| 維持機関: |
Yan Y, Zeng ZZ, Higashi S, Denda A, Konishi Y, Onishi S, Ueno H, Higashi K, Hiai H.
Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage.
Carcinogenesis. 2002 Jan;23:189-96.
Hamada S, Yamasaki KI, Nakanishi S, Omori T, Serikawa T, Hayashi M.
Evaluation of the general suitability of the rat for the micronucleus assay: the effect of cyclophosphamide in 14 strains.
Mutat Res. 2001 Aug 22;495:127-34.
Hirano T, Higashi K, Sakai A, Tsurutome Y, Ootsumura Y, Kido R & Kasai H
Analyses of oxidative DNA damage and its repair activity in the livers of 3'-methyl-4-dimethylaminoazobenzene-treated rodents.
Jpn.J.Cancer Res.91:681-685, 2000
Todaka N, Higashi K, Abe T, Yamashiro K & Hiai H
Investigation of possible involvement of several genes related to development of hepatocarcinogenesis in rats.
J Univ Occup Environm Health 22: ll9-l32, 2000
Zeng ZZ, Higashi S, Kitayama W, Denda A, Yan Y, Matsuo K, Konishi Y, Hiai H, Higashi K.
Genetic resistance to chemical carcinogen-induced preneoplastic hepatic lesions in DRH strain rats.
Cancer Res. 2000 Jun 1;60:2876-81.
Yamashiro K, Yan Y, Fukamachi Y, Gotoh S, Higashi K, Ohtsuki M, Hamada Y, Higashi T.
Blunt cell growth potential in carcinogen resistant inbred DRH rats.
Exp Anim. 2000 Jan;49:47-50. |
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Yoshimoto F, Masuda S, Higashi T, Nishii T, Takamisawa I, Tateishi N, & Sakamoto Y
Comparison of drug-metabolizing activities in the livers of carcinogen-sensitive parent and carcinogen-resistant descendants.
Cancer Res 45: 6155-6159, 1985
Higashi T, Fukui R, Sekiyama M, Yoshimoto F, Tateishi N & Sakamoto Y
Decreased induction of gamma-glutamyltranspeptidase activity by 3'-methyl-4-dimethylaminoazobenzene in the liver of rats given carcinogen-containing diet for several generations.
Jpn J Cancer Res 77: 139-144, 1986
Yano M, Higashi T, Kano S, Tateishi N, Kido Y, Mori T, Higashi K, & Sakamoto Y
Decreased activation of carcinogens in the liver of carcinogen-resistant rats.
Cancer Res 49:5352-5357, 1989
Masuda S
Mechanism of resistance to hepatocarcinogenic action of 3'-methyl-4-dimethylaminoazobenzene in genetically carcinogen-resistant rats.
Med J Osaka Univ 42:103-117, 1990. (in Japanese, abstract in English).
Hamada H, Higashi T, Tateishi N, Hanatani M & Sakamoto Y
Lipid peroxidation in the liver of carcinogen-resistant rats.
Biochim Biophys Acta 1045: 99-106, 1990
Yan Y, Higashi K, Yamamura K, Fukamachi Y, Abe T, Gotoh S, Sugiura T, Higashi T, & Ichiba M
Different responses other than the formation of DNA-adducts between the livers of carcinogen-resistant rats (DRH) and carcinogen-sensitive rats (Donryu) to 3'-methyl-4-dimethylaminoazobenzene administration.
Jpn J Cancer Res 89: 806-813, 1998
Yan Y, Higashi K, Tanimoto A, Fukamachi Y, Itoh H, Abe T & Higashi T
Remarkable difference in the incidence of liver tumors by N-nitrosodimethylamine in carcinogen-resistant DRH rat and its parental strain Donryu rat.
J Univ Occup Environm Health 20: 307-314, 1998
Denda A, Kitayama W, Konishi Y, Yan Y, Fukamachi Y, Miura M, Gotoh S, Ikemura K, Abe T, Higashi T & Higashi K
Genetic properties for the suppression of development of putative preneoplastic glutathione S-transferase placental form-positive foci in the liver of carcinogen-resistant DRH strain rats.
Cancer Let 140: 59-67, 1999
Yan Y, Todaka N, Yamamura K, Hirano H, Gotoh S, Katoh T, Higashi K, Arai S, Murata Y, Higashi T & Jirtle R L
The occurence of polymorphism of mannose 6-phosphate/insulin like growth factor 2 receptor gene in laboratory and wild rats.
J Univ Occup Environm Health 21: 199-208, 1999
Goth S, Todaka N, Yan Y, Fukamachi Y, Abe T & Higashi K
Studies on the multidrug resistance gene expression in the livers of rats associated with different susceptibility of hepatocarcinogenesis.
J Univ Occup Environm Health 21: 265-276, 1999
Mise-Omata S, Sugiura T, Higashi K & Yamashita U
Reduced T cell response in carcinogen-sensitive Donryu rats compared with carcinogen-resistant DRH rats.
Jpn J Cancer Res 90: 1277-1284, 1999
Yamashiro K, Yan Y, Fukamachi Y, Gotoh S, Higashi K, Ohtsuki M, Hamada Y & Higashi T
Blunt cell growth potential in carcinogen resistant inbred DRH rats.
Exp Anim 49: 47-50, 2000
Zeng Z-Z, Higashi S, Kitayama W, Denda A, Yan Y, Matsuo K, Konishi Y, Hiai H & Higashi K
Genetic resistance to chemical carcinogen-induced preneoplastic hepatic lesions in DRH strain rats.
Cancer Res.60: 2876-2881, 2000
Todaka N, Higashi K, Abe T, Yamashiro K & Hiai H
Investigation of possible involvement of several genes related to development of hepatocarcinogenesis in rats.
J Univ Occup Environm Health 22: ll9-l32, 2000
Hirano T, Higashi K, Sakai A, Tsurutome Y, Ootsumura Y, Kido R & Kasai H
Analyses of oxidative DNA damage and its repair activity in the livers of 3'-methyl-4-dimethylaminoazobenzene-treated rodents.
Jpn.J.Cancer Res.91:681-685, 2000
Ying Yan, Zhao-Zhu Zeng, Shin Higashi, Ayumi Zenda, Yoichi Konishi, Shunzo Onishi, Hiraku Ueno, Ken Higashi, and Hiroshi Hiai
Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage.
Carcinogenesis 23:189-196, 2002
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