Japanese
 NBRP Rat No: 0151 Strain NameSDR/Slc Commmon Name: Spontaneous Dwarf Rat
 Principal Investigator  Representative Director
 Organization   Japan SLC, Inc 
 Address  3371-8, Kotoh-cho, Hamamatsu

431-1103 Shizuoka

 Japan
 Telephone  053-486-3178  Fax:  053-486-3156  slc01@jslc.co.jp
 Inbred Generations   F?+10 
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene Gh1: growth hormone 1
 Origin In 1977, small mutant rats were discovered in a colony of Sprague Dawley rats at Morishita Pharmaceutical Co., transferred to Japan SLC, Inc. 
 Strain Characteristics Postnatal growth retardation. Pituitary dwarfism. Growth hormone (<i>Gh1</i>) deficiency caused by a nonsense point mutation in the Gh1 gene. 
 Breeding Conditions Sib mating. Poor breeding performance. 
 Genotyping  
 References