Strain information

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NBRP Rat No: 0279

Strain name: DA-Tg(CAG-lacZ)19Jmsk

Commmon Name: LacZ19

Rat Genome Database

Principal Investigator:

Eiji KobayashiCenter for Molecular Medicine, Jichi Medical School

Preservation Status:

Embryo Sperm Living Animals

Coat Color

Inbred Generations

Usage Restrictions

The recipient is requested to cite in the following literature designated by the DEPOSITOR.

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

lacZ: beta-galactosidase, E. coli

Origin

This strain was established at Jichi Medical School.

Strain characteristics

This transgenic strain expresses LacZ gene ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscle. The strain NBRP No.0280 (line30) is more strongly stained by X-gal staining.

Breeding Conditions

Good breeding performance.

Genotyping

Genotyping protocol for LacZ

References

Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E.
Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardium.
Biochem Biophys Res Commun. 2003 Jun 13;305(4):904-8.

Additional strain information (Japanese only)