The National BioResource Project for the Rat in Japan

Strain information

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NBRP Rat No: 0485
Strain name: SR/JrNgs
Commmon Name: Dhal SR Rat
Principal Investigator:
Kazutaka OhsawaCenter for Frontier Life Sciences, Nagasaki University
Preservation Status:
Coat Color
albino (c)
Inbred Generations
F?+71 (May 2009)
Usage Restrictions
Genetic Status
Comercial Availability
Research Category
Gene Affected
Origin
DahlSR/JrNgs rat derived from Dr. Rapp JP of Department of Physiology, Medical University of Ohio to Nagasaki Univ. in 1986.
Strain characteristics
Resistance to the hypertensive effect of a high salt (NaCl) diet. Control strain for SS/JrNgs (NBRP No.0484).
Breeding Conditions
Sib mating.
Genotyping
References
Baba K, Mulrow PJ, Franco-Saenz R, and Rapp JP.
Suppression of Adrenal Renin in Dahl Salt-Sensitive Rats.
Hypertension 8:1149-1153, 1986.

Kusano E, Baba K, Rapp JP, Franco-Saenz R, and Mulrow PJ.
Adrenal Renin in Dahl Salt-Sensitive Rats: A Genetic Study.
J Hypertension 4 (suppl 5):S20-S22, 1986.

Kawai K, Baba K, Senba M, Nakamura T, Doi Y, yamaguchi T, Hashiba K and Tsuchiyama H
Effect of the adrenal inhibitor trilostane on the morphology of the adrenocortical cells of Dahl salt-sensitive and Dahl salt-resistant rats.
Int J Exp Path 72:456-462, 1991.

Ferdaus MZ, Xiao B, Ohara H, Nemoto K, Harada Y, Saar K, Hübner N, Isomura M, Nabika T.
Identification of stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
PLoS One. 9(4):e95091, 2014.
Additional strain information (Japanese only)