Japanese
NBRP Rat No: 0151
Strain Name
:
SDR/Slc
Commmon Name: Spontaneous Dwarf Rat
Principal Investigator
Representative Director
Organization
Japan SLC, Inc
Address
3371-8, Kotoh-cho, Hamamatsu
431-1103 Shizuoka
Japan
Telephone
053-486-3178
Fax: 053-486-3156
slc01@jslc.co.jp
Inbred Generations
F?+10
Coat Color
Deposition Status
albino (c)
Embryo
Sperm
Live Animals
Usage Restrictions
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
Gh1: growth hormone 1
Origin
In 1977, small mutant rats were discovered in a colony of Sprague Dawley rats at Morishita Pharmaceutical Co., transferred to Japan SLC, Inc.
Strain Characteristics
Postnatal growth retardation. Pituitary dwarfism. Growth hormone (<i>Gh1</i>) deficiency caused by a nonsense point mutation in the Gh1 gene.
Breeding Conditions
Sib mating. Poor breeding performance.
Genotyping
References