Japanese
NBRP Rat No: 0643
Strain Name
:
ACI.BUF-
Aftm1
/2Mna
Commmon Name: ACI/Mna-Aftm1
Principal Investigator
Mutsushi Matsuyama
Organization
Fujita Health University Department of Virology and Parasitology
Address
1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi
420-1192 Aichi
Japan
Telephone
0562-93-2486
Fax: 0562-93-4008
mmatsuya@fujita-hu.ac.jp
Inbred Generations
F23
Coat Color
Deposition Status
Albino
Embryo
Sperm
Live Animals
Usage Restrictions
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Others
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio- Hypertension
Oncology
Metabolism
Otorhinology
Immunology
Infectious Disease
Osteology
Internal Medicine
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Others
Control Strains
Reporter gene Strains
Gene
遺伝子領域: Aftm1 (Atrophy of fast twitch muscle-1)
Origin
The region of mild atrophy in fast-twitch muscles of BUF/Mna strains, was transferred onto the genetic background of ACI strain. At that time albino mutaion was also transferred because of the adjacent region.
Strain Characteristics
All of this strain develops mild and slowly progressing muscle atrophy with absent, hypoplastic or cystic kidneys on one side in 20 %.
Breeding Conditions
sib mating
Genotyping
References
Amo, H., Matsuyama, M., et al.: Genetic reguration of slowly progressing mild atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve, 20:1528-1263, 1997.