Strain information  NBRP Rat No: 0212  Strain name: ACI.BUF-Aftm1/Mna  Commmon Name: Rat Genome Database Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan Tel: 0562-93-2486    Fax: 0562-93-4008 Email: mmatsuya@fujita-hu.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  agouti Inbred Generations   Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin This congenic strain was established as a strain with the genetic background of ACI onto which a segment from the BUF/Mna containing the Aftm1 has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010) Strain characteristics This congenic rat develops muscle atrophy in 100% of animals. Breeding Conditions Sib mating. Genotyping References Matsuyama M, Nagayo T Development of thymoma and myasthenia in Buffalo/Mna rats. Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977. Amo H, Saito M, Nagao S, Yagiu S, Takahashi H, Morita H, Morita TM, Matsuyama M. Genetic regulation of slowly progressing mild muscle atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve. 1997 20(10):1258-63. 松山 睦司 , 守口 匡子 , 叶 春霖 , 石川 球美子 , 松浦 晃洋 ACl/NMs-Aftm1/Aftm1系コンジェニックラットにおける筋萎縮(第21回日本胸腺研究会) 日本呼吸器外科学会雑誌 2002 16(4):7a-8a Additional strain information ACI BUF