Japanese
 NBRP Rat No: 0027 Strain NameKND/Tky Commmon Name: KND, Komeda non-diabetic rat
 Principal Investigator  Eiichi Kawamoto
 Organization   Tokyo Medical University Institution: Animal Research Center
 Address  6-1-1 Shinjuku, Shinjuku-ku,

160-8402 Tokyo

 JAPAN
 Telephone  03-3351-6141  Fax:  03-3350-8689  kawamoto@tokyo-med.ac.jp
 Inbred Generations   F23+39 
   
 Coat Color
 Deposition Status
 
 black hooded (a,B,C,h)
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability  Japan SLC,Inc. 
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin Komeda diabetes-prone rat developed by Komeda from Long-Evans Tokushima Lean (LETL) rat at Tokyo Medical College in 1996. Komeda non Diabetic Rats were established simultaneusely as controls. 
 Strain Characteristics Control strain for KDP rat (NBRP No.0026). 
 Breeding Conditions Sib mating. 
 Genotyping  
 References  Yokoi N, Komeda K, Wang HY, Yano H, Kitada K, Saitoh Y, Seino Y, Yasuda K, Serikawa T, Seino S.
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
Nat Genet. 31(4):391-4, 2002

Komeda K, Noda M, Terao K, Kuzuya N, Kanazawa M, Kanazawa Y.
Establishment of two substrains, diabetes-prone and non-diabetic, from Long-Evans Tokushima Lean (LETL) rats.
Endocr J. 45(6):737-44, 1998