NBRP Rat No: 0643 Strain NameACI.BUF-Aftm1/2Mna Commmon Name: ACI/Mna-Aftm1
 Principal Investigator  Mutsushi Matsuyama
 Organization   Fujita Health University  Department of Virology and Parasitology
 Address  1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi

420-1192 Aichi

 Telephone  0562-93-2486  Fax:  0562-93-4008  mmatsuya@fujita-hu.ac.jp
 Inbred Generations   F23 
 Coat Color
 Deposition Status
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene 遺伝子領域: Aftm1 (Atrophy of fast twitch muscle-1)
 Origin The region of mild atrophy in fast-twitch muscles of BUF/Mna strains, was transferred onto the genetic background of ACI strain. At that time albino mutaion was also transferred because of the adjacent region.
 Strain Characteristics All of this strain develops mild and slowly progressing muscle atrophy with absent, hypoplastic or cystic kidneys on one side in 20 %.
 Breeding Conditions sib mating
 References  Amo, H., Matsuyama, M., et al.: Genetic reguration of slowly progressing mild atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve, 20:1528-1263, 1997.