Japanese
NBRP Rat No: 0180
Strain Name
:
F344.Cg-
Lepr
fa
(
D14Rat23-D14Rat12
)/Tj
Commmon Name: F.ZF/O-<i>lepr,Nidd2/of</i>
Principal Investigator
Kozo Matsumoto
Organization
The University of Tokushima Graduate School of Medicine Institute of Health Biosciences, Division of Animal Research Resources
Address
3-18-15 Kuramoto-cho
770-8503 Tokushima
JAPAN
Telephone
088-633-9278
Fax: 088-600-9429
kozo@anex.med.tokushima-u.ac.jp
Inbred Generations
N(5)F5
Coat Color
Deposition Status
Embryo
Sperm
Live Animals
Usage Restrictions
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
Origin
Established as speed congenics (5 generations, microsatellite marker) at the University of Tokushima School of Medicine, Institute for Animal Experimentation in 2002. Afterwards, maintained by sib mating.
Strain Characteristics
Obesity. Show hyperglycemia in the OGTT assay.
Breeding Conditions
Good breeding performance.
Genotyping
References
Kose H, Yamada T, Matsumoto K.
Single Diabetic QTL Derived from OLETF Rat Is a Sufficient Agent for Severe Diabetic Phenotype in Combination with Leptin-Signaling Deficiency.
Exp Diabetes Res. 2012;2012:858121.Epub 2012 Dec 5.