Rat Strain Information (FOB: Stimulus Response)
Strain Name  ALB/Hok(F) 
Approach Response  2,2,2,2,2,2  
Touch Response  2,2,2,2,2,2  
Eyelid Reflex  2,2,2,2,2,2  
Pinna Reflex  2,2,2,2,2,2  
Sound Response  2,2,2,2,2,2  
Tail Pinch Response  2,2,2,2,2,2  
Pupillary Reflex  2,2,2,2,2,2  
Righting Reflex  1,1,1,1,1,1  
 

Stimulus response

1) Approach response: Slowly move the tip of a dull object (e.g., tweezers) up to 2-3 cm in front of the animal and hold there for 4 seconds. Choose the item from the following list that best describes the animal's reaction to the dull object (scored).


1: No reaction
2: Slowly approaches, sniffs and pulls back/normal
3: Twitches (muscular tenseness)
4: Exhibits a violent overreaction such as jumping, biting, squeaking or attack


2) Touch response: Choose the item from the following list that best describes the animal's reaction to being gently touched on the abdomen with a dull object (e.g., tweezers) (scored).


1: No reaction
2: Slowly retreats/normal
3: Twitches (muscular tenseness)
4: Exhibits a violent overreaction such as jumping, biting, squeaking or attack


3) Eyelid reflex: Choose the item from the following list that best describes the animal's reflex upon being touched on the eyelid with a dull object (e.g., tweezers) (scored).


1: Does not blink
2: Blinks/normal


4) Pinna reflex: Choose the item from the following list that best describes the animal's twitch reflex upon being touched on the auricle with a dull object (e.g., tweezers) (scored).


1: Auricle does not twitch
2: Auricle twitches/normal


5) Sound response: Choose the item from the following list that best describes the twitch reflex of the animal's body upon having a clicker sounded approximately 5 cm from its back (scored).


1: No reaction
2: Mild reaction, hears sound/normal
3: Twitches (muscular tension)


6) Tail pinch response: Choose the item from the following list that best describes the animal's response to pain upon having the base of its tail squeezed with tweezers or a similar implement (scored).


1: No reaction
2: Looks back, moves forward and lightly squeaks/normal
3: Twitches (muscular tension)
4: Exhibits a violent overreaction such as jumping, biting, squeaking or attack


7) Pupillary reflex: Shine a penlight in the animal's eyes (scored).


1: Does not contract
2: Contracts


8) Righting reflex: Choose the item from the following list that best describes the animal's response to being dropped, belly up, from a height of 30 cm. Skip if animal is paralyzed or in an extremely poor state (scored).


1: Lands on four limbs/normal
2: All limbs do not touch at once
3: Lands on side
4: Lands on back