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Yoshida, M. C., Masuda, R., Sasaki, M., Takeichi, N., Kobayashi, H., Dempo, K., Mori, M.
New mutation causing hereditary hepatitis in the laboratory rat.
J.Hered. 78: 361-365, 1987.
Masuda, R., Yoshida, M. C., Sasaki, M., Dempo, K., Mori, M.
High susceptibility to hepatocellular carcinoma development in LEC rats with hereditary hepatitis.
Jpn. J. Cancer Res. 79: 828-835, 1988.
Agui, T., Oka, M., Yamada, T., Sakai, T., Izumi, K., Ishida, Y., Himeno, K., Matsumoto, K.
Maturational arrest from CD4+8+ to CD4+8- thymocytes in a mutant strain (LEC) of rat.
J. Exp. Med. 172: 1615-1624, 1990.
Agui, T., Sakai, T., Matsumoto, K.
Ontogeny of T cell maturation in LEC mutant rats which bear a congenital arrest of maturation from CD4+CD8+ to CD4+CD8- thymocytes.
Eur. J. Immunol. 21: 2537-2541, 1991.
Agui, T., Sakai, T., Himeno, K., Matsumoto, K.
Bone marrow-derived progenitor T cells convey the origin of maturational arrest from CD4+CD8+ to CD4-CD8+ thymocytes in LEC mutant rats.
Eur. J. Immunol. 21: 2277-2280, 1991.
Li, Y., Togashi, Y., Sato, S., Emoto, T., Kang, J. H., Takeichi, N., Kobayashi, H., Kojima, Y., Une, Y., Uchino, J.
Spontaneous hepatic copper accumulation in Long-Evans Cinnamon rats with hereditary hepatitis. A model of Wilson's disease.
J. Clin. Invest. 87: 1858-1861, 1991.
Yamada, T., Natori, T., Izumi, K., Sakai, T., Agui, T., Matsumoto, K.
Inheritance of T helper immunodeficiency (thid) in LEC mutant rats.
Immunogenet. 33: 216-219, 1991.
Hayashi, M., Endoh, D., Kon, Y., Yamashita, T., Hashimoto, N., Sato, F., Kasai, N., Namioka, S.
Higher sensitivity of LEC strain rat in radiation-induced acute intestinal death.
J Vet Med Sci. 54: 269-273, 1992.
Hayashi, M., Endoh, D., Kon, Y., Yamashita, T., Sato, F., Kasai, N., Namioka, S.
Hypersensitivity of LEC strain rats in radiation-induced acute bone- marrow death.
J Vet Med Sci. 55: 13-18, 1993.
Hayashi, M., Okui, T., Endoh, D., Sato, F., Kasai, N., Namioka, S.
Radiation hypersensitivity of LEC strain rats controlled by a single autosomal recessive gene.
Mutat. Res. 314: 135-142, 1994.
Wu, J., Forbes, J. R., Chen, H. S., Cox, D. W.
The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene.
Nature Genet. 7: 541-545, 1994.
Sasaki N, Hayashizaki Y, Muramatsu M, Matsuda Y, Ando Y, Kuramoto T, Serikawa T, Azuma T, Naito A, Agui T, et al.
The gene responsible for LEC hepatitis, located on rat chromosome 16, is the homolog to the human Wilson disease gene.
Biochem Biophys Res Commun. 202(1):512-8, 1994
Wei, K., Muramatsu, Y., Sakai, T., Yamada, T., Matsumoto, K.
Chromosomal mapping of the T-helper immunodeficiency (thid) locus in LEC rats.
Immunogenet. 47: 99-102, 1997.
Agui T, Miyamoto T, Jung CG, Tsumagari T, Masuda K, Manabe T. Related Articles, Links
Genetic linkage analysis of X-ray hypersensitivity in the LEC mutant rat.
Mamm Genome. 11(10):862-5. 2000
Jung CG, Miyamoto T, Tsumagari T, Agui T. Related Articles, Links
Genetic association between low expression phenotype of CD62L (L-selectin) in peripheral CD4+ T cells and the thid (T-helper immunodeficiency) phenotype in the LEC rat.
Exp Anim. 50(4):337-40. 2001
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