Strains

Japanese

NBRP Rat No: 0144

Strain Name: SHRSP/Ngsk

Commmon Name: SHRSP長崎

Principal Investigator

Masami Niwa

Organization

School of Allied Medical Sciences, Nagasaki University Department of Pharmacology

Address

12-4, Sakamoto, Nagasaki

852-8523 Nagasaki

Japan

Telephone

095-849-7043

Fax: 095-849-7044

niwa@net.nagasaki-u.ac.jp

Inbred Generations

F?+26 (April 2012)

Coat Color

Deposition Status

albino (c)

Embryo Sperm Live Animals

Usage Restrictions

Genetic Status

Inbred

Segregating

Congenic

Consomic

Recombinant

Coisogenic

Spont. Mutant

Transgene

Ind. Mutant

Others

Comercial Availability

Research Category

Diabetes Obesity

Neurobiology

Ophthalmology

Dentistry

Cardio- Hypertension

Oncology

Metabolism

Otorhinology

Immunology

Infectious Disease

Osteology

Internal Medicine

Dermatology

Reproduction

Development

Behavior

Hematology

Urology

Pharmacology

Others Orthopaedic Surgery

Control Strains

Reporter gene Strains

Gene

Origin

The SHRSP/Ngsk is originated in the SHRSP given from Prof. Okamoto at Kinki University, Japan in 1980.

Strain Characteristics

SHRSP/Ngsk is little smaller than SHR/Izm in size. Age of occurrence of stroke is stable, and circulation dynamics and pathological changes are similar to those of SHRSP/Izm. The frequncy of necrosis at the epiphysis is little higher than SHRSP/Izm.

Breeding Conditions

Keep with normal SHRSP diet. Sib mating.

Genotyping

References

Sakurai-Yamashita Y, Nabika T, Niwa M.
Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats.
Cell Mol Neurobiol. 2010 Mar;30(2):283-7.

Yamashita K, Niwa M, Kataoka Y, Shigematsu K, Himeno A, Tsutsumi K, Nakano-Nakashima M, Sakurai-Yamashita Y, Shibata S, Taniyama K.
Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia.
J Neurochem. 1994 Sep;63(3):1042-51.