Strains

Japanese

NBRP Rat No: 0307

Strain Name: DOB/Oda

Commmon Name: DOB

Principal Investigator

Senichi Oda

Organization

Nagoya University Graduate School of Bio-Agricultural Sciences

Address

Furo-cho, Chigusa-ku, Nagoya City

464-8601 Aichi

Japan

Telephone

052-789-4179

Fax: 052-789-4179

oda@agr.nagoya-u.ac.jp

Inbred Generations

F14+1+14 (April 2012)

Coat Color

Deposition Status

Embryo Sperm Live Animals

Usage Restrictions

In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.

Genetic Status

Inbred

Segregating

Congenic

Consomic

Recombinant

Coisogenic

Spont. Mutant

Transgene

Ind. Mutant

Others

Comercial Availability

Research Category

Diabetes Obesity

Neurobiology

Ophthalmology

Dentistry

Cardio- Hypertension

Oncology

Metabolism

Otorhinology

Immunology

Infectious Disease

Osteology

Internal Medicine

Dermatology

Reproduction

Development

Behavior

Hematology

Urology

Pharmacology

Others

Control Strains

Reporter gene Strains

Gene

Origin

DOB is a partial inbred strain which originated from wild rats captured at the Shitara field, Graduate School of Bioagricultural Sciences and School of Agricultural Sciences Nagoya University. Inbred Line was established in 2009. (Jun 18, 2010)

Strain Characteristics

A Japanese wild-derived rat strain. Comparing of the genetic profile of the DOB rats (F12) with those of the laboratory inbred strains using 357 SSLP markers showed quite high polymorphic rates, which varied more than 90%. DOB rat has potential to be the reference strain in genetic linkage analysis. (Jun 18, 2010)

Breeding Conditions

Sib mating.

Genotyping

References

Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157

Kuramoto T, Inoue S, Neoda Y, Yamasaki K, Hashimoto R, Mashimo T, Oda S, Serikawa T.
Genetic and phenotypic characterization of a Japanese wild-derived DOB/Oda rat strain.
Mamm Genome. 2013 Aug;24(7-8):303-8. Epub 2013 Jul 30.

Watanabe K, Wada K, Ohashi T, Okubo S, Takekuma K, Hashizume R, Hayashi J, Serikawa T, Kuramoto T, Kikkawa Y.
A 5-bp Insertion in Mip Causes Recessive Congenital Cataract in KFRS4/Kyo Rats.
PLoS One, 2012, 7 (11), e50737.

岡島涼子、庫本高志、真下知士、鶴見東志子、Zhang Zouming、目加田和之、夏目明香、町田侑平、織田銑一、芹川忠夫
日本産野生由来DOBラットの遺伝的特徴
第55回日本実験動物学会総会 2008.5.15-17

井上聡子、城ヶ原貴通、森部絢嗣、織田銑一
日本産野生由来ラット近交系DOBの形態学的特徴
第56回日本実験動物学会総会 2009.5.15-16

井上聡子、庫本高志、根小田祐基、山崎賢一、岡島涼子、真下知士、織田銑一、芹川忠夫
日本で捕獲された野生ラットに由来する近交系DOB/Odaの特性解析
第57回日本実験動物学会総会 2010.5.12-14