Strain information
NBRP Rat No: 0486
Strain name
: ACI.F344-(
D16Nkg74
)/Nkg
Commmon Name:
Rat Genome Database
Principal Investigator:
Hitoshi Nakagama National Cancer center 5-1-1 Tsukiji, Chuo-ku 104-0045 Tokyo Japan
Tel: 03-3542-2511 Fax: 03-3542-2530
Email: hnakagam@ncc.go.jp
Preservation Status:
Embryo
Sperm
Living Animals
Coat Color
agouti
Inbred Generations
F3 (Oct 2007)
Usage Restrictions
In publishing, an acknowledgment to the DEPOSITOR is requested.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Origin
F344 rats are susceptible and ACI rats are resistant to PhIP(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)-induced ACF (aberrant crypt foci) formation (Nagao, 1998). Targeting on susceptible gene for colon tumor on rat chromosome 16 (Nakagama, 1999), this congenic strain was established. A sub congenic strain of ACI/N.F344-(
D16Rat12-D16Mco2
)/Nkg (NBRP No.0401) (Jul 7, 2009)
Strain characteristics
This congenic strain has almost the same characterization as shown in ACI/N. (Jul 7, 2009)
Breeding Conditions
Good breeding performance.
Genotyping
References
Additional strain information