Japanese
NBRP Rat No: 0569
Strain Name
:
SD-Tg(CAG-lacZ)541Htsu
Commmon Name: SD-Tg(CALNL-LacZ)541, LacZ541
Principal Investigator
Hiroyuki Tsuda
Organization
Nagoya City University Graduate School of Medical Sciences Department of Molecular Toxicology
Address
1 Kawasumi, Mizuho-cho Mizuho-ku, Nagoya
467-8601 Aichi
Japan
Telephone
052-853-8992
Fax: 052-853-8996
htsuda@med.nagoya-cu.ac.jp
Inbred Generations
Coat Color
Deposition Status
albino (c)
Embryo
Sperm
Live Animals
Usage Restrictions
The recipient of BIOLOGICAL RESOURCE shall obtain prior written consent concerning usage from the DEPOSITOR. The recipient must agree on collaborative research with the DEPOSITOR until publication of literature. This condition is not limited to a two-year period after deposition. After publication, the recipient is requested to cite the literature designated by the DEPOSITOR.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
lacZ: beta-galactosidase, E. coli
Origin
This transgenic rat was originated from SD strain. (Oct 30, 2009) LacZ gene expression is controlled by Cre-loxP system.
Strain Characteristics
The transgene is regulated by the Cre/loxP system. LacZ is driven by CAG promoter. (Oct 30, 2009)
Breeding Conditions
Maintained in homozygous condition. (Oct 30, 2009)
Genotyping
primers: 5'- TCTGGATCAAATCCGAACGC -3' and 5'- TCCTGTAGCCAGCTTTCATC -3’,
product size: bp
References
Fukamachi K, Tanaka H, Sakai Y, Alexander DB, Futakuchi M, Tsuda H, Suzui M.
A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination.
Genesis.2013 ;51(4):268-74