NBRP Rat No: 0195 Strain NameWKY/Izm Commmon Name: 
 Principal Investigator  Yukio Yamori
 Organization   Disease Model Cooperative Research Association 
 Address  Kenju Bldg. 2F86, Jodoji-Shimobanba-cho, Sakyo-ku

606-8413 Kyoto

 Telephone  075-761-2371  Fax:  075-761-2371  dmcra@j.email.ne.jp
 Inbred Generations   F110+? 
 Coat Color
 Deposition Status
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association.
They must also comply with the decisions made by the board of directors. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Strain Characteristics normotension. control strain for SHR/Izm (NBRP No.0194) and SHRSP/Izm (NBRP No.0195) 
 Breeding Conditions Good breeding performance. 
 References  Yamagata K, Yamamoto M, Kawakami K, Ohara H, Nabika T.
Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
Neuroscience. 267:277-285, 2014.

Yamori,Y et.al. : The Spontaneously Hypertensive Rat. In: Textbook of hypertension,
ed. By Swales,J.D.,Blackwell Scientific Publication, Oxford, 1994,pp447-455