Japanese
 NBRP Rat No: 0403 Strain Name: DA-Tg(Alb-TTR*V30M)9Jmsk Commmon Name: DA-<i>Tg(Alb-ATTR)9Jmsk</i>, ATTR9
 Principal Investigator  Eiji Kobayashi
 Organization   Center for Molecular Medicine, Jichi Medical School Division of Organ Replacement Research
 Address  3311-1, Yakushiji, Shimono-shi, Tochigi

329-0498 Tochigi

  Japan
 Telephone  0285-58-7446  Fax:  0285-44-5365  eijikoba@jichi.ac.jp
 Inbred Generations    
   
 Coat Color
 Deposition Status
 
 
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing, the references designated by the DEPOSITOR is requested to be cited, and an acknowledgment to the DEPOSITOR is requested. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene transthyretin: TTR (human Amyloidogenic transthyretin (ATTR) V30M)
 Origin This strain was established at Jichi Medical School. 
 Strain Characteristics This is the strain expresses human Amyloidogenic transthyretin (ATTR) V30M driven by the mouse albumin enhancer/promoter, may be a useful animal model for the liver transplantation studies. 
 Breeding Conditions  
 Genotyping  
 References  Ueda M, Ando Y, Hakamata Y, Nakamura M, Yamashita T, Obayashi K, Himeno S, Inoue S, Sato Y, Kaneko T, Takamune N, Misumi S, Shoji S, Uchino M, Kobayashi E.
A transgenic rat with the human ATTR V30M: a novel tool for analyses of ATTR metabolisms.
Biochem Biophys Res Commun. 2007 12;352(2):299-304.