Japanese
NBRP Rat No: 0377
Strain Name
:
F344-Tg(CCR5)1Hik
Commmon Name: F344/DuCrlCrlj-Tg(CCR5)1Hik, F344-hCCR5
Principal Investigator
Hisatoshi Shida
Organization
Hokkaido University Molecular virology, Institute for genetic medicine
Address
Kita 15 Nishi 7, Kita-ku, Sapporo
060-0815 Hokkaido
Japan
Telephone
011-706-7543
Fax: 011-706-7543
hmyy2010@yahoo.co.jp
Inbred Generations
5
Coat Color
Deposition Status
albino (c)
Embryo
Sperm
Live Animals
Usage Restrictions
Use of BIOLOGICAL RESOURCE shall be limited to a collaborative research with the DEPOSITOR. This condition is not limited to two-year period of the deposition.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
CCR5: C-C motif chemokine receptor 5
Origin
A BAC carrying the genomic region of the human CCR5 was introduced to F344/DuCrj. (Nov 5, 2009)
Strain Characteristics
human CCR5 is expressed in CD4+ T cells and macrophages.
Breeding Conditions
normal breeding.
Genotyping
Primer(GCTCAGGTCCCTACTGG, GGGCTGCGATTTGCTTC), PCR condition(annealing:50C, extension:20sec, 40 cycles), product size: ~140 bp
References