| 由来: |
バックグラウンド系統：Long-Evans （Iar:Long-Evans, 動物繁殖研究所）
導入した遺伝子の詳細：本ラットはマウスPvalb遺伝子の第2エキソン部分にcre遺伝子を挿入した改変BACをLong-Evansラット受精卵にインジェクションして作製した。
BACの詳細な情報（参考文献）： Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice. Tanahira C, Higo S, Watanabe K, Tomioka R, Ebihara S, Kaneko T, Tamamaki N. Neurosci Res. 2009 Mar;63(3):213-23. doi: 10.1016/j.neures.2008.12.007. Epub 2009 Jan 9. PMID:19167436 |
| 参考文献: |
N Matsushita, S Kato, K Nishizawa, M Sugawara, K Takeuchi, Y Miyasaka, T Mashimo, K Kobayashi
Protocol for highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence in rodents
STAR Protoc. 2023 Dec 15;4(4):102667.
N Matsushita, S Kato, K Nishizawa, M Sugawara, K Takeuchi, Y Miyasaka, T Mashimo, K Kobayashi
Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence
Cell Rep Methods. 2023 Jan 18;3(2):100393.
Oh YM, Karube F, Takahashi S, Kobayashi K, Takada M, Uchigashima M, Watanabe M, Nishizawa K, Kobayashi K, Fujiyama F, "Using a novel PV-Cre rat model to characterize pallidonigral cells and their terminations", Brain Struct Funct, 222(5), 2359-2378, 2017 Jul |