Japanese
 NBRP Rat No: 0307 Strain Name: DOB/Oda Commmon Name: DOB
 Principal Investigator  Senichi Oda
 Organization   Nagoya University  Graduate School of Bio-Agricultural Sciences
 Address  Furo-cho, Chigusa-ku, Nagoya City

464-8601 Aichi

  Japan
 Telephone  052-789-4179  Fax:  052-789-4179  oda@agr.nagoya-u.ac.jp
 Inbred Generations   F14+1+14 (April 2012) 
   
 Coat Color
 Deposition Status
 
 
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin DOB is a partial inbred strain which originated from wild rats captured at the Shitara field, Graduate School of Bioagricultural Sciences and School of Agricultural Sciences Nagoya University. Inbred Line was established in 2009. (Jun 18, 2010) 
 Strain Characteristics A Japanese wild-derived rat strain. Comparing of the genetic profile of the DOB rats (F12) with those of the laboratory inbred strains using 357 SSLP markers showed quite high polymorphic rates, which varied more than 90%. DOB rat has potential to be the reference strain in genetic linkage analysis. (Jun 18, 2010) 
 Breeding Conditions Sib mating. 
 Genotyping  
 References  Kim H, Yoshihara M, Suyama M.
Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms.
Mamm Genome. 2020 Apr;31(3-4):86-94.

Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157

Kuramoto T, Inoue S, Neoda Y, Yamasaki K, Hashimoto R, Mashimo T, Oda S, Serikawa T.
Genetic and phenotypic characterization of a Japanese wild-derived DOB/Oda rat strain.
Mamm Genome. 2013 Aug;24(7-8):303-8. Epub 2013 Jul 30.

Watanabe K, Wada K, Ohashi T, Okubo S, Takekuma K, Hashizume R, Hayashi J, Serikawa T, Kuramoto T, Kikkawa Y.
A 5-bp Insertion in Mip Causes Recessive Congenital Cataract in KFRS4/Kyo Rats.
PLoS One, 2012, 7 (11), e50737.

岡島涼子、庫本高志、真下知士、鶴見東志子、Zhang Zouming、目加田和之、夏目明香、町田侑平、織田銑一、芹川忠夫
日本産野生由来DOBラットの遺伝的特徴
第55回日本実験動物学会総会 2008.5.15-17

井上聡子、城ヶ原貴通、森部絢嗣、織田銑一
日本産野生由来ラット近交系DOBの形態学的特徴
第56回日本実験動物学会総会 2009.5.15-16

井上聡子、庫本高志、根小田祐基、山崎賢一、岡島涼子、真下知士、織田銑一、芹川忠夫
日本で捕獲された野生ラットに由来する近交系DOB/Odaの特性解析
第57回日本実験動物学会総会 2010.5.12-14