NBRP Rat No: 0448 Strain NameSHR/2Dmcr Commmon Name: SHR2/Dmcr, SHRB2/Izm
 Principal Investigator  Yukio Yamori
 Organization   Disease Model Cooperative Research Association 
 Address  Kenju Bldg. 2F86, Jodoji-Shimobanba-cho, Sakyo-ku

606-8413 Kyoto

 Telephone  075-761-2371  Fax:  075-761-2371  dmcra@j.email.ne.jp
 Inbred Generations   F119 
 Coat Color
 Deposition Status
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association. They must also comply with the decisions made by the board of directors.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Strain Characteristics hypertension, cardiac hypertrophy and nephrosclerosis 
 Breeding Conditions Sib mating. 
 References  Gotoda T, Iizuka Y, Kato N, Osuga J, Bihoreau MT, Murakami T, Yamori Y, Shimano H, Ishibashi S, Yamada N.
Absence of Cd36 mutation in the original spontaneously hypertensive rats with insulin resistance.
Nat Genet. 1999 Jul;22(3):226-8.