NBRP Rat No: 0144 Strain NameSHRSP/Ngsk Commmon Name: SHRSP長崎
 Principal Investigator  Masami Niwa
 Organization   School of Allied Medical Sciences, Nagasaki University Department of Pharmacology
 Address  12-4, Sakamoto, Nagasaki

852-8523 Nagasaki

 Telephone  095-849-7043  Fax:  095-849-7044  niwa@net.nagasaki-u.ac.jp
 Inbred Generations   F?+26 (April 2012) 
 Coat Color
 Deposition Status
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others Orthopaedic Surgery
  Control Strains   Reporter gene Strains  
 Origin The SHRSP/Ngsk is originated in the SHRSP given from Prof. Okamoto at Kinki University, Japan in 1980. 
 Strain Characteristics SHRSP/Ngsk is little smaller than SHR/Izm in size. Age of occurrence of stroke is stable, and circulation dynamics and pathological changes are similar to those of SHRSP/Izm. The frequncy of necrosis at the epiphysis is little higher than SHRSP/Izm. 
 Breeding Conditions Keep with normal SHRSP diet. Sib mating. 
 References  Sakurai-Yamashita Y, Nabika T, Niwa M.
Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats.
Cell Mol Neurobiol. 2010 Mar;30(2):283-7.

Yamashita K, Niwa M, Kataoka Y, Shigematsu K, Himeno A, Tsutsumi K, Nakano-Nakashima M, Sakurai-Yamashita Y, Shibata S, Taniyama K.
Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia.
J Neurochem. 1994 Sep;63(3):1042-51.