Japanese
 NBRP Rat No: 0454 Strain NameSHRSP/5Dmcr Commmon Name: SHRSP5/Dmcr, SHRALR/Izm, ALR (arteriolipidosis-prone rats), SHRAP (arteriolipidosis-prone SHR)
 Principal Investigator  Yukio Yamori
 Organization   Disease Model Cooperative Research Association 
 Address  Seisan Kaihatsukagakukenkyujyo 3F-Simogamo Morimotocho15-Sakyoku

606-0805 Kyoto

 Japan
 Telephone  075-744-0071  Fax:  075-744-0071  dmcra@j.email.ne.jp
 Inbred Generations   F31 
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association. They must also comply with the decisions made by the board of directors.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin  
 Strain Characteristics Hypertension, cardiomegaly, nephrosclerosis 
 Breeding Conditions  
 Genotyping  
 References  Moriya T, Kitamori K, Naito H, Yanagiba Y, Ito Y, Yamagishi N, Tamada H, Jia X, Tsuchikura S, Ikeda K, Yamori Y, Nakajima T.
Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat.
Environ Health Prev Med. 2012 Nov;17(6):444-56.

Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K, Tsuchikura S, Yasui N, Ikeda K, Moriya T, Yamori Y, Nakajima T.
Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr.
Environ Health Prev Med. 2012 May;17(3):173-82.