Japanese
 NBRP Rat No: 0486 Strain Name: ACI.F344-(D16Nkg74)/Nkg Commmon Name: 
 Principal Investigator  Hitoshi Nakagama
 Organization   National Cancer center  Biochemistry Division
 Address  5-1-1 Tsukiji, Chuo-ku

104-0045 Tokyo

  Japan
 Telephone  03-3542-2511  Fax:  03-3542-2530  hnakagam@ncc.go.jp
 Inbred Generations   F3 (Oct 2007) 
   
 Coat Color
 Deposition Status
 
 agouti
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing, an acknowledgment to the DEPOSITOR is requested.  
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin F344 rats are susceptible and ACI rats are resistant to PhIP(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)-induced ACF　(aberrant crypt foci) formation (Nagao, 1998). Targeting on susceptible gene for colon tumor on rat chromosome 16 (Nakagama, 1999), this congenic strain was established. A sub congenic strain of ACI/N.F344-(<i>D16Rat12-D16Mco2</i>)/Nkg (NBRP No.0401) (Jul 7, 2009) 
 Strain Characteristics This congenic strain has almost the same characterization as shown in ACI/N. (Jul 7, 2009) 
 Breeding Conditions Good breeding performance. 
 Genotyping  
 References