Japanese
 NBRP Rat No: 0377 Strain NameF344-Tg(CCR5)1Hik Commmon Name: F344/DuCrlCrlj-Tg(CCR5)1Hik, F344-hCCR5
 Principal Investigator  Hisatoshi Shida
 Organization   Hokkaido University Molecular virology, Institute for genetic medicine
 Address  Kita 15 Nishi 7, Kita-ku, Sapporo

060-0815 Hokkaido

 Japan
 Telephone  011-706-7543  Fax:  011-706-7543  hmyy2010@yahoo.co.jp
 Inbred Generations   5 
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions  Use of BIOLOGICAL RESOURCE shall be limited to a collaborative research with the DEPOSITOR. This condition is not limited to two-year period of the deposition. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene CCR5: C-C motif chemokine receptor 5
 Origin A BAC carrying the genomic region of the human CCR5 was introduced to F344/DuCrj. (Nov 5, 2009) 
 Strain Characteristics human CCR5 is expressed in CD4+ T cells and macrophages. 
 Breeding Conditions normal breeding. 
 Genotyping Primer(GCTCAGGTCCCTACTGG, GGGCTGCGATTTGCTTC), PCR condition(annealing:50C, extension:20sec, 40 cycles), product size: ~140 bp  
 References