Strain information  NBRP Rat No: 0473  Strain name: ACI.BUF-Pur1 Ten2/Mna  Commmon Name: ACI/NMna-Pur1-Ten2 Rat Genome Database Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan Tel: 0562-93-2486    Fax: 0562-93-4008 Email: mmatsuya@fujita-hu.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  agouti Inbred Generations  F19 Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. (see references) Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin The proteinuria-susceptible gene, Pur1 (on Chr 13) and the thymus enlargement, Ten2 (on Chr 13) loci of BUF/Mna were transferred to ACI by backcrossing from Matsuyama et al. Congenic rats are established in 2002. Strain characteristics Proteinuria. Breeding Conditions Sib mating. Genotyping References Murayama S, Yagyu S, Higo K, Ye C, Mizuno T, Oyabu A, Ito M, Morita H, Maeda K, Serikawa T, Matsuyama M. A genetic locus susceptible to the overt proteinuria in BUF/Mna rat. Mamm Genome. 9(11):886-8, 1998. Additional strain information