| Strain Characteristics |
Spontaneous tumours 46% testes, 16% adrenal, 5% pituitary, 6% skin and ear duct and fewer of other types in males; 21% pituitary, 13% uterus, 11% mammary gland, 6% adrenal and fewer of other types in females. Other conditions include 28% of males and 20% of females with absent, hypoplastic or cystic kidneys on one side sometimes associated with an absent or defective uterine horn or atrophic testes on the same side (Maekawa and Odashima 1975). These abnormalities have a polygenic mode of inheritance (Cramer and Gill 1975). |
| References |
Ueta H, Kitazawa Y, Sawanobori Y, Ueno T, Ueha S, Matsushima K, Matsuno K.
Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.
Int Immunol. 2018 Jan 18. [Epub ahead of print]
Kuramoto T, Nakanishi S, Ochiai M, Nakagama H, Voigt B, Serikawa T.<br />
Origins of Albino and Hooded Rats: Implications from Molecular Genetic Analysis across Modern Laboratory Rat Strains.<br />
PLoS One. 2012;7(8):e43059.<br />
Kuramoto T, Yokoe M, Hashimoto R, Hiai H, Serikawa T.<br />
A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene.<br />
BMC Genetics 12:91, 2011<br />
<br />
Matsuno K, Ueta H, Shu Z, Xue-Dong X, Sawanobori Y, Kitazawa Y, Bin Y, Yamashita M, Shi C.<br />
The microstructure of secondary lymphoid organs that support immune cell trafficking.<br />
Arch Histol Cytol. 2010;73(1):1-21. Review.<br /><br />
LinksShull JD, Lachel CM, Strecker TE, Spady TJ, Tochacek M, Pennington KL, Murrin CR, Meza JL, Schaffer BS, Flood LA, Gould KA.<br />
Genetic bases of renal agenesis in the ACI rat: mapping of Renag1 to chromosome 14.<br />
Mamm Genome. 17(7):751-9, 2006. |