluorescent Protein, jellyfish
 Strain Characteristics This transgenic rats expressed GFP in FS cells specifically in the anterior lobe. GFP is also expressed in other known S-100β expressing cells, i.e., brain astrocytes, adipocytes and chondrocytes. 
 Breeding Conditions Transgene dose not affect their breeding. 
 Genotyping <a href="http://www.anim.med.kyoto-u.ac.jp/nbr/documents/PCR_Gene/S100β-EGFP_en.pdf">Genotyping protocol for S100β-EGFP</a>
 References  Syaidah R, Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kikuchi M, Yashiro T.
Fibromodulin Expression in Folliculostellate Cells and Pericytes Is Promoted by TGFβ Signaling in Rat Anterior Pituitary Gland.
Acta Histochem Cytochem.2016 Dec 28; 49 (6): 171&#8211;179.

Patterson KC, Hawkins VE, Arps KM, Mulkey DK, Olsen ML.
MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats.
Hum Mol Genet. 2016 Aug 1;25(15):3303-3320.

Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K.
Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes.
Endocrinology. 2007 Apr;148(4):1518-23.