Japanese
 NBRP Rat No: 0212 Strain Name: ACI.BUF-Aftm1/Mna Commmon Name: 
 Principal Investigator  Mutsushi Matsuyama
 Organization   Fujita Health University  Department of Virology and Parasitology
 Address  1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi

420-1192 Aichi

  Japan
 Telephone  0562-93-2486  Fax:  0562-93-4008  mmatsuya@fujita-hu.ac.jp
 Inbred Generations    
   
 Coat Color
 Deposition Status
 
 agouti
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin This congenic strain was established as a strain with the genetic background of ACI onto which a segment from the BUF/Mna containing the <i>Aftm1</i> has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010) 
 Strain Characteristics This congenic rat develops muscle atrophy in 100% of animals.  
 Breeding Conditions Sib mating. 
 Genotyping  
 References  Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Amo H, Saito M, Nagao S, Yagiu S, Takahashi H, Morita H, Morita TM, Matsuyama M.
Genetic regulation of slowly progressing mild muscle atrophy in fast-twitch muscles of BUF/Mna rats.
Muscle Nerve. 1997 20(10):1258-63.

松山 睦司 , 守口 匡子 , 叶 春霖 , 石川 球美子 , 松浦 晃洋
ACl/NMs-Aftm1/Aftm1系コンジェニックラットにおける筋萎縮(第21回日本胸腺研究会)
日本呼吸器外科学会雑誌 2002 16(4):7a-8a