Strain information
 NBRP Rat No: 0505  Strain name: ACI.BUF-(D7Wox16-D7Rat69)/Mna  Commmon Name: ACI/N-Tsr1/Tsr1 Rat Genome Database
Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan
Tel: 0562-93-2486    Fax: 0562-93-4008 Email: mmatsuya@fujita-hu.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  agouti
Inbred Generations  N?F8
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin The thymoma susceptible locus of rat-1, Tsr1 (on Chr 7) was transferred from BUF/Mna to ACI/NMs by repeated backcrossing. (Matsuyama, 2008)
Strain characteristics About 75% F1 rats which generated by crossing ACI.BUF-(D7Wox16-D7Rat69)/Mna rats with ACI/NMs rats develop tymoma at 2 years of age.
Breeding Conditions Sib mating.
Genotyping
References Matsuyama M, Kato K, Higo-Moriguchi K, Yamada T, Kuramoto T, Kuroda M.
Establishment of thymoma-prone congenic rat strain, ACI.BUF/Mna-Tsr1/Tsr1.
J Cancer Res Clin Oncol. 2008 134(7):789-92.
Additional strain information