Japanese
 NBRP Rat No: 0044 Strain Name: NIG-III/Hok Commmon Name: NIG-III
 Principal Investigator  Kazuhiro Kitada
 Organization   Creative Research Initiative "Sousei", Hokkaido University Laboratory of Mammalian Genetics
 Address  Kita 10 Nishi 8, Kita-ku

060-0810 Hokkaido

  JAPAN
 Telephone  011-706-3582  Fax:  011-726-3476  kkitada@cast.hokudai.ac.jp
 Inbred Generations   F33+84+23 (April 2012) 
   
 Coat Color
 Deposition Status
 
 yellow agouti (a,B,C,H,pm)
  Embryo      Sperm      Live Animals
 Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
For a commercial use of this resource, a new contract must be concluded between the depositor and the recipient. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin National Institute of Genetics(Ms)→Hokkaido University, Cancer 1975 F32→Hokkaido University, Laboratory of Experimental Animal Science(Hok) 1975, F33→Hokkaido University, Center for Experimental Plants & Animals(Hok) 1982, F53 
 Strain Characteristics From a mating in 1956 between a wild rat trapped in Misima, Japan, and Castle's black rat. pink-eyed dilution (p) mutation. 
 Breeding Conditions Good breeding performance. Sib-mating. 
 Genotyping  
 References  Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157

Igarashi M, Hippo Y, Ochiai M, Fukuda H, Nakagama H.
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Biochem Biophys Res Commun. 2013 Dec 13. pii: S0006-291X(13)02128-1.

Kuramoto T, Gohma H, Kimura K, Wedekind D, Hedrich HJ, Serikawa T.
The rat pink-eyed dilution (p) mutation: an identical intragenic deletion in pink-eye dilute-coat strains and several Wistar-derived albino strains.
Mamm Genome. 16(9):712-9, 2005.