Japanese
 NBRP Rat No: 0201 Strain NameBUF.Cg-Foxn1rnu/Mna Commmon Name: BUF/Mna-<i>Foxn1<sup>rnu</sup></i>
 Principal Investigator  Mutsushi Matsuyama
 Organization   Fujita Health University  Department of Virology and Parasitology
 Address  1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi

420-1192 Aichi

 Japan
 Telephone  0562-93-2486  Fax:  0562-93-4008  mmatsuya@fujita-hu.ac.jp
 Inbred Generations    
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene Foxn1: forkhead box N1
 Origin BUF/Mna, NN1H-Rnu/Rnu 
 Strain Characteristics spontaneous development of epithelial thymoma, nephrotic syndrome 
 Breeding Conditions BUF/Mna-Rnu/+ × BUF/Mna-Rnu/Rnu.
Sib mating. 
 Genotyping <a href="http://www.anim.med.kyoto-u.ac.jp/nbr/documents/PCR_Gene/Foxn1_rnu_en.pdf">Genotyping protocol for Foxn1</a> 
 References  Matsuyama M, Yamada C, Kojima A.
Possible single dosage effects of the nude gene: suppression of spontaneous development of thymoma and nephropathy in BUF/Mna-rnu/+ rats.
Jpn J Cancer Res. 78(1):40-4, 1987.

Matsuyama, M., et al.: in "Immune-Deficient Animals in Experimental Medicine, eds. B. Wu, J. Zheng, Karger, New York, 1989