Japanese
NBRP Rat No: 0495
Strain Name
:
KFRS4A/Kyo
Commmon Name: SRR04-A
Principal Investigator
Takashi Kuramoto
Organization
Graduate School of Medicine, Kyoto University Institute of Laboratory Animals
Address
Yoshidakonoe-cho, Sakyo-ku
606-8501 Kyoto
Japan
Telephone
075-753-4494
Fax: 075-753-4409
kuramot@anim.med.kyoto-u.ac.jp
Inbred Generations
F8
Coat Color
Deposition Status
light brown
Embryo
Sperm
Live Animals
Usage Restrictions
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
For a commercial use of this resource, a new contract must be concluded between the depositor and the recipient.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
Origin
A mutant rat was found in the course of inbreeding between a male rat (called TSR Louis) maintained by American breeders of fancy rats (Spoiled Ratten Rattery: SRR) and a PVG female. This rat showed gait abnormality in F3 and the abnormality became prominent in F5. F8 rats showed circling-like abnormality. KFRS is an abbreviation of Kyoto Fancy Rat SRR. (Jul 7, 2009)
Strain Characteristics
Circling.
Breeding Conditions
Maintained by crossing of circling rats. Mutant females are fertile, but have failure of breast feeding, therefore, bad reproducibility. (Jul 7, 2009)
Genotyping
Determined by phenotype.
References
Kuramoto T, Yokoe M, Yagasaki K, Kawaguchi T, Kumafuji K, Serikawa T.
Genetic analyses of fancy rat-derived mutations.
Exp Anim. 2010;59(2):147-55.