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Negrin, CD., McBride, MW., Carswell, HV., Graham, D., Carr, FJ., Clark, JS., Jeffs, B., Anderson, NH., Macrae, IM., Dominiczak, AF.
Reciprocal consomic strains to evaluate y chromosome effects.
Hypertension 37: 391-397, 2001
Kato, N., Tamada, T., Nabika, T., Ueno, K., Gotoda, T., Matsumoto, C., Mashimo, T., Sawamura, M., Ikeda, K., Nara, Y., Yamori, Y.
Identification of quantitative trait loci for serum cholesterol levels in stroke-prone spontaneously hypertensive rats.
Arteriosclerosis, Thrombosis & Vascular Biology. 20: 223-229, 2000
Jeffs, B., Negrin, CD., Graham, D., Clark, JS., Anderson, NH., Gauguier, D., Dominiczak, AF.
Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2.
Hypertension. 35:179-187, 2000
Rubattu S. Giliberti R. Russo R. Gigante B. Ganten U. Volpe M.
Analysis of the genetic basis of the endothelium-dependent impaired vasorelaxation in the stroke-prone spontaneously hypertensive rat: a candidate gene approach.
Journal of Hypertension. 18: 161-165, 2000
Intengan, HD., Schiffrin, EL.
Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats.
Hypertension. 35: 1221-1225, 2000
Kimura, S., Saito, H., Minami, M., Togashi, H., Nakamura, N., Nemoto, M., Parvez HS.
Pathogenesis of vascular dementia in stroke-prone spontaneously hypertensive rats.
Toxicology 153:167-178, 2000
Collison, M., Glazier, AM., Graham, D., Morton, JJ., Dominiczak, MH., Aitman, TJ., Connell, JM., Gould, GW., Dominiczak, AF.
Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.
Diabetes 49: 2222-2226, 2000
Carswell, HV., Anderson, NH., Clark, JS., Graham, D., Jeffs, B., Dominiczak AF., Macrae, IM.
Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat.
Hypertension. 33: 681-685, 1999
Brosnan, MJ., Clark, JS., Jeffs, B., Negrin, CD., van Vooren, P., Arribas, SM., Carswell, H., Aitman, TJ., Szpirer, C., Macrae, IM., Dominiczak, AF.
Genes encoding atrial and brain natriuretic peptides as candidates for sensitivity to brain ischemia in stroke-prone hypertensive rats.
Hypertension. 33: 290-297, 1999
Tagami, M., Yamagata, K., Ikeda, K., Fujino, H., Nara, Y., Nakagawa, K., Kubota, A., Numano, F., Yamori Y.
Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion.
Hypertension Research. 22: 23-29, 1999
Yamori, Y.
Implication of hypertensive rat models for primordial nutritional prevention of cardiovascular diseases.
Clinical & Experimental Pharmacology & Physiology. 26: 568-572, 1999
Ikeda, K., Yamori Y.
Gene related to stroke in stroke-prone spontaneously hypertensive rats.
Clinical & Experimental Pharmacology & Physiology. 26: 566-567, 1999
Mizutani, K., Ikeda, K., Kawai, Y., Yamori, Y.
Biomechanical properties and chemical composition of the aorta in genetic hypertensive rats.
Journal of Hypertension. 17: 481-487, 1999
Hubner, N., Lee, YA., Lindpaintner, K., Ganten, D., Kreutz, R.
Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.
Hypertension. 34: 643-648, 1999
Rubattu, S., Giliberti, R., Ganten ,U., Volpe, M.
Differential brain atrial natriuretic peptide expression co-segregates with occurrence of early stroke in the stroke-prone phenotype of the spontaneously hypertensive rat.
Journal of Hypertension. 17: 1849-1852, 1999
Rubattu, S., Lee-Kirsch, MA., DePaolis, P., Giliberti, R., Gigante, B., Lombardi, A., Volpe, M., Lindpaintner, K.
Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat.
Circ Res 85: 900-905, 1999
Mashimo, T., Nabika, T., Matsumoto, C., Tamada, T., Ueno, K., Sawamura, M., Ikeda, K., Kato, N., Nara, Y., Yamori, Y.
Aging and salt-loading modulate blood pressure QTLs in rats.
Am J Hypertens 12: 1098-1104, 1999
Russo, R., Vecchione, C., Cosentino, F., Natale, A., Mele, AF., Muscolo, M., Savoia, C., Ganten, D., Rubattu, S., Volpe, M.
Impaired vasorelaxant responses to natriuretic peptides in the stroke-prone phenotype of spontaneously hypertensive rats.
Journal of Hypertension. 16: 151-156, 1998
Jeffs, B., Clark, JS., Anderson, NH., Gratton, J., Brosnan,MJ., Gauguier, D., Reid, JL., Macrae, IM., Dominiczak, AF.
Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus.
Nat. Genet. 16: 364-367, 1997
Volpe, M., Iaccarino, G., Vecchione, C., Rizzoni, D., Russo, R., Rubattu, S., Condorelli, G., Ganten, U., Ganten, D., Trimarco, B., Lindpaintner, K.
Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.
Journal of Clinical Investigation. 98: 256-261, 1996
Rubattu, S., Volpe, M., Kreutz, R., Ganten, U., Ganten, D., Lindpaintner, K. Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.
Nature Genetics. 13: 429-434, 1996
Ikeda, K., Nara, Y., Matumoto, C., Mashimo, T., Tamada, T., Sawamura, M., Nabika, T., Yamori, Y.
The region responsible for stroke on chromosome 4 in the stroke-prone spontaneously hypertensive rat.
Biochemical & Biophysical Research Communications. 229: 658-662, 1996
Clark, JS., Jeffs, B., Davidson, AO., Lee, WK., Anderson, NH., Bihoreau, MT., Brosnan, MJ., Devlin, AM., Kelman, AW., Lindpaintner, K., Dominiczak AF.
Quantitative trait loci in genetically hypertensive rats. Possible sex specificity.
Hypertension 28: 898-906, 1996
Volpe, M., Rabattu, S.
Pathophysiological aspects of genetically determined hypertension in rats, with special emphasis on stroke-prone spontaneously hypertensive rats.
Handbook of Hypertension Vol. 16 Experimental and Genetic Models of Hypertension (Ganten D. and de Jong W., eds), pp. 365-394. Elsevier, 1994
Hubner, N., Kreutz, R., Takahashi, S., Ganten, D., Lindpaintner, K.
Unlike human hypertension, blood-pressure in a hereditary hypertensive rat strain shows no linkage to the angiotensinogen locus.
Hypertension 23: 797-801, 1994
Koike, G., Krieger, JE., Jacob, HJ., Mukoyama, M., Pratt, RE., Dzau, VJ.
Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.
Biochemical & Biophysical Research Communications. 198: 380-386, 1994
Hilbert, P., Lindpaintner, K., Beckmann, JS., Serikawa, T., Soubrier, F., Dubay, C., Cartwright, P., De Gouyon, B., Julier, C., Takahasi, S. et al. Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats [see comments].
Nature. 353: 521-529, 1991
Jacob, HJ., Lindpaintner, K., Lincoln, SE., Kusumi, K., Bunker, RK., Mao, YP., Ganten, D., Dzau, VJ., Lander, ES.
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.
Cell 67: 213-224, 1991
Yamori, Y.
Development of the Spontaneously Hypertensive Rat (SHR) and of various spontaneous rat models, and their implications.
Handbook of Hypertension Vol. 4. Experimental and genetic models of hypertension (de Jong W., ed), pp. 224-239. Elsevier, 1984
Tanase, H., Yamori Y., Hansen C. T., Lovenberg, W.
Heart size in inbred strains of rats. Part 1. Genetic determination of the development of cardiovascular enlargement in rats.
Hypertension 4: 864-872, 1982
Yamori, Y., Nagaoka, A., Okamoto, K.
Importane of genetic factors in hypertensive cerebrovascular lesions: An evidence obtained by successive selective breeding of stroke-prone and resistant SHR.
Jpn. Circ. J. 38: 1095-1100, 1974
Okamoto, K., Yamori, Y., Nagaoka, K.
Establishment of the stroke prone spontaneously hypertensive rats (SHR).
Circ. Res. 34/35: 143-153, 1974 |