Strain information

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NBRP Rat No: 0205

Strain name: WKY.BUF-Pur1w/Mna

Commmon Name:

Rat Genome Database

Principal Investigator:

Mutsushi MatsuyamaFujita Health University

Preservation Status:

Embryo Sperm Living Animals

Coat Color

albino (c)

Inbred Generations

Usage Restrictions

In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

Origin

This congenic strain was established as a strain with the genetic background of WKY onto which a segment from the BUF/Mna containing the proteinuria-susceptible gene, Pur1 (on chr.13, Murayama, 1998) has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010)

Strain characteristics

Mild nephrosis.

Breeding Conditions

Sib mating.

Genotyping

References

Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Kato F, Watanabe M, Matsuyama M.
Nephrotic syndrome in spontaneous thymoma rats, Buffalo/Mna.
Biomed Res 1983 4:105-9.

Murayama S, Yagyu S, Higo K, Ye C, Mizuno T, Oyabu A, Ito M, Morita H, Maeda K, Serikawa T, Matsuyama M.
A genetic locus susceptible to the overt proteinuria in BUF/Mna rat.
Mamm Genome. 1998 Nov;9(11):886-8.

Additional strain information (Japanese only)

BUF