Japanese
 NBRP Rat No: 0152 Strain Name: HWY/Slc Commmon Name: Hairless Wistar Yagi
 Principal Investigator  Representative Director
 Organization   Japan SLC, Inc 
 Address  3371-8, Kotoh-cho, Hamamatsu

431-1103 Shizuoka

  Japan
 Telephone  053-486-3178  Fax:  053-486-3156  slc01@jslc.co.jp
 Inbred Generations   F?+11 
   
 Coat Color
 Deposition Status
 
 albino, hairless
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability  Japan SLC, Inc 
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin A hairless mutant rat was found in a colony of Wistar rats (Crj: Wistar), transferred to Japan SLC, Inc from Yagi Memorial Park, 1993. 
 Strain Characteristics Short pelage is sparsely distributed at weaning but, with growth, they exhibit almost complete hairlessness. Follicular cysts are seen in the dermis in 9 weeks of age. These phenotypes are due to autosomal dominant inheritance. 
 Breeding Conditions  
 Genotyping  
 References  Kim H, Yoshihara M, Suyama M.
Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms.
Mamm Genome. 2020 Apr;31(3-4):86-94.

Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157

Ishii Y, Tsutsui S, Doi K, Itagaki S.
Hair follicles of young Wistar strain hairless rats: a histological study.
J Anat. 1997 Jul;191 ( Pt 1):99-106.