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NBRP-Ratを利用した論文

                                   
              
Last Update: Mach. 27, 2025
                                   
           

2025

Koyanagi Y, Yamamoto K, Kitano K, Kajiwara M, Kobayashi M.
Neuronal subtype-dependent kinetics of EPSCs induced by thalamocortical projections from the ventroposteromedial thalamic nucleus to the insular cortex in rats.
Pflugers Arch. 2025 Mar 14. doi: 10.1007/s00424-025-03074-8.

Yokoi N, Adachi N, Hirokoji T, Nakano K, Yoshihara M, Shigenaka S, Urakawa R, Taniguchi Y, Yoshida Y, Yokose S, Suyama M, Okamura T.
Comparative transcriptome and mutation analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene.
DNA Res. 2025 Feb 26:dsaf004. doi: 10.1093/dnares/dsaf004.

Kazuki Morita, Masamichi Nakayama, Jiacheng Wang, Satoru Onizuka, Masahiro Hatasa, Yujin Ohsugi, Yosuke Tsuchiya, Hiromi Niimi, Anhao Liu, Hideaki Sakai, Teruo Okano, Takanori Iwata
Stable preparation of in vivo transplantable periodontal ligament-derived mesenchymal stem cell sheets in thermoresponsive culture dishes with tunable cell detachability
Regen Ther. 2025 Jan 13:28:345-357. doi: 10.1016/j.reth.2025.01.004. eCollection 2025 Mar.

Dwinell MR, Takizawa A, Tutaj M, Malloy L, Schilling R, Endsley A, Demos WM, Smith JR, Wang SJ, De Pons J, Kundurthi A, Geurts AM, Kwitek AE.
Establishing the hybrid rat diversity program: a resource for dissecting complex traits.
Mamm Genome. 2025 Mar;36(1):25-37. doi: 10.1007/s00335-024-10102-y. Epub 2025 Feb 5.

Daichi Sueto, Eriko I, Akihisa Onishi, Makoto Tsuda
Spinal dorsal horn neurons involved in the alleviating effects of cannabinoid receptor agonists on neuropathic allodynia-like behaviors in rats
J Pharmacol Sci. 2025 Apr;157(4):253-260. doi: 10.1016/j.jphs.2025.02.008. Epub 2025 Feb 22.

Ishida S, Taguchi K, Iida R, Hattori K, Taketsuru H, Yoshimi K, Yamamoto M, Mashimo T.
Diverse Cre recombinase expression pattern in Albumin-Cre driver rats.
Exp Anim. 2025 Jan 22. doi: 10.1538/expanim.24-0174.

2024

Yoshimi K, Kuno A, Yamauchi Y, Hattori K, Taniguchi H, Mikamo K, Iida R, Ishida S, Goto M, Takeshita K, Ito R, Takahashi R, Takahashi S, Mashimo T.
Genome editing using type I-E CRISPR-Cas3 in mice and rat zygotes.
Cell Rep Methods. 2024 Aug 19;4(8):100833. doi: 10.1016/j.crmeth.2024.100833.

Kim JI, Lim HJ, Kwon E, Mashimo T, Kang BC.
Immune deficiency phenotypes of Il2rg, Rag2 or Il2rg/Rag2 double knockout rats; establishment of human leukemia xenograft models.
Lab Anim Res. 2024 Dec 27;40(1):43. doi: 10.1186/s42826-024-00231-5.

Mizuno-Iijima S, Kawamoto S, Asano M, Mashimo T, Wakana S, Nakamura K, Nishijima KI, Okamoto H, Saito K, Yoshina S, Miwa Y, Nakamura Y, Ohkuma M, Yoshiki A.
Mammalian genome research resources available from the National BioResource Project in Japan.
Mamm Genome. 2024 Dec;35(4):497-523. doi: 10.1007/s00335-024-10063-2. Epub 2024 Sep 11.

Sato T, Takahashi I, Watanabe Y, Yokoyama D, Shimokawa N.
Congenital kyphoscoliosis: Analysis of vertebral abnormalities using model animals (Review).
Exp Ther Med. 2024 Sep 4;28(5):416. doi: 10.3892/etm.2024.12705. eCollection 2024 Nov.

Ashenagar MS, Higashino T, Matsumoto A, Higashino H.
Mechanisms of thiazide-induced hypertension treatment: insights from gene expression and histological analysis in malignant stroke-prone spontaneously hypertensive rats.
J Hypertens. 2024 Dec 1;42(12):2084-2093. doi: 10.1097/HJH.0000000000003837. Epub 2024 Aug 21.

Tadokoro T, Murata S, Kato M, Ueno Y, Tsuchida T, Okumura A, Kuse Y, Konno T, Uchida Y, Yamakawa Y, Zushi M, Yajima M, Kobayashi T, Hasegawa S, Kawakatsu-Hatada Y, Hayashi Y, Osakabe S, Maeda T, Kimura K, Mori A, Tanaka M, Kamishibahara Y, Matsuo M, Nie YZ, Okamoto S, Oba T, Tanimizu N, Taniguchi H.
Human iPSC-liver organoid transplantation reduces fibrosis through immunomodulation.
Sci Transl Med. 2024 Jul 24;16(757):eadg0338. doi: 10.1126/scitranslmed.adg0338. Epub 2024 Jul 24.

Takeda S, Hoshiai R, Tanaka M, Izawa T, Yamate J, Kuramoto T, Kuwamura M.
Myelin lesion in the aspartoacylase (Aspa) knockout rat, an animal model for Canavan disease.
Exp Anim. 2024 Jul 9;73(3):347-356. doi: 10.1538/expanim.23-0089. Epub 2024 Mar 28.

Yamada K, Mano T, Hazim S, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H.
Neonatal aromatase inhibition blocked defeminization of AVPV Kiss1 neurons and LH surge-generating system in male rats.
Endocrinology. 2024 Feb 20;165(4):bqae028. doi: 10.1210/endocr/bqae028.

Gima S, Oe K, Nishimura K, Ohgita T, Ito H, Kimura H, Saito H, Takata K.
Host-to-graft propagation of inoculated α-synuclein into transplanted human induced pluripotent stem cell-derived midbrain dopaminergic neurons.
Regen Ther. 2024 Jan 6:25:229-237. doi: 10.1016/j.reth.2023.12.019. eCollection 2024 Mar.

Sueto D, Onishi A, I E, Yoshikawa Y, Tsuda M.
Laminar-selective spinal astrocyte population capable of converting tactile information into nociceptive in rats.
J Pharmacol Sci. 2024 Apr;154(4):312-315. doi: 10.1016/j.jphs.2024.02.014. Epub 2024 Feb 27.

Uchimura Y, Hino K, Hattori K, Kubo Y, Owada A, Kimura T, Sugawara L, Kume S, Bellier JP, Yanagisawa D, Shiino A, Nakayama T, Daigo Y, Mashimo T, Udagawa J.
Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume.
PLoS One. 2024 Aug 28;19(8):e0309461. doi: 10.1371/journal.pone.0309461. eCollection 2024.

Tanaka M, Fujikawa R, Sekiguchi T, Hernandez J, Johnson OT, Tanaka D, Kumafuji K, Serikawa T, Hoang Trung H, Hattori K, Mashimo T, Kuwamura M, Gestwicki JE, Kuramoto T.
A missense mutation in the Hspa8 gene encoding heat shock cognate protein 70 causes neuroaxonal dystrophy in rats.
Front Neurosci. 2024 Feb 6:18:1263724. doi: 10.3389/fnins.2024.1263724. eCollection 2024.

Hayashi Y, Ohnishi H, Kitano M, Kishimoto Y, Takezawa T, Okuyama H, Yoshimatsu M, Kuwata F, Tada T, Mizuno K, Omori K.
Comparative study of immunodeficient rat strains in engraftment of hiPSC-derived airway epithelia.
Tissue Eng Part A. 2024 Feb;30(3-4):144-153. doi: 10.1089/ten.TEA.2023.0214. Epub 2023 Dec 20.

2023

Nagae M, Yamada K, Enomoto Y, Kometani M, Tsuchida H, Panthee A, Nonogaki M, Matsunaga N, Takizawa M, Matsuzaki S, Hirabayashi M, Inoue N, Tsukamura H, Uenoyama Y.
Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats.
Sci Rep. 2023 Nov 22;13(1):20495. doi: 10.1038/s41598-023-47222-5.

Takashima M, Taniguchi K, Nagaya M, Yamamura S, Takamura Y, Inatani M, Oki M.
Gene profiles and mutations in the development of cataracts in the ICR rat model of hereditary cataracts.
Sci Rep. 2023 Oct 24;13(1):18161. doi: 10.1038/s41598-023-45088-1.

Takahashi I, Watanabe Y, Sonoda H, Tsunoda D, Amano I, Koibuchi N, Iizuka H, Shimokawa N.
Calcium sensing and signaling are impaired in the lumbar spine of a rat model of congenital kyphosis.
Eur Spine J. 2023 Oct;32(10):3403-3412. doi: 10.1007/s00586-023-07877-0. Epub 2023 Aug 9.

Yamada K, Nagae M, Mano T, Tsuchida H, Hazim S, Goto T, Sanbo M, Hirabayashi M, Inoue N, Uenoyama Y, Tsukamura H.
Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats.
J Reprod Dev. 2023 Oct 20;69(5):227-238. doi: 10.1262/jrd.2023-019. Epub 2023 Jul 28.

Oyagi S, Nakamura R, Katsuno T, Sogami T, Kawai Y, Kishimoto Y, Omori K.
Local coordination of epithelial planar polarity in the maintenance and regeneration of the adult rat airway.
Cell Tissue Res. 2023 Oct;394(1):163-175. doi: 10.1007/s00441-023-03809-y. Epub 2023 Jul 18.

Terada K, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Oka S, Ukai R, Yokoyama T, Iizuka Y, Sakai T, Fukumura S, Tsugawa T, Kocsis JD, Honmou O.
Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury.
Pediatr Res. 2023 Dec;94(6):1921-1928. doi: 10.1038/s41390-023-02717-9. Epub 2023 Jul 8.

Kinboshi M, Shimizu S, Tokudome K, Mashimo T, Serikawa T, Ito H, Takahashi R, Ikeda A, Ohno Y.
Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats.
Heliyon. 2023 Jul 5;9(7):e17984. doi: 10.1016/j.heliyon.2023.e17984. eCollection 2023 Jul.

Sung SY, Lin YW, Wu CC, Lin CY, Hsu PS, Periasamy S, Nagarajan B, Hsieh DJ, Tsai YT, Tsai CS, Lin FY.
Supercritical carbon dioxide-decellularized arteries exhibit physiologic-like vessel regeneration following xenotransplantation in rats.
Biomater Sci. 2023 Mar 28;11(7):2566-2580.

Abe M, Nakatsukasa E, Natsume R, Hamada S, Sakimura K, Watabe AM, Ohtsuka T.
A novel technique for large-fragment knock-in animal production without ex vivo handling of zygotes.
Sci Rep. 2023 Feb 8;13(1):2245. doi: 10.1038/s41598-023-29468-1.

Hieu HT, Tanaka M, Kuwamura M, Mashimo T, Serikawa T, Kuramoto T.
The rat Downunder (Du) coat color mutation is associated with eye anomalies and embryonic lethality and maps to a 3.9-Mb region on chromosome 3.
Exp Anim. 2023 Feb 21;72(1):88-94.

Kuramoto T.
Positional cloning of rat mutant genes reveals new functions of these genes.
Exp Anim. 2023 Feb 21;72(1):1-8.

2022

Suzuki T, Kadoya K, Endo T, Iwasaki N.
Molecular and Regenerative Characterization of Repair and Non-repair Schwann Cells.
Cell Mol Neurobiol. 2022 Oct 12.

Maeda S, Kawamura T, Sasaki M, Shimamura K, Shibuya T, Harada A, Honmou O, Sawa Y, Miyagawa S.
Intravenous infusion of bone marrow-derived mesenchymal stem cells improves tissue perfusion in a rat hindlimb ischemia model.
Sci Rep. 2022 Oct 10;12(1):16986.

Teraoka S, Honda M, Makishima K, Shimizu R, Tsounapi P, Yumioka T, Iwamoto H, Li P, Morizane S, Hikita K, Hisatome I, Takenaka A.
Early effects of an adipose-derived stem cell sheet against detrusor underactivity in a rat cryo-injury model.
Life Sci. 2022 May 6;301:120604.

Fu Q, Ohnishi S, Suda G, Sakamoto N.
Small-molecule inhibitor cocktail promotes the proliferation of pre-existing liver progenitor cells.
Stem Cell Reports. 2022 Jul 12;17(7):1589-1603.

Zhang X, Malik B, Young C, Zhang H, Larkin D, Liao XH, Refetoff S, Liu M, Arvan P.
Maintaining the thyroid gland in mutant thyroglobulin-induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood.
J Biol Chem. 2022 May 23;102066.

Ishibashi T, Yoshikawa Y, Sueto D, Tashima R, Tozaki-Saitoh H, Koga K, Yamaura K, Tsuda M.
Selective Involvement of a Subset of Spinal Dorsal Horn Neurons Operated by a Prodynorphin Promoter in Aβ Fiber-Mediated Neuropathic Allodynia-Like Behavioral Responses in Rats.
Front Mol Neurosci. 2022 Jun 23;15:911122.

Aragane Y, Higashino T, Kinoshita K, Ashenagar MS, Higashino H.
Hypertension-Associated Genes in the Mesenteric Artery of Three Spontaneously Hypertensive Rat Substrains Identified Using a DNA Array Method.
Front Biosci (Landmark Ed). 2022 Jun 15;27(6):191.

Matsui Y, Kadoya K, Nagano Y, Endo T, Hara M, Matsumae G, Suzuki T, Yamamoto Y, Terkawi MA, Iwasaki N.
IL4 stimulated macrophages promote axon regeneration after peripheral nerve injury by secreting uPA to stimulate uPAR upregulated in injured axons.
Cell Mol Life Sci. 2022 May 10;79(6):289.

Lin YW, Tsai CS, Huang CY, Tsai YT, Shih CM, Lin SJ, Li CY, Lin CY, Sung SY, Lin FY.
Far-Infrared Therapy Decreases Orthotopic Allograft Transplantation Vasculopathy.
Biomedicines. 2022 May 7;10(5):1089.

Lahr CA, Landgraf M, Wagner F, Cipitria A, Moreno-Jiménez I, Bas O, Schmutz B, Meinert C, Cavalcanti ADS, Mashimo T, Miyasaka Y, Holzapfel BM, Shafiee A, McGovern JA, Hutmacher DW.
A humanised rat model of osteosarcoma reveals ultrastructural differences between bone and mineralised tumour tissue.
Bone. 2022 May:158:116018. doi: 10.1016/j.bone.2021.116018. Epub 2021 May 20.

Eguchi S, Kimura K, Kageyama K, Tani N, Tanaka R, Nishio K, Shinkawa H, Ohira GO, Amano R, Tanaka S, Yamamoto A, Takemura S, Yashiro M, Kubo S.
Optimal Organ for Patient-derived Xenograft Model in Pancreatic Cancer and Microenvironment that Contributes to Success.
Anticancer Res. 2022 May;42(5):2395-2404.

Takeshi Tada, Hiroe Ohnishi, Norio Yamamoto, Fumihiko Kuwata, Yasuyuki Hayashi, Hideaki Okuyama, Tsunetaro Morino, Yoshiyuki Kasai, Hiromi Kojima, Koichi Omori.
Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats.
Regen Ther. 2022 Jan 14;19:77-87.

Del-Pozo J, Headon DJ, Glover JD, Azar A, Schuepbach-Mallepell S, Bhutta MF, Riddell J, Maxwell S, Milne E, Schneider P, Cheeseman M.
The EDA deficient mouse has Zymbal's gland hypoplasia and acute otitis externa.
Dis Model Mech. 2022 Mar 1;15(3):dmm049034.

Endo T, Kadoya K, Suzuki T, Suzuki Y, Terkawi MA, Kawamura D, Iwasaki N.
Mature but not developing Schwann cells promote axon regeneration after peripheral nerve injury.
NPJ Regen Med. 2022 Jan 28;7(1):12.

2021

Tabata H, Sasaki M, Kataoka-Sasaki Y, Shinkai N, Ichihara K, Masumori N, Kocsis JD, Honmou O.
Possible role of intravenous administration of mesenchymal stem cells to alleviate interstitial cystitis/bladder pain syndrome in a Toll-like receptor-7 agonist-induced experimental animal model in rat.
BMC Urol. 2021 Nov 13;21(1):156.

Matta A, Karim MZ, Gerami H, Benigno B, Erwin WM.
A comparative study of mesenchymal stem cell transplantation and NTG-101 molecular therapy to treat degenerative disc disease.
Sci Rep. 2021 Jul 20;11(1):14804.

Kiyokazu OZAKI, Yui TERAYAMA, Tetsuro MATSUURA.
Spontaneous cholangiofibrosis adjacent to a dilated common bile duct with intestinal metaplasia in a Royal College of Surgeons rat.
J Toxicol Pathol. 2021 Oct; 34(4): 339–343.

Khan AA, Sundar P, Natarajan B, Gupta V, Arige V, Reddy SS, Barthwal MK, Mahapatra NR.
An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat.
J Mol Cell Cardiol. 2021 Sep;158:140-152.

Sanchez-Aguilera A, Wheeler DW, Jurado-Parras T, Valero M, Nokia MS, Cid E, Fernandez-Lamo I, Sutton N, García-Rincón D, de la Prida An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo.
PLoS Biol. 2021 May 6;19(5):e3001213.

Zhang X, Kellogg AP, Citterio CE, Zhang H, Larkin D, Morishita Y, Targovnik HM, Balbi VA, Arvan P.
Thyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death.
JCI Insight. 2021 Jun 8;6(11):e148496.

Magota H, Sasaki M, Kataoka-Sasaki Y, Oka S, Ukai R, Kiyose R, Onodera R, Kocsis JD, Honmou O.
Intravenous infusion of mesenchymal stem cells delays disease progression in the SOD1G93A transgenic amyotrophic lateral sclerosis rat model.
Brain Res. 2021 Apr 15;1757:147296.

Yoshimatsu M, Ohnishi H, Zhao C, Hayashi Y, Kuwata F, Kaba S, Okuyama H, Kawai Y, Hiwatashi N, Kishimoto Y, Sakamoto T, Ikeya M, Omori K.
In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells.
Stem Cell Res. 2021 Apr;52:102233.

Hladíková Z, Voglová B, Pátíková A, Berková Z, Kříž J, Vojtíšková A, Leontovyč I, Jirák D, Saudek F.
Bioluminescence Imaging In Vivo Confirms the Viability of Pancreatic Islets Transplanted into the Greater Omentum.
Mol Imaging Biol. 2021 Oct;23(5):639-649.

Gallucci AF, Patterson KC, Weit AR, Van Der Pol WJ, Dubois LG, Percy AK, Morrow CD, Campbell SL, Olsen ML.
Microbial community changes in a female rat model of Rett syndrome.
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13;109:110259.

Shinji Kawaguchi, Yusuke Soma, Kazuaki Nakajima, Hideaki Kanazawa, Shugo Tohyama, Ryota Tabei, Akinori Hirano, Noriko Handa, Yoshitake Yamada, Shigeo Okuda, Shuji Hishikawa, Takumi Teratani, Satoshi Kunita, Yoshikazu Kishino, Marina Okada, Sho Tanosaki, Shota Someya, Yuika Morita, Hidenori Tani, Yujiro Kawai, Masataka Yamazaki, Akira Ito, Rei Shibata, Toyoaki Murohara, Yasuhiko Tabata, Eiji Kobayashi, Hideyuki Shimizu, Keiichi Fukuda, Jun Fujita.
Intramyocardial Transplantation of Human iPS Cell–Derived Cardiac Spheroids Improves Cardiac Function in Heart Failure Animals.
JACC Basic Transl Sci. 2021 Feb 19;6(3):239-254.

Hoang Trung H, Yoshihara T, Nakao A, Hayashida K, Hirata Y, Shirasuna K, Kuwamura M, Nakagawa Y, Kaneko T, Mori Y, Asano M, Kuramoto T.
Deficiency of the RIβ subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats.
Sci Rep. 2021 Jan 21;11(1):2039.

Tashima R, Koga K, Yoshikawa Y, Sekine M, Watanabe M, Tozaki-Saitoh H, Furue H, Yasaka T, Tsuda M.
A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior.
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2021220118.

2020

Ishiwata S, Iizuka H, Sonoda H, Tsunoda D, Tajika Y, Chikuda H, Koibuchi N, Shimokawa N.
Upregulated miR-224-5p suppresses osteoblast differentiation by increasing the expression of Pai-1 in the lumbar spine of a rat model of congenital kyphoscoliosis.
Mol Cell Biochem. 2020 Dec;475(1-2):53-62.

Ueta H, Xu XD, Yu B, Kitazawa Y, Yu E, Hara Y, Morita-Nakagawa M, Zhou S, Sawanobori Y, Ueha S, Rokutan K, Tanaka T, Tokuda N, Matsushima K, Matsuno K.
Suppression of liver transplant rejection by anti-donor MHC antibodies via depletion of donor immunogenic dendritic cells.
Published online 2020 Dec 1. Int Immunol. 2021 Apr 22;33(5):261-272.

Yasuda N, Sasaki M, Kataoka-Sasaki Y, Nagahama H, Kocsis JD, Kawaharada N, Honmou O.
Intravenous delivery of mesenchymal stem cells protects both white and gray matter in spinal cord ischemia.
Brain Res. 2020 Nov 15;1747:147040.

Hosoki A, Ogawa M, Nishimura Y, Nishimura M, Daino K, Kakinuma S, Shimada Y, Imaoka T.
The effect of radiation on the ability of rat mammary cells to form mammospheres.
Radiat Environ Biophys. 2020 Nov;59(4):711-721.

Numakura Y, Uemura R, Tanaka M, Izawa T, Yamate J, Kuramoto T, Kaneko T, Mashimo T, Yamamoto T, Serikawa T, Kuwamura M.
PHF24 is expressed in the inhibitory interneurons in rats.
Epub 2020 Oct 29. Exp Anim. 2021 Feb 6;70(1):137-143.

Ohmori I, Kobayashi K, Ouchida M.
Scn1a and Cacna1a mutations mutually alter their original phenotypes in rats.
Neurochem Int. 2020 Dec;141:104859.

Ueda Y, Hirota K, Yamauchi I, Hakata T, Yamashita T, Fujii T, Yasoda A, Inagaki N.
Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect.
PLoS One. 2020 Oct 1;15(10):e0240023.

Ohmichi Y, Ohmichi M, Tashima R, Osuka K, Fukushige K, Kanikowska D, Fukazawa Y, Yawo H, Tsuda M, Naito M, Nakano T.
Physical disuse contributes to widespread chronic mechanical hyperalgesia, tactile allodynia, and cold allodynia through neurogenic inflammation and spino-parabrachio-amygdaloid pathway activation.
Pain. 2020 Aug;161(8):1808-1823.

Miyawaki Y, Samata B, Kikuchi T, Nishimura K, Takahashi J.
Zonisamide promotes survival of human-induced pluripotent stem cell-derived dopaminergic neurons in the striatum of female rats.
J Neurosci Res. 2020 Aug;98(8):1575-1587.

Lin FY, Shih CM, Huang CY, Tsai YT, Loh SH, Li CY, Lin CY, Lin YW, Tsai CS.
Dipeptidyl Peptidase-4 Inhibitor Decreases Allograft Vasculopathy Via Regulating the Functions of Endothelial Progenitor Cells in Normoglycemic Rats.
Cardiovasc Drugs Ther. 2020 Jul 4.

Michael Shur, Florian Fallegger, Elvira Pirondini, Adrien Roux, Arnaud Bichat, Quentin Barraud, Grégoire Courtine, and Stéphanie P. Lacour.
Soft Printable Electrode Coating for Neural Interfaces.
ACS Appl. Bio Mater. 2020, 3, 4388−4397.

Nishitani A, Nagayoshi H, Takenaka S, Asano M, Shimizu S, Ohno Y, Kuramoto T.
Involvement of NMDA receptors in tremor expression in Aspa/Hcn1 double-knockout rats.
Exp Anim. 2020 Nov 12;69(4):388-394.

Takeishi K, Collin de l'Hortet A, Wang Y, Handa K, Guzman-Lepe J, Matsubara K, Morita K, Jang S, Haep N, Florentino RM, Yuan F, Fukumitsu K, Tobita K, Sun W, Franks J, Delgado ER, Shapiro EM, Fraunhoffer NA, Duncan AW, Yagi H, Mashimo T, Fox IJ, Soto-Gutierrez A.
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Cell Rep. 2020 Jun 2;31(9):107711.

Ishida H, Shibata T, Shibata S, Tanaka Y, Sasaki H, Kubo E.
Lutein plus Water Chestnut (Trapa bispinosa Roxb.) Extract Inhibits the Development of Cataracts and Induces Antioxidant Gene Expression in Lens Epithelial Cells.
Biomed Res Int. 2020 May 19;2020:9204620.

Kawakami N, Kobayashi K, Nishimura A, Ohmori I.
Poor mother-offspring relationships in rats with Cacna1a mutation.
Exp Anim. 2020 Apr 24;69(2):153-160.

Ara S, Miyazaki A, Hoang Trung H, Yokoe M, Nakagawa Y, Kaneko T, Kuramoto T.
Long terminal repeat insertion in Kit causes unilateral renal agenesis in rats.
Translat Regulat Sci. 2(1): 30–35, 2020.

Goto T, Miyagawa S, Tamai K, Matsuura R, Kido T, Kuratani T, Shimamura K, Sakaniwa R, Harada A, Sawa Y.
High-mobility group box 1 fragment suppresses adverse post-infarction remodeling by recruiting PDGFRα-positive bone marrow cells.
PLoS One. 2020 Apr 10;15(4):e0230392.

Kim H, Yoshihara M, Suyama M.
Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms.
Mamm Genome. 2020 Apr;31(3-4):86-94.

Yoshitsugu R, Kikuchi K, Hori S, Iwaya H, Hagio M, Shimizu H, Hira T, Ishizuka S.
Correlation between 12α-hydroxylated bile acids and insulin secretion during glucose tolerance tests in rats fed a high-fat and high-sucrose diet.
Lipids Health Dis. 2020 Jan 15;19(1):9.

2019

AF Gallucci, KC Patterson, AR Weit, WJ Van Der Pol, LG Dubois, AK Percy, CD Morrow, SL Campbell and ML Olsen.
Shared microbial community changes in female rats and humans with Rett syndrome.
Research Square. 2019 Arch. Dec 17.

Ikeda K, Igarashi H, Yawo H, Kobayashi K, Arata S, Kawakami K, Izumizaki M, Onimaru H.
Optogenetic analysis of respiratory neuronal networks in the ventral medulla of neonatal rats producing channelrhodopsin in Phox2b-positive cells.
Pflugers Arch. 2019 Oct 20.

Serikawa T, Kunisawa N, Shimizu S, Kato M, Alves Iha H, Kinboshi M, Nishikawa H, Shirakawa Y, Voigt B, Nakanishi S, Kuramoto T, Kaneko T, Yamamoto T, Mashimo T, Sasa M, Ohno Y.
Increased seizure sensitivity, emotional defects and cognitive impairment in PHD finger protein 24 (Phf24)-null rats.
Behav Brain Res. 2019 Sep 2;369:111922.

Kuwamura M, Tanimura S, Hasegawa Y, Hoshiai R, Moriyama Y, Tanaka M, Takenaka S, Nagayoshi H, Izawa T, Yamate J, Kuramoto T, Serikawa T.
Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect.
Brain Res. 2019 Sep 1;1718:169-175.

Katagiri M, Iida K, Ishihara K, Nair D, Harada K, Kagawa K, Seyama G, Hashizume A, Kuramoto T, Hanaya R, Arita K, Kurisu K.
Anti-seizure effect and neuronal activity change in the genetic-epileptic model rat with acute and chronic vagus nerve stimulation.
Epilepsy Res. 2019 Sep;155:106159.

Honda A, Tachibana R, Hamada K, Morita K, Mizuno N, Morita K, Asano M.
Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization.
Sci Rep. 2019 Aug 9;9(1):11571.

Nishitani A, Yoshihara T, Tanaka M, Kuwamura M, Asano M, Tsubota Y, Kuramoto T.
Muscle weakness and impaired motor coordination in Hcn1-deficient rats.
Exp Anim. 2019 Jul 9.

Endo T, Kadoya K, Suzuki Y, Kawamura D, Iwasaki N.
A Novel Experimental Model to Determine the Axon-Promoting Effects of Grafted Cells After Peripheral Nerve Injury.
Front Cell Neurosci. 2019 Jun 28;13:280.

Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Suzuki J, Sasaki Y, Nagahama H, Hashi K, Kocsis JD, Honmou O.
Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model.
Neuroscience. 2019 Jun 1;408:361-377.

Del-Pozo J, MacIntyre N, Azar A, Headon D, Schneider P, Cheeseman M.
Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia.
Dis Model Mech. 2019 Apr 25;12(4).

Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K.
Impaired cortico-striatal excitatory transmission triggers epilepsy.
Nat Commun. 2019 Apr 23;10(1):1917.

Fujihara M, Kaneko T, Inoue-Murayama M.
Vitrification of canine ovarian tissues with polyvinylpyrrolidone preserves the survival and developmental capacity of primordial follicles.
Sci Rep. 2019 Mar 8;9(1):3970.

Liu Y, Ohshiro T, Sakuragi S, Koizumi K, Mushiake H, Ishizuka T, Yawo H.
Optogenetic study of the response interaction among multi-afferent inputs in the barrel cortex of rats.
Sci Rep. 2019 Mar 8;9(1):3917.

Ohta R, Ohmukai H.
Effects of pregnancy experience on ovarian senescence and longevity in Hatano rats bred for high- and low-avoidance learning.
Exp Gerontol. 2019 Mar;117:91-98.

Nishitani A, Kunisawa N, Sugimura T, Sato K, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Asano M, Saito Y, Ohno Y, Kuramoto T.
Loss of HCN1 subunits causes absence epilepsy in rats.
Brain Res. 2019 Mar 1;1706:209-217.

Kinboshi M, Shimizu S, Mashimo T, Serikawa T, Ito H, Ikeda A, Takahashi R, Ohno Y.
Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats.
Int J Mol Sci. 2019 Feb 26;20(5).

Koseki H, Miyata H, Shimo S, Ohno N, Mifune K, Shimano K, Yamamoto K, Nozaki K, Kasuya H, Narumiya S, Aoki T.
Two Diverse Hemodynamic Forces, a Mechanical Stretch and a High Wall Shear Stress, Determine Intracranial Aneurysm Formation.
Transl Stroke Res. 2019 Feb 8.

Shimizu Y, Yanobu-Takanashi R, Nakano K, Hamase K, Shimizu T, Okamura T.
A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats.
Mamm Genome. 2019 Feb;30(1-2):23-33.

Herynek V, Turnovcová K, Gálisová A, Kaman O, Mareková D, Koktan J, Vosmanská M, Kosinová L, Jendelová P.
Manganese-Zinc Ferrites: Safe and Efficient Nanolabels for Cell Imaging and Tracking In Vivo.
ChemistryOpen. 2019 Jan 23;8(2):155-165.

Soma S, Yoshida J, Kato S, Takahashi Y, Nonomura S, Sugimura YK, Ríos A, Kawabata M, Kobayashi K, Kato F, Sakai Y, Isomura Y.
Ipsilateral-Dominant Control of Limb Movements in Rodent Posterior Parietal Cortex.
J Neurosci. 2019 Jan 16;39(3):485-502.

2018

Ohta R, Kojima K.
Hatano rats selectively bred for high- and low-avoidance learning: an overview.
Exp Anim. 2018 Dec 10.

Abe K, Yawo H.
Quantitative study of the somatosensory sensitization underlying cross-modal plasticity.
PLoS One. 2018 Dec 5;13(12):e0208089.

Namioka T, Namioka A, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Kocsis JD, Honmou O.
Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction.
J Neurosurg. 2018 Oct 26.

Tanaka M, Kuramochi M, Nakanishi S, Kuwamura M, Kuramoto T.
Rat polyomavirus 2 infection in a colony of X-linked severe combined immunodeficiency rats in Japan.
J Vet Med Sci. 2018 Sep 13;80(9):1400-1406.

Sinha S, Vohra M, Burma NE, Trang T, Midha R, Macrophages Regulate Schwann Cell Maturation after Nerve Injury.
Cell Rep. 2018 Sep 4;24(10):2561-2572.e6.

Herynek V, Swider E, Sticová E, Pátiková A, Kosinová L, Kříž J, Hájek M, Srinivas M, Jirák D.
A Trimodal Imaging Platform for Tracking Viable Transplanted Pancreatic Islets In Vivo: F-19 MR, Fluorescence, and Bioluminescence Imaging.
Mol Imaging Biol. 2018 Aug 30.

Boateng M, Okai DB, Frimpong YO,Ntim A, Acheampong YS.
Entomophagous Response of Albino Rats to Cockroach (Periplaneta Americana) Meal.
Open Agriculture 2018 Aug 22.

Sakai T, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Fukumura S, Kobayashi M, Tsutsumi H, Kocsis JD, Honmou O.
Functional recovery after the systemic administration of mesenchymal stem cells in a rat model of neonatal hypoxia-ischemia.
J Neurosurg Pediatr. 2018 Aug 3.

Ohno T, Kai T, Miyasaka Y, Maruyama H, Ishih A, Kino H.
Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta.
Parasitol Int. 2018 Aug;67(4):357-361.

Niiya K, Ohara H, Isono M, Sheikh AM, Matsuo H, Fujikawa K, Isomura M, Kato N, Nabika T.
Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat.
Sci Rep. 2018 Jun 20;8(1):9403.

Laulederkind SJF, Hayman GT, Wang SJ, Smith JR, Petri V, Hoffman MJ, De Pons J, Tutaj MA, Ghiasvand O, Tutaj M, Thota J, Dwinell MR, Shimoyama M.
A Primer for the Rat Genome Database (RGD).
Methods Mol Biol. 2018;1757:163-209.

Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T.
CLICK: one-step generation of conditional knockout mice.
BMC Genomics. 2018 May 2;19(1):318

Ueta H, Kitazawa Y, Sawanobori Y, Ueno T, Ueha S, Matsushima K, Matsuno K.
Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.
Int Immunol. 2018 Mar 8;30(2):53-67.

Tashima R, Koga K, Sekine M, Kanehisa K, Kohro Y, Tominaga K, Matsushita K, Tozaki-Saitoh H, Fukazawa Y, Inoue K, Yawo H, Furue H, Tsuda M.
Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-like Sensory and Emotional Behaviors after Nerve Injury in Rats.
eNeuro. 2018 Feb 15;5(1).

2017

Gálisová A, Fábryová E, Sticová E, Kosinová L, Jirátová M, Herynek V, Berková Z, Kříž J, Hájek M, Jirák D.
The Optimal Timing for Pancreatic Islet Transplantation into Subcutaneous Scaffolds Assessed by Multimodal Imaging.
Contrast Media Mol Imaging. 2017 Dec 26;2017:5418495

Matsuda Y, Sasaki M, Kataoka-Sasaki Y, Takayanagi A, Kobayashi K, Oka S, Nakazaki M, Masumori N, Kocsis JD, Honmou O.
Intravenous Infusion of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats.
Sex Med. 2017 Dec 20. pii: S2050-1161(17)30097-1. [Epub ahead of print]

Abe K, Yawo H.
Optogenetic conditioning of paradigm and pattern discrimination in the rat somatosensory system.
PLoS One. 2017 Dec 21;12(12):e0189439.

Zabielski P, Błachnio-Zabielska AU, Wójcik B, Chabowski A, Górski J.
Effect of plasma free fatty acid supply on the rate of ceramide synthesis in different muscle types in the rat.
PLoS One. 2017 Nov 2;12(11):e0187136.

Yoshimi K, Mashimo T.
Application of genome editing technologies in rats for human disease models.
J Hum Genet. 2017 Nov 20.

Lee W, Kim D, Matsuhisa N, Nagase M, Sekino M, Malliaras GG, Yokota T, Someya T.
Transparent, conformable, active multielectrode array using organic electrochemical transistors.
Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201703886

Jimbo Y, Matsuhisa N, Lee W, Zalar P, Jinno H, Yokota T, Sekino M, Someya T.
Ultraflexible Transparent Oxide/Metal/Oxide Stack Electrode with Low Sheet Resistance for Electrophysiological Measurements.
ACS Appl Mater Interfaces. 2017 Oct 11;9(40):34744-34750.

Nohmi T, Masumura K, Toyoda-Hokaiwado N.
Transgenic rat models for mutagenesis and carcinogenesis.
Genes Environ. 2017 Feb 1;39:11.

Kuramoto T, Voigt B, Nakanishi S, Kitada K, Nakamura T, Wakamatsu K, Yoshihara M, Suyama M, Uemura R, Tanaka M, Kuwamura M, Shimizu S, Ohno Y, Sasa M, Serikawa T.
Identification of candidate genes for generalized tonic-clonic seizures in Noda epileptic rat.
Behav Genet. 2017

Saito Y, Sugimura T, Yanagawa Y.
Comparisons of Neuronal and Excitatory Network Properties between the Rat Brainstem Nuclei That Participate in Vertical and Horizontal Gaze Holding.
eNeuro 4 September 2017, ENEURO.0180-17.2017

Kuramoto T, Yokoe M, Kunisawa N, Ohashi K, Miyake T, Higuchi Y, Yoshimi K, Mashimo T, Tanaka M, Kuwamura M, Kaneko S4, Shimizu S, Serikawa T, Ohno Y.
Tremor dominant Kyoto (Trdk) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca2+-activated K+ channel.
Brain Res. 2017. 1676: 38-45

Shimoyama M, Smith R. J, Bryda E, Kuramoto T, Saba L, and Dwinell M.
Rat Genome and Model Resources.
ILAR Journal, 2017, Vol. 58, No. 1, 42–58.

Meek S, Mashimo T, Burdon T.
From engineering to editing the rat genome.
Mamm Genome. 2017 Jul 27. [Epub ahead of print]

Esmaeili R, Sadeghpour A, Darbandi-Azar A, Majidzadeh-A K, Vajhi A, Sadeghizadeh M.
Echocardiographic assessment of myocardial infarction: comparison of a rat model in two strains.
Iran J Vet Res. 2017 Winter;18(1):30-35.

Ohno Y, Tokudome K.
Therapeutic role of synaptic vesicle glycoprotein 2A (SV2A) in modulating epileptogenesis.
CNS Neurol. Disord. Drug Targets, 16:463-471, 2017.

Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo.
BMC Genet. 2017 Mar 29;18(1):29.

Kaizawa Y, Kakinoki R, Ikeguchi R, Ohta S, Noguchi T, Takeuchi H, Oda H, Yurie H, Matsuda S.
A Nerve Conduit Containing a Vascular Bundle and Implanted With Bone Marrow Stromal Cells and Decellularized Allogenic Nerve Matrix.
Cell Transplant. 2017 Feb 16;26(2):215-228.

Rigatti LH, Toptan T, Newsome JT, Moore PS, Chang Y.
Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay.
mSphere. 2016 Dec 21;1(6). pii: e00334-16.

Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Namioka T, Namioka A, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O.
Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats.
J Neurosurg. 2017 Jan 6:1-10.

2016

Syaidah R, Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kikuchi M, Yashiro T.
Fibromodulin Expression in Folliculostellate Cells and Pericytes Is Promoted by TGFβ Signaling in Rat Anterior Pituitary Gland.
Acta Histochem Cytochem. 2016 Dec 28; 49 (6): 171–179.

Shimotsuma Y, Tanaka M, Izawa T, Yamate J, Kuwamura M.
Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats.
PLoS One. 2016 Dec 15;11(12):e0168250.

Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155–157.

Morita T, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Oka S, Oshigiri T, Takebayashi T, Yamashita T, Kocsis JD, Honmou O.
Intravenous infusion of mesenchymal stem cells promotes functional recovery in a model of chronic spinal cord injury.
Neuroscience. 2016 Oct 29;335:221-31.

Nakanishi S, Kuramoto T, Kashiwazaki N, Yokoi N.
Genetic profiling of two phenotypically distinct outbred rats derived from a colony of the Zucker fatty rats maintained at the Tokyo Medical University.
Exp Anim. 2016 Oct 31. [Epub ahead of print]

Patterson KC, Hawkins VE, Arps KM, Mulkey DK, Olsen ML.
MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats.
Hum Mol Genet. 2016 Jun 21. pii: ddw179 [Epub ahead of print]

Terayama Y, matsuura T, Ozaki K.
Malignant mast cell tumor of the thymus in a Royal College of Surgeons (RCS) rat.
J Toxicol Pathol. Article ID: 2016-0044

Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Suzuki J, Tateyama D, Oka S, Namioka T, Namioka A, Onodera R, Mikami T, Wanibuchi M, Kakizawa M, Ishiai S, Kocsis JD, Honmou O.
Synergic Effects of Rehabilitation and Intravenous Infusion of Mesenchymal Stem Cells After Stroke in Rats.
Phys Ther. 2016 May 12. [Epub ahead of print]

Tokudome K, Okumura T, Terada R, Shimizu S, Kunisawa N, Mashimo T, Serikawa T, Sasa M, Ohno Y.
A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release.
Front Pharmacol. 2016 Jul 14;7:210.

Lee W, Kim D, Rivnay J, Matsuhisa N, Lonjaret T, Yokota T, Yawo H, Sekino M, Malliaras G.G and Someya T.
Integration of Organic Electrochemical and Field-Effect Transistors for Ultra flexible, High Temporal Resolution Electrophysiology Arrays.
Adv. Mater. 2016, DOI: 10.1002/adma.201602237

Nagaki Y, Ito K, Kuwahara M.
WTC rat has unique characteristics such as resistant to streptozotocin.
Biochemistry and Biophysics Reports, Volume 8, December 2016, Page 157–161

Yoshihara M, Saito D, Sato T, Ohara O, Kuramoto T, Suyama M.
Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat. BMC Genomics. 2016 Aug 9;17:593.

Gálisová A, Fábryová E, Jirák D, Sticová E, Lodererová A, Herynek V, Kříž J, Hájek M.
Imaging Reveals Improvement of Blood Supply to an Artificial Cell Transplant Site Induced by Bioluminescent Mesenchymal Stem Cells.
Mol Imaging Biol. 2016 Jul 27. [Epub ahead of print].

Taketsuru H, Kaneko T.
In vitro maturation of immature rat oocytes under simple culture conditions and subsequent developmental ability.
J Reprod Dev. 2016 Jul 2. [Epub ahead of print]

Tokudome K, Okumura T, Shimizu S, Mashimo T, Takizawa A, Serikawa T, Terada R, Ishihara S, Kunisawa N, Sasa M, Ohno Y.
Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission.
Sci Rep. 2016 Jun 6;6:27420.

Katsukawa M, Nakajima Y, Fukumoto A, Doi D, Takahashi J.
Fail-safe therapy by gamma-ray irradiation against tumor formation by human induced pluripotent stem cell-derived neural progenitors.
Stem Cells Dev. 2016 Jun 1;25(11):815-25.

Nishimura K, Doi D, Samata B, Murayama S, Tahara T, Onoe H, Takahashi J.
Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1.
Stem Cell Reports. 2016 Apr 12;6(4):511-24.

Katsukawa M, Nakajima Y, Fukumoto A, Doi D, Takahashi J.
Fail-safe therapy by gamma-ray irradiation against tumor formation by human induced pluripotent stem cell-derived neural progenitors.
Stem Cells Dev. 2016 Apr 8. [Epub ahead of print]

Nishitani A, Tanaka M, Shimizu S, Kunisawa N, Yokoe M, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Kuwamura M, Takenaka S, Ohono Y, Kuramoto T.
Involvement of aspartoacylase in tremor expression in rats.
Exp Anim. 2016 Mar 30. [Epub ahead of print]1

Marsan E, Ishida S, Schramm A, Weckhuysen S, Muraca G, Lecas S, Liang N, Treins C, Pende M, Roussel D, Le Van Quyen M, Mashimo T, Kaneko T, Yamamoto T, Sakuma T, Mahon S, Miles R, Leguern E, Charpier S, Baulac S.
Depdc5 knockout rat: A novel model of mTORopathy.
Neurobiol Dis. 2016 Feb 9. pii: S0969-9961(16)30031-6.

Yoshimi K, Kunihiro Y, Kaneko T, Nagahora H, Voigt B, Mashimo T.
ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.
Nat Commun. 2016 Jan 20;7:10431

Tsunoda D, Iizuka H, Ichinose T, Iizuka Y, Mieda T, Shimokawa N, Takagishi K, Koibuchi N.
The Trk family of neurotrophin receptors is downregulated in the lumbar spines of rats with congenital kyphoscoliosis.
Mol Cell Biochem. 2016 Jan;412(1-2):11-8.

Labedz-Maslowska A, Kamycka E, Bobis-Wozowicz S, Madeja Z, Zuba-Surma EK.
Identification of new rat bone marrow- derived population of very small stem cell with Oct-4A and Nanog expression by flow cytometric platforms.
Stem Cells Int. 2016;2016:5069857.

Maeda H, Okamoto K, Namikawa T, Tsuda M, Uemura S, Shiga M, Hanazaki K, Kobayashi M.
Re-evaluation of hepatocyte replacement by recipient-derived cells after allogenic liver transplantation: Discrepancy between clinical observations and a rat model.
Hepatol Res. 2016 Jan 4. [Epub ahead of print]

2015

Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO.
Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits.
Front Neurosci. 2015; 9: 487.

Degro CE, Kulik A, Booker SA, Vida I.
Compartmental distribution of GABAB receptor-mediated currents along the somatodendritic axis of hippocampal principal cells.
Front Synaptic Neurosci. 2015 Mar 23;7:6.

Ohta R, Kumagai F, Marumo H, Usumi K, Saito Y, Kuwagata M.
Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female rats)
Journal of Toxicologic Pathology Article ID: 2015-0045

Tsunoda D, Iizuka H, Ichinose T, Iizuka Y, Mieda T, Shimokawa N, Takagishi K, Koibuchi N.
The Trk family of neurotrophin receptors is downregulated in the lumbar spines of rats with congenital kyphoscoliosis.
Mol Cell Biochem. 2015 Nov 7. [Epub ahead of print]

Kuramoto T, Yokoe M, Tanaka D, Yuri A, Nishitani A, Higuchi Y, Yoshimi K, Tanaka M, Kuwamura M, Hiai H, Kabashima K, Serikawa T.
Atopic dermatitis-like skin lesions with IgE hyperproduction and pruritus in KFRS4/Kyo rats.
J Dermatol Sci. 2015 Nov;80(2):116-23.

Abe K, Takamatsu N, Ishikawa K, Tsurumi T, Tanimoto S, Sakurai Y, Lisse T, Imai K, Serikawa T, Mashimo T.
Novel ENU-Induced Mutation in Tbx6 Causes Dominant Spondylocostal Dysostosis-Like Vertebral Malformations in the Rat.
PLoS One. 2015 Jun 19;10(6):e0130231.

Leow SN, Luu CD, Hairul Nizam MH, Mok PL, Ruhaslizan R, Wong HS, Wan Abdul Halim WH, Ng MH, Ruszymah BH, Chowdhury SR, Bastion ML, Then KY.
Safety and Efficacy of Human Wharton's Jelly-Derived Mesenchymal Stem Cells Therapy for Retinal Degeneration.
PLoS One. 2015 Jun 24;10(6):e0128973.

                                                                                                                                                                                               

                                                                                                                                                                                                            Tomita K, Nishibayashi A, Yano K, Hosokawa K.
                                                                     Adipose-derived stem cells protect against endoneurial cell death: Cell therapy for nerve autografts.
                                                                     Microsurgery. 2015 Jul 20 [Epub ahead of print]                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Labedz-Maslowska A, Kamycka E, Bobis-Wozowicz S, Madeja Z, Zuba-Surma EK.                                                                                                                                        
                                                                                                                                                                                                            Identification of new rat bone marrow- derived population of very small stem                                                                                                                                         cell with Oct-4A and Nanog expression by flow cytometric platforms.
                                                                     Stem Cells International, Article ID 531098                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Ebihara C, Ebihara K, Aizawa-Abe M, Mashimo T, Tomita T, Zhao M, Gumbilai V,                                                                                                                                         Kusakabe T, Yamamoto Y, Aotani D, Yamamoto-Kataoka S, Sakai T, Hosoda K,                                                                                                                                         Serikawa T, Nakao K.
                                                                     Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis.                                                                                                                                        
                                                                                                                                                                                                            Hum Mol Genet. 2015 Aug                                                                                                                                         1;24(15):4238-49.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A.
                                                                     2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.
                                                                     J Cardiovasc Transl Res. 2015 Jun;8(4):269-277.

                                                                                                                                                                                               

                                                                                                                                                                                                            Yamashita, A., Morioka, M., Yahara, Y., Okada, M., Kobayashi, T., Kuriyama, S.,                                                                                                                                                                                                             Matsuda, S., and Tsumaki, N.
                                                                     Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs.                                                                                                                                        
                                                                                                                                                                                                            Stem Cell Reports. 2015                                                                                                                                         Mar 10;4(3):404-418

                                                                                                                                                                                               

                                                                                                                                                                                                            Y. Ohno, S. Shimizu, A. Tatara, T. Imaoku, T. Ishii, M. Sasa, T. Serikawa, T.                                                                                                                                         Kuramoto.
                                                                     Hcn1 is a tremorgenic genetic component in a rat model of essential tremor.                                                                                                                                        
                                                                                                                                                                                                            PLoS One. 2015 May                                                                                                                                         13;10(5):e0123529.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Samata B, Kikuchi T, Miyawaki Y, Morizane A, Mashimo T, Nakagawa M, Okita K,                                                                                                                                         Takahashi J.
                                                                     X-linked severe combined immunodeficiency (X-SCID) rats for xeno-transplantation and behavioral evaluation.
                                                                     J Neurosci Methods. 2015 Mar 30;243:68-77

                                                                                                                                                                                               

                                                                                                                                                                                                            Serikawa T, Mashimo T, Kuramoto T, Voigt B, Ohno Y, Sasa M.
                                                                     Advances on Genetic Rat Models of Epilepsy.
                                                                     Exp Anim. 2015 Feb 5;64(1):1-7.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Nakanishi S, Serikawa T, Kuramoto T.
                                                                     Slc:Wistar Outbred Rats Show Close Genetic Similarity with F344 Inbred Rats.
                                                                     Exp Anim. 2015 Feb 5;64(1):25-9.

                                                                                                                                                                                               

                                                                                                                                                                                                            Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Liu W, Smith JR, Nigam R, Dwinell                                                                                                                                                                                                             MR, Shimoyama M.
                                                                     PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease.
                                                                     Database (Oxford). 2015 Jan 28;2015.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Matsuyama M, Kato K.
                                                                     Refusal of Food Ingestion of Old Male BUF/Mna Rats in Metabolic Cages.
                                                                     Research in Psychology and Behavioral Sciences 3, no. 1 (2015): 5-6.

                                                                                                                                                                                               

                                                                                                                                                                                                            2014

                                                                                                                                                                                               

                                                                                                                                                                                                            Mohammad Rafiqul ISLAM, Jafri Malin ABDULLAH.
                                                                     Age-dependent Electroencephalographic Differences in the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) Model of Absence Epilepsy.
                                                                     Malays J Med Sci. 2014 Dec; 21(Spec Issue): 34-40.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Clement LC, Macé C, Avila-Casado C, Joles JA3, Kersten S, Chugh SS.
                                                                     Circulating Angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome.
                                                                     Nat Med. 2014 Jan;20(1):37-46.

                                                                                                                                                                                               

                                                                                                                                                                                                            Kaneko T, Mashimo T.
                                                                     Creating Knockout and Knockin Rodents Using Engineered Endonucleases via Direct Embryo Injection.
                                                                     Methods Mol Biol. 2015;1239:307-15.

                                                                                                                                                                                               

                                                                                                                                                                                                            Irving AA, Yoshimi K, Hart ML, Parker T, Clipson L, Ford MR, Kuramoto T, Dove                                                                                                                                         WF, Amos-Landgraf JM.
                                                                     The utility of Apc-mutant rats in modeling human colon cancer.
                                                                     Dis Model Mech. 2014 Nov;7(11):1215-1225.

                                                                                                                                                                                               

                                                                                                                                                                                                            Yoshimasu T, Kuramoto T, Kaminaka C, Kanazawa N, Yamamoto Y, Furukawa F.
                                                                     Efficacy of 0.1% adapalene in a non-inflammatory Kyoto Rhino Rat acne model.
                                                                     J Dermatol Sci. 2014 Nov;76(2):143-8.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Shimoyama M, De Pons J, Hayman GT, Laulederkind SJ, Liu W, Nigam R, Petri V,                                                                                                                                         Smith JR, Tutaj M, Wang SJ, Worthey E, Dwinell M, Jacob H.
                                                                     The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease.
                                                                     Nucleic Acids Res. 2014 Oct 29.

                                                                                                                                                                                               

                                                                                                                                                                                                            Serikawa T, Mashimo T, Kuramoto T, Voigt B, Ohno Y, Sasa M.
                                                                     Advances on Genetic Rat Models of Epilepsy.
                                                                     Exp Anim. 2014 Oct 14. [Epub ahead of print]

                                                                                                                                                                                               

                                                                                                                                                                                                            Kaneko T, Sakuma T, Yamamoto T, Mashimo T.
                                                                     Simple knockout by electroporation of engineered endonucleases into intact rat embryos.
                                                                     Sci Rep. 2014 Oct 1;4:6382.

                                                                                                                                                                                               

                                                                                                                                                                                                            Yamagata K, Yamamoto M, Kawakami K, Ohara H, Nabika T.
                                                                     Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
                                                                     Neuroscience. 2014 May 16;267:277-85.

                                                                                                                                                                                               

                                                                                                                                                                                                            Ohmori I, Kawakami N, Liu S, Wang H, Miyazaki I, Asanuma M, Michiue H, Matsui H,                                                                                                                                                                                                             Mashimo T, Ouchida M.
                                                                     Methylphenidate improves learning impairments and hyperthermia-induced seizures caused by an Scn1a mutation.
                                                                     Epilepsia. 2014 Oct;55(10):1558-67.

                                                                                                                                                                                               

                                                                                                                                                                                                            Takano M, Ogawa E, Saitou T, Yamaguchi Y, Asano Y, Serikawa T, Kuramoto T.
                                                                     Morphological features of adult rats of IS/Kyo and IS-Tlk/Kyo strains with lumbar and caudal vertebral anomalies.
                                                                     Exp Anim. 2014;63(3):269-75.

                                                                                                                                                                                               

                                                                                                                                                                                                            Kochi T, Shimizu M, Shirakami Y, Yoshimi K, Kuramoto T, Tanaka T, Moriwaki H.
                                                                     Utility of Apc-mutant rats with a colitis-associated colon carcinogenesis model for chemoprevention studies.
                                                                     Eur J Cancer Prev. 2014 Sep 12. [Epub ahead of print]

                                                                                                                                                                                               

                                                                                                                                                                                                            Ohshima M, Taguchi A, Tsuda H, Sato Y, Yamahara K, Harada-Shiba M, Miyazato M,                                                                                                                                                                                                             Ikeda T, Iida H, Tsuji M
                                                                                                                                         Intraperitoneal and intravenous deliveries are not comparable in terms of drug                                                                     efficacy and cell distribution in neonatal mice with                                                                                                                                         hypoxia-ischemia.
                                                                     Brain Dev. 2014 Jul 14. pii: S0387-7604(14)00158-2.

                                                                                                                                                                                               

                                                                                                                                                                                                            Yoshimi K, Kaneko T, Voigt B, Mashimo T.
                                                                     Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform.
                                                                     Nat Commun. 2014 Jun 26;5:4240.

                                                                                                                                                                                               

                                                                                                                                                                                                            Tanaka T, Shimizu M, Kochi T, Shirakami Y, Mori T, Watanabe N, Naiki T, Moriwaki                                                                                                                                                                                                             H, Yoshimi K, Serikawa T, Kuramoto T.
                                                                     Apc-Mutant Kyoto Apc Delta (KAD) Rats Are Susceptible to 4-NQO-Induced Tongue Carcinogenesis.
                                                                     Cancers. 2014 Jul 21;6(3):1522-39.

                                                                                                                                                                                               

                                                                                                                                                                                                            Tanaka M, Izawa T, Yamate J, Franklin RJ, Kuramoto T, Serikawa T, Kuwamura M.
                                                                     The VF rat with abnormal myelinogenesis has a mutation in Dopey1.
                                                                     Glia. 2014 Sep;62(9):1530-42.                                                                                                                                                                                                    

                                                                                                                                                                                               

                                                                                                                                                                                                            Ferdaus MZ, Xiao B, Ohara H, Nemoto K, Harada Y, Saar K, Hübner N, Isomura M,                                                                                                                                         Nabika T
                                                                     Identification of stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
                                                                     PLoS One. 2014 Apr 15;9(4):e95091.

                                                                                                                                                                                               

                                                                                                                                                                                                            Yuya Harada, Yuki Nagao, Takahiro Mukai, Saki Shimizu, Kentaro Tokudome, Naofumi                                                                                                                                                                                                             Kunisawa, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno                                                                                                                                        
                                                                                                                                                                                                            Expressional Analysis of Inwardly Rectifying Kir4.1 Channels in Groggy Rats, a                                                                                                                                                                                                             Rat Model of Absence Seizures.
                                                                     Archives of Neuroscience. 2014 January; 2(1): e18651

                                                                                                                                                                                               

                                                                                                                                                                                                            Fumoto N, Mashimo T, Masui A, Ishida S, Mizuguchi Y, Minamimoto S, Ikeda A,                                                                                                                                         Takahashi R, Serikawa T, Ohno Y
                                                                     Evaluation of seizure foci and genes in the Lgi1(L385R/+) mutant rat.
                                                                     Neurosci Res. 2014 Mar;80:69-75.

                                                                                                                                                                                               

                                                                                                                                                                                                            Aivar P, Valero M, Bellistri E, Menendez de la Prida L.
                                                                     Extracellular Calcium Controls the Expression of Two Different Forms of Ripple-Like Hippocampal Oscillations.
                                                                     J Neurosci. 2014 Feb 19;34(8):2989-3004.

                                                                                                                                                                                               

                                                                                                                                                                                                            Sato A, Abe K, Yuzuriha M, Fujii S, Takahashi N, Hojo H, Teramoto S, Aoyama H.
                                                                     A novel mutation in the thyroglobulin gene that causes goiter and dwarfism in Wistar Hannover GALAS rats.
                                                                     Mutat Res Fundam Mol Mech Mutagen. 2014 Apr;762:17-23.

                                                                                                                                                                                               

                                                                                                                                                                                                            Tanaka Y, Nagao K, Nakagiri H, Nagaso T, Iwasa Y, Mori H, Asahina M, Imaizumi K,                                                                                                                                                                                                             Sato M.
                                                                                                                                         Unavailability of liver triacylglycerol increases serum cholesterol                                                                     concentration induced by dietary cholesterol in exogenously                                                                                                                                         hypercholesterolemic (ExHC) rats.
                                                                     Lipids Health Dis. 2014 Jan 22;13:19.

                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2013

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tada H, Kuroki Y, Funabashi T, Kamiya Y, Goto T, Suyama K, Sano A, Mitsushima D,                                                                                                                                                                                                                         Etgen AM, Takahashi T.
                                                                                                                                                 Phasic synaptic incorporation of GluR2-lacking AMPA receptors at                                                                         gonadotropin-releasing hormone neurons is involved in the generation of the                                                                                                                                                 luteinizing hormone surge in female rats.
                                                                         Neuroscience. 2013 Sep 17;248:664-66

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Aizawa-Abe M, Ebihara K, Ebihara C, Mashimo T, Takizawa A, Tomita T, Kusakabe T,                                                                                                                                                                                                                         Yamamoto Y, Aotani D, Yamamoto-Kataoka S, Sakai T, Hosoda K, Serikawa T, Nakao                                                                                                                                                                                                                         K.
                                                                         Generation of leptin-deficient Lepmkyo/Lepmkyo rats and identification of leptin-responsive genes in the liver.
                                                                         Physiol Genomics. 2013 Sep 3;45(17):786-793.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Y. Harada, Y. Nagao, S. Shimizu, T. Serikawa, R. Terada, M. Fujimoto, A. Okuda,                                                                                                                                                                                                                         T. Mukai, M. Sasa, Y. Kurachi, Y. Ohno.
                                                                         Expressional analysis of inwardly rectifying Kir4.1 channels in Noda epileptic rat (NER).
                                                                         Brain Res. 2013 Jun 23;1517:141-149.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Igarashi M, Hippo Y, Ochiai M, Fukuda H, Nakagama H.
                                                                                                                                                 AKT is critically involved in cooperation between obesity and the dietary                                                                         carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon                                                                                                                                                 carcinogenesis in rats.
                                                                         Biochem Biophys Res Commun. 2013 Dec 13. pii: S0006-291X(13)02128-1.[Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Sakuma T, Ochiai H, Kaneko T, Mashimo T, Tokumasu D, Sakane Y, Suzuki K,                                                                                                                                                 Miyamoto T, Sakamoto N, Matsuura S, Yamamoto T.
                                                                         Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity.
                                                                         Sci Rep. 2013 Nov 29;3:3379.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nigam R, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ.
                                                                         Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD.
                                                                         J Biomed Semantics. 2013 Nov 22;4(1):36.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Outani H, Okada M, Yamashita A, Nakagawa K, Yoshikawa H, Tsumaki N.
                                                                         Direct Induction of Chondrogenic Cells from Human Dermal Fibroblast Culture by Defined Factors.
                                                                         PLoS One. 2013 Oct 16;8(10):e77365.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Smith JR, Park CA, Nigam R, Laulederkind SJ, Hayman GT, Wang SJ, Lowry TF, Petri                                                                                                                                                                                                                         V, Pons JD, Tutaj M, Liu W, Worthey EA, Shimoyama M, Dwinell MR.
                                                                         The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications.
                                                                         J Biomed Semantics. 2013 Oct 8;4(1):26.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        D'Souza Z, McAdoo SP, Smith J, Pusey CD, Cook HT, Behmoaras J, Aitman TJ.
                                                                         Experimental crescentic glomerulonephritis: a new bicongenic rat model.
                                                                         Dis Model Mech. 2013 Nov-Dec;6(6):1477-86.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Matsuyama M, Haneda C, Kato K.
                                                                         Congenic strain differences of renal malformations in ACI/Mna rats by introgression of the chromosomal region of BUF/Mna rats containing Pur1.
                                                                         Nagoya J Med Sci. 2013 Aug;75(3-4):251-4.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Taketsuru H, Kaneko T.
                                                                         Efficient collection and cryopreservation of embryos in F344 strain inbred rats.
                                                                         Cryobiology. 2013 Aug 5. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yasuno K, Sakashita H, Kobayashi R, Araki S, Saito R, Shirota M, Kamiie J,                                                                                                                                                 Shitora K.
                                                                         Membranous Glomerulonephropathy in a Hatano Low-avoidance Rat.
                                                                         J Toxicol Pathol. 2013 Jun;26(2):203-8. Epub 2013 Jul 10.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Inoue S, Neoda Y, Yamasaki K, Hashimoto R, Mashimo T, Oda S,                                                                                                                                                 Serikawa T.
                                                                         Genetic and phenotypic characterization of a Japanese wild-derived DOB/Oda rat strain.
                                                                         Mamm Genome. 2013 Aug;24(7-8):303-8. Epub 2013 Jul 30.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Atanur SS, Diaz AG, Maratou K, Sarkis A, Rotival M, Game L, Tschannen MR,                                                                                                                                                 Kaisaki PJ, Otto GW, Ma MC, Keane TM, Hummel O, Saar K, Chen W, Guryev V,                                                                                                                                                 Gopalakrishnan K, Garrett MR, Joe B, Citterio L, Bianchi G, McBride M,                                                                                                                                                 Dominiczak A, Adams DJ, Serikawa T, Flicek P, Cuppen E, Hubner N, Petretto E,                                                                                                                                                 Gauguier D, Kwitek A, Jacob H, Aitman TJ.
                                                                         Genome Sequencing Reveals Loci under Artificial Selection that Underlie Disease Phenotypes in the Laboratory Rat.
                                                                         Cell. 2013 Aug 1;154(3):691-703. Epub 2013 Jul 25.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Aizawa-Abe M, Ebihara K, Ebihara C, Mashimo T, Takizawa A, Tomita T, Kusakabe T,                                                                                                                                                                                                                         Yamamoto Y, Aotani D, Yamamoto-Kataoka S, Sakai T, Hosoda K, Serikawa T, Nakao                                                                                                                                                                                                                         K.
                                                                         Generation of leptin deficient Lepmkyo/Lepmkyo rats and identification of leptin responsive genes in the liver.
                                                                         Physiol Genomics. 2013 Jun 25. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tomita Koichi, Nishibayashi Akimitsu, Yano Kenji, Hosokawa Ko.
                                                                         Differentiated Adipose-derived Stem Cells Promote Reinnervation of Rat Skin Flaps.
                                                                         Plast Reconstr Surg Glob Open                                                                                                                                                                                                                         2013;1:e22

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Gandolgor TA, Ohara H, Cui ZH, Hirashima T, Ogawa T, Saar K, Hübner N, Watanabe                                                                                                                                                                                                                         T, Isomura M, Nabika T.
                                                                                                                                                 Two genomic regions of chromosomes 1 and 18 explain most of the stroke                                                                         susceptibility under salt loading in stroke-prone spontaneously                                                                                                                                                 hypertensive rat/izm.
                                                                         Hypertension. 2013 Jul;62(1):55-61. doi: 10.1161/HYPERTENSIONAHA.111.00488. Epub 2013 May                                                                                                                                                 20.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Amelie Baud, Roel Hermsen, Victor Guryev, Pernilla Stridh, Delyth Graham, Martin                                                                                                                                                                                                                         W McBride, Tatiana Foroud, Sophie Calderari, Margarita Diez, Johan Ockinger,                                                                                                                                                 Amennai D Beyeen. Alan Gillett, Nada Abdelmagid, Andre Ortlieb Guerreiro-Cacais,                                                                                                                                                                                                                         Maja Jagodic, Jonatan Tuncel, Ulrika Norin, Elisabeth Beattie, Ngan Huynh,                                                                                                                                                 William H Miller, Daniel L Koller, Imranul Alam, Samreen Falak, Mary                                                                                                                                                 Osborne-Pellegrin, Esther Martinez-Membrives et al.
                                                                         Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.
                                                                         Nat Genet. 2013 May 26. doi: 10.1038/ng.2644. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Otsuka T, Kawaguchi Y.
                                                                         Common excitatory synaptic inputs to electrically connected cortical fast-spiking cell networks.
                                                                         J Neurophysiol. 2013 May 15. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yabushita S, Fukamachi K, Kikuchi F, Ozaki M, Miyata K, Sukata T, Deguchi Y,                                                                                                                                                 Tanaka H, Kakehashi A, Kawamura S, Uwagawa S, Wanibuchi H, Suzui M, Alexander                                                                                                                                                 DB, Tsuda H.
                                                                         Twenty-One Proteins Up-Regulated in Human H-ras Oncogene Transgenic Rat Pancreas Cancers are Up-Regulated in Human Pancreas Cancer.
                                                                         Pancreas. 2013 May 3. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Thelwall PE, Smith FE, Leavitt MC, Canty D, Hu W, Hollingsworth KG, Thoma C,                                                                                                                                                 Trenell MI, Taylor R, Rutkowski JV, Blamire AM, Quinn AG.
                                                                                                                                                 Hepatic Cholesteryl Ester Accumulation in Lysosomal Acid Lipase Deficiency:                                                                         Non-invasive Identification and Treatment Monitoring by Magnetic                                                                                                                                                 Resonance.
                                                                         J Hepatol. 2013 Apr 25. pii: S0168-8278(13)00270-5. doi: 10.1016/j.jhep.2013.04.016. [Epub                                                                                                                                                                                                                         ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Harada Y, Nagao Y, Shimizu S, Serikawa T, Terada R, Fujimoto M, Okuda A, Mukai                                                                                                                                                                                                                         T, Sasa M, Kurachi Y, Ohno Y.
                                                                         Expressional analysis of inwardly rectifying Kir4. 1 channels in Noda epileptic rat (NER).
                                                                         Brain Res. 2013 Apr 17. pii: S0006-8993(13)00522-2. doi: 10.1016/j.brainres.2013.04.009.                                                                                                                                                 [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Pandit S, Jeong JA, Jo JY, Cho HS, Kim DW, Kim JM, Ryu PD, Lee SY, Kim HW, Jeon                                                                                                                                                                                                                         BH, Park JB.
                                                                         Dual mechanisms diminishing tonic GABAA inhibition of dentate gyrus granule cells in Noda epileptic rats.
                                                                         J Neurophysiol. 2013 Apr 10. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Moriyama Y, Takagi N, Itokawa C, Tanonaka K.
                                                                         Injection of neural progenitor cells attenuates decrease in level of connexin 43 in brain capillaries after cerebral ischemia.
                                                                         Neurosci Lett. 2013 May 24;543:152-6. doi: 10.1016/j.neulet.2013.03.053. Epub 2013 Apr 9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ueta Y, Otsuka T, Morishima M, Ushimaru M, Kawaguchi Y.
                                                                         Multiple layer 5 pyramidal cell subtypes relay cortical feedback from secondary to primary motor areas in rats.
                                                                         Cereb Cortex. 2013 Apr 3. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Luo H, Higuchi K, Matsumoto K, Mori M.
                                                                         An interleukin-33 gene polymorphism is a modifier for eosinophilia in rats.
                                                                         Genes Immun. 2013 Apr;14(3):192-7. doi: 10.1038/gene.2013.7. Epub 2013 Feb 28.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Fukamachi K, Tanaka H, Sakai Y, Alexander DB, Futakuchi M, Tsuda H, Suzui M.
                                                                         A novel reporter rat strain that expresses LacZ upon Cre‐mediated recombination.
                                                                         Genesis. 2013 Apr;51(4):268-74. doi: 10.1002/dvg.22371. Epub 2013 Feb 25.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Kaneko T, Sakuma T, Kobayashi J, Kunihiro Y, Voigt B, Yamamoto                                                                                                                                                 T, Serikawa T.
                                                                         Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes.
                                                                         Sci Rep. 2013;3:1253. doi: 10.1038/srep01253. Epub 2013 Feb 13.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yoshimi K, Tanaka T, Serikawa T, Kuramoto T.
                                                                         Tumor Suppressor APC Protein Is Essential in Mucosal Repair from Colonic Inflammation through Angiogenesis.
                                                                         Am J Pathol. 2013 Apr;182(4):1263-74. doi: 10.1016/j.ajpath.2012.12.005. Epub 2013 Feb 8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hiraide S, Ueno K, Yamaguchi T, Matsumoto M, Yanagawa Y, Yoshioka M, Togashi H.
                                                                         Behavioural effects of monoamine reuptake inhibitors on symptomatic domains in an animal model of attention-deficit/hyperactivity disorder.
                                                                         Pharmacol Biochem Behav. 2013 Apr;105:89-97. doi: 10.1016/j.pbb.2013.01.009. Epub 2013 Feb                                                                                                                                                                                                                         1.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ohmori I, Hayashi K, Wang H, Ouchida M, Fujita N, Inoue T, Michiue H, Nishiki T,                                                                                                                                                                                                                         Matsui H.
                                                                         Inhalation of 10% carbon dioxide rapidly terminates Scn1a mutation-related hyperthermia-induced seizures.
                                                                         Epilepsy Res. 2013 Jan 30. pii: S0920-1211(13)00016-8. doi:                                                                                                                                                 10.1016/j.eplepsyres.2013.01.003. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2012

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yu B, Ueta H, Kitazawa Y, Tanaka T, Adachi K, Kimura H, Morita M, Sawanobori Y,                                                                                                                                                                                                                         Qian HX, Kodama T, Matsuno K.
                                                                         Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities.
                                                                         Hepatology. 2012 Oct;56(4):1532-1545.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Park CG, Rodriguez A, Ueta H, Lee H, Pack M, Matsuno K, Steinman RM.
                                                                         Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals.
                                                                         J Immunol Methods. 2012 Mar 30;377(1-2):15-22.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Koyama M, Yin C, Ishii H, Sakuma Y, Kato M.
                                                                         Somatostatin inhibition of GnRH neuronal activity and the morphological relationship between GnRH and somatostatin neurons in rats.
                                                                         Endocrinology. 2012 Feb;153(2):806-814.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kose H, Yamada T, Matsumoto K.
                                                                         Single Diabetic QTL Derived from OLETF Rat Is a Sufficient Agent for Severe Diabetic Phenotype in Combination with Leptin-Signaling Deficiency.
                                                                         Exp Diabetes Res. 2012;2012:858121.Epub 2012 Dec 5.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Watanabe K, Wada K, Ohashi T, Okubo S, Takekuma K, Hashizume R, Hayashi J,                                                                                                                                                 Serikawa T, Kuramoto T, Kikkawa Y.
                                                                         A 5-bp Insertion in Mip Causes Recessive Congenital Cataract in KFRS4/Kyo Rats.
                                                                         PLoS One, 2012, 7 (11), e50737.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nakabayashi A, Kamei N, Sunagawa T, Suzuki O, Ohkawa S, Kodama A, Kamei G, Ochi                                                                                                                                                                                                                         M.
                                                                         In vivo bioluminescence imaging of magnetically targeted bone marrow-derived mesenchymal stem cells in skeletal muscle injury model.
                                                                         J Orthop Res. 2012 Nov 28.[Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Blevins JE, Moralejo DH, Wolden-Hanson TH, Thatcher BS, Ho JM, Kaiyala KJ,                                                                                                                                                 Matsumoto K.
                                                                         Alterations in activity and energy expenditure contribute to lean phenotype in Fischer 344 rats lacking the cholecystokinin-1 receptor gene.
                                                                         Am J Physiol Regul Integr Comp Physiol. 2012 Dec;303(12):R1231-40. Epub 2012 Oct 31.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yamada T, Kose H, Ohta T, Matsumoto K.
                                                                         Genetic dissection of complex genetic factor involved in NIDDM of OLETF rat.
                                                                         Exp Diabetes Res. 2012;2012:582546. Epub 2012 Oct 15.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yoshimi K, Hashimoto T, Niwa Y, Hata K, Serikawa T, Tanaka T, Kuramoto T.
                                                                         Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay.
                                                                         BMC Cancer. 2012 Oct 3;12(1):448.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tanaka M, Soma K, Izawa T, Yamate J, Franklin RJ, Kuramoto T, Serikawa T,                                                                                                                                                 Kuwamura M.
                                                                         Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor.
                                                                         Brain Res. 2012 1488: 104-112.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yan HD, Ishihara K, Seki T, Hanaya R, Kurisu K, Arita K, Serikawa T, Sasa M.
                                                                                                                                                 Inhibitory effects of levetiracetam on the high-voltage-activated L-type Ca(2+)                                                                         channels in hippocampal CA3 neurons of spontaneously epileptic rat                                                                                                                                                 (SER).
                                                                         Brain Res Bull. 2013 Jan;90:142-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Takizawa A, Kobayashi J, Kunihiro Y, Yoshimi K, Ishida S, Tanabe K,                                                                                                                                                                                                                         Yanagi A, Tachibana A, Hirose J, Yomoda J, Morimoto S, Kuramoto T, Voigt B,                                                                                                                                                 Watanabe T, Hiai H, Tateno C, Komatsu K, Serikawa T.
                                                                         Generation and characterization of severe combined immunodeficiency rats.
                                                                         Cell Rep. 2012 Sep 27;2(3):685-94.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kodama A, Kamei N, Kamei G, Kongcharoensombat W, Ohkawa S, Nakabayashi A, Ochi                                                                                                                                                                                                                         M.
                                                                         In vivo bioluminescence imaging of transplanted bone marrow mesenchymal stromal cells using a magnetic delivery system in a rat fracture model.
                                                                         J Bone Joint Surg Br. 2012 Jul;94(7):998-1006.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Nakanishi S, Ochiai M, Nakagama H, Voigt B, Serikawa T.
                                                                         Origins of Albino and Hooded Rats: Implications from Molecular Genetic Analysis across Modern Laboratory Rat Strains.
                                                                         PLoS One. 2012;7(8):e43059.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hernández Vera R, Vilahur G, Ferrer-Lorente R, Peña E, Badimon L.
                                                                                                                                                 Platelets derived from the bone marrow of diabetic animals show dysregulated                                                                         endoplasmic reticulum stress proteins that contribute to increased                                                                                                                                                 thrombosis.
                                                                         Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2141-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yao H, Nabika T.
                                                                         Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: With a systematic review of recent articles.
                                                                         J Transl Med. 2012 Jul 6;10(1):139. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Quina L, Kuramoto T, Luquetti DV, Cox TC, Serikawa T, Turner EE.
                                                                                                                                                 Deletion of a conserved regulatory element required for Hmx1 expression in                                                                         craniofacial mesenchyme in the dumbo rat: a novel cause of congenital                                                                                                                                                 ear malformation.
                                                                         Dis Model Mech. 2012 Jun 26. [Epub ahead of print]                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hata T, Uemoto S, Fujimoto Y, Murakami T, Tateno C, Yoshizato K, Kobayashi E.
                                                                         Transplantation of Engineered Chimeric Liver With Autologous Hepatocytes and Xenobiotic Scaffold.
                                                                         Ann Surg. 2012 Jun 11. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nakano T, Lai CY, Goto S, Hsu LW, Kawamoto S, Ono K, Chen KD, Lin CC, Chiu KW,                                                                                                                                                                                                                         Wang CC, Cheng YF, Chen CL.
                                                                         Immunological and regenerative aspects of hepatic mast cells in liver allograft rejection and tolerance.
                                                                         PLoS One. 2012;7(5):e37202.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Baulac S, Ishida S, Mashimo T, Boillot M, Fumoto N, Kuwamura M, Ohno Y, Takizawa                                                                                                                                                                                                                         A, Aoto T, Ueda M, Ikeda A, Leguern E, Takahashi R, Serikawa T.
                                                                         A RAT MODEL FOR LGI1-RELATED EPILEPSIES.
                                                                         Hum Mol Genet. 2012 May 15. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kaneko T, Serikawa T                                                                                                                                                
                                                                                                                                                                                                                        Successful Long-Term Preservation of Rat Sperm by Freeze-Drying.                                                                                                                                                
                                                                                                                                                                                                                        PLoS ONE. 2012 7(4):                                                                                                                                                 e35043.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Moriya T, Kitamori K, Naito H, Yanagiba Y, Ito Y, Yamagishi N, Tamada H, Jia X,                                                                                                                                                                                                                         Tsuchikura S, Ikeda K, Yamori Y, Nakajima T.                                                                                                                                                
                                                                                                                                                                                                                        Simultaneous changes in high-fat and high-cholesterol diet-induced                                                                                                                                                 steatohepatitis and severe fibrosis and those underlying molecular mechanisms in                                                                                                                                                                                                                         novel SHRSP5/Dmcr rat.
                                                                         Environ Health Prev Med. 2012 Nov;17(6):444-56.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Takano M, Katsumata Y, Ogawa J, Ebata T, Urasoko Y, Asano Y, Serikawa T,                                                                                                                                                 Kuramoto T.
                                                                         Morphological features of mutant rat, IS-Tlk/Kyo, fetuses with caudal vertebral anomalies.                                                                                                                                                
                                                                                                                                                                                                                        Congenit Anom (Kyoto).                                                                                                                                                 52(1):42-47, 2012                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Asahina M, Mashimo T, Takeyama M, Tozawa R, Hashimoto T, Takizawa A, Ueda M,                                                                                                                                                 Aoto T, Kuramoto T, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Hypercholesterolemia and atherosclerosis in low density lipoprotein receptor                                                                                                                                                 mutant rats.                                                                                                                                                
                                                                                                                                                                                                                        Biochem Biophys Res                                                                                                                                                 Commun. 418(3):553-8, 2012                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2011

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Liang-Cai Zhao, Xiao-Dong Zhang, Heyo Wang, and Donghai Lin.
                                                                         1H NMR-BASED METABONOMIC ANALYSIS OF METABOLIC CHANGES OF SERUM AND LIVER IN ZUCKER OBESE RATS.
                                                                         Taylor & Francis Analytical Letters, 2011, 44, 1579-1590

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Page TH, D'Souza Z, Nakanishi S, Serikawa T, Pusey CD, Aitman TJ, Cook HT,                                                                                                                                                 Behmoaras J.
                                                                         Role of a novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis.
                                                                         J Biol Chem. 2011 Dec 19. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ishida S, Sakamoto Y, Nishio T, Baulac S, Kuwamura M, Ohno Y, Takizawa A, Kaneko                                                                                                                                                                                                                         S, Serikawa T, Mashimo T.
                                                                         Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
                                                                         Brain Res. 2011 Nov 13. [Epub ahead of print]

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Yokoe M, Hashimoto R, Hiai H, Serikawa T.
                                                                         A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene.
                                                                         BMC Genetics 12:91, 2011

                                                                                                                                                                                                           

                                                                                                                                                                                                                        McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P,                                                                                                                                                                                                                         Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D,                                                                                                                                                                                                                         Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F,                                                                                                                                                 Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton                                                                                                                                                                                                                         PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA.
                                                                         Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
                                                                         Nature. 2011 Oct 5;478(7367):114-8

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K,                                                                                                                                                 Tsuchikura S, Yasui N, Ikeda K, Moriya T, Yamori Y, Nakajima T.
                                                                         Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr.
                                                                         Environ Health Prev Med. Epub 2011 Aug 19.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Y Moriyama, N Takagi and K Tanonaka
                                                                         Intravenous injection of neural progenitor cells improved depression-like behavior after cerebral ischemia
                                                                         Translational Psychiatry (2011) 1, e29

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Fukumura T, Kose H, Takeda C, Kurita Y, Ochiai K, Yamada T, Matsumoto K.
                                                                         Genetic interaction between hyperglycemic QTLs is manifested under a high calorie diet in OLETF-derived congenic rats.
                                                                         Exp Anim. 2011;60(2):125-32.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hayashi K, Ueshima S, Ouchida M, Mashimo T, Nishiki T, Sendo T, Serikawa T,                                                                                                                                                 Matsui H, Ohmori I.
                                                                         Therapy for hyperthermia-induced seizures in Scn1a mutant rats.
                                                                         Epilepsia 52(5):1010-1017, 2011

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuwamura M, Inumaki K, Tanaka M, Shirai M, Izawa T, Yamate J, Franklin RJ,                                                                                                                                                 Kuramoto T, Serikawa T.
                                                                         Oligodendroglial pathology in the development of myelin breakdown in the dmy mutant rat.
                                                                         Brain Res. 2011 May 10;1389:161-8. Epub 2011 Mar 9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Kuwamura M, Tokuda S, Izawa T, Nakane Y, Kitada K, Akao M, Guénet                                                                                                                                                 JL, Serikawa T.
                                                                         A mutation in the gene encoding mitochondrial Mg²+ channel MRS2 results in demyelination in the rat.                                                                                                                                                
                                                                                                                                                                                                                        PLoS Genet. 2011 Jan                                                                                                                                                 6;7(1):e1001262.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Kuwamura M, Tagami F, Mashimo T, Nose M, Serikawa T.
                                                                         Kyoto rhino rats derived by ENU mutagenesis undergo congenital hair loss and exhibit focal glomerulosclerosis.
                                                                         Exp Anim. 2011;60(1):57-63.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Xiao B, Harada Y, Kawakami K, Nabika T.
                                                                                                                                                 A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress:                                                                         evaluation in reciprocal congenic strains between stroke-prone                                                                                                                                                 spontaneously hypertensive rat and Wistar-Kyoto rat.
                                                                         J Hypertens. 2011 Feb;29(2):257-65.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Torigoe D, Ichii O, Dang R, Ohnaka T, Okano S, Sasaki N, Kon Y, Agui T.
                                                                         High-resolution linkage mapping of the rat hooded locus.
                                                                         J Vet Med Sci. 2011 May;73(5):707-10. Epub 2011 Jan 6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tanaka H, Arimura Y, Yabana T, Goto A, Hosokawa M, Nagaishi K, Yamashita K,                                                                                                                                                 Yamamoto H, Sasaki Y, Fujimiya M, Imai K, Shinomura Y.
                                                                         Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat.
                                                                         J Gastroenterol. 2011 Feb;46(2):143-52.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2010

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Arun P, Madhavarao CN, Moffett JR, Hamilton K, Grunberg NE, Ariyannur PS, Gahl                                                                                                                                                                                                                         WA, Anikster Y, Mog S, Hallows WC, Denu JM, Namboodiri AM.
                                                                         Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease.
                                                                         J Inherit Metab Dis. 2010 Jun;33(3):195-210.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tanaka N., Ishii H., Yin C., Koyama M., Sakuma Y., Kato M.
                                                                         Voltage-gated Ca2+ channel mRNAs and T-type Ca2+ currents in rat gonadotropin-releasing hormone neurons.
                                                                         J. Physiol. Sci. 2010 May;60(3):195-204.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Matsuno K, Ueta H, Shu Z, Xue-Dong X, Sawanobori Y, Kitazawa Y, Bin Y, Yamashita                                                                                                                                                                                                                         M, Shi C.
                                                                         The microstructure of secondary lymphoid organs that support immune cell trafficking.
                                                                         Arch Histol Cytol. 2010;73(1):1-21. Review.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ishikane S, Yamahara K, Sada M, Harada K, Kodama M, Ishibashi-Ueda H, Hayakawa                                                                                                                                                                                                                         K, Mishima K, Iwasaki K, Fujiwara M, Kangawa K, Ikeda T.
                                                                         Allogeneic administration of fetal membrane-derived mesenchymal stem cells attenuates acute myocarditis in rats.
                                                                         J Mol Cell Cardiol. 2010 Nov;49(5):753-61.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tsuda H, Yamahara K, Ishikane S, Otani K, Nakamura A, Sawai K, Ichimaru N, Sada                                                                                                                                                                                                                         M, Taguchi A, Hosoda H, Tsuji M, Kawachi H, Horio M, Isaka Y, Kangawa K,                                                                                                                                                 Takahara S, Ikeda T.
                                                                         Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis.
                                                                         Am J Physiol Renal Physiol. 2010 Nov;299(5):F1004-13.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Zhao LC, Zhang XD, Liao SX, Gao HC, Wang HY, Lin DH.
                                                                         A metabonomic comparison of urinary changes in Zucker and GK rats.
                                                                         J Biomed Biotechnol. 2010;2010:431894.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Sakurai-Yamashita Y, Nabika T, Niwa M.
                                                                         Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats.
                                                                         Cell Mol Neurobiol. 2010 Mar;30(2):283-7.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ishimaru Y, Chiba S, Serikawa T, Sasa M, Inaba H, Tamura Y, Ishimoto T, Takasaki                                                                                                                                                                                                                         H, Sakamoto K, Yamaguchi K.
                                                                         Effects of levetiracetam on hippocampal kindling in Noda epileptic rats.
                                                                         Brain Res. 2010 Jan 14;1309:104-9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kashiwazaki N, Seita Y, Takizawa A, Maedomari N, Ito J, Serikawa T.
                                                                         Techniques for in vitro and in vivo fertilization in the rat.
                                                                         Methods Mol Biol. 2010;597:311-22.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Ohmori I, Ouchida M, Ohno Y, Tsurumi T, Miki T, Wakamori M, Ishihara                                                                                                                                                                                                                         S, Yoshida T, Takizawa A, Kato M, Hirabayashi M, Sasa M, Mori Y, Serikawa T.
                                                                         A missense mutation of the gene encoding voltage-dependent sodium channel (Nav1.1) confers susceptibility to febrile seizures in rats.
                                                                         J Neurosci. 2010 Apr 21;30(16):5744-53.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Nakanishi S, Yamasaki K, Kumafuji K, Sakakibara Y, Neoda Y, Takizawa                                                                                                                                                                                                                         A, Kaneko T, Otsuki M, Hashimoto R, Voigt V, Mashimo T, Serikawa T.
                                                                         Genetic Quality Control of the Rat Strains at the National Bio Resource Project – Rat.                                                                                                                                                
                                                                                                                                                                                                                        IBC 2010, vol. 2,                                                                                                                                                 article no. 12. doi: 10.4051/ibc.2010.2.4.0012                                                                                                                                        

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ohno Y, Ishihara S, Mashimo T, Sofue N, Shimizu S, Imaoku T, Tsurumi T, Sasa M,                                                                                                                                                                                                                         Serikawa T.
                                                                         Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures.
                                                                         Neurobiol Dis. 2010 Sep 25. [Epub ahead of print]                                                                                                                                        

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tokuda S, Sofue N, Ohno Y, Sasa M, Serikawa T.
                                                                         Inhibitory effects of levetiracetam on absence seizures in a novel absence-like epilepsy animal model, Groggy rat.
                                                                         Brain Res. 2010 Nov 4;1359:298-303.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ohno Y, Sofue N, Imaoku T, Morishita E, Kumafuji K, Sasa M, Serikawa T.
                                                                         Serotonergic modulation of absence-like seizures in groggy rats: a novel rat model of absence epilepsy.
                                                                         J Pharmacol Sci. 2010 Sep 16;114(1):99-105.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Izawa T, Yamate J, Franklin RJ, Kuwamura M.
                                                                         Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat.
                                                                         Brain Res. 2010 Aug 19;1349:105-14.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ohno Y, Sofue N, Ishihara S, Mashimo T, Sasa M, Serikawa T.
                                                                         Scn1a missense mutation impairs GABA(A) receptor-mediated synaptic transmission in the rat hippocampus.
                                                                         Biochem Biophys Res Commun. 2010 Sep 10;400(1):117-22.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hata T, Iwasaki J, Hishikawa S, Fujimoto Y, Uemoto S, Kobayashi E.
                                                                         Development of a portocaval shunt using a small intestinal segment in rats.
                                                                         Microsurgery. 2010 May;30(4):302-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Iwasaki J, Hata T, Hishikawa S, Fujimoto Y, Uemoto S, Murakami T, Kobayashi E.
                                                                         Use of rat segmental intestine for fetal pancreatic transplantation.
                                                                         Microsurgery. 2010 May;30(4):296-301.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Hirano R, Kuwamura M, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Identification of the Rat Rex Mutation as a 7-Bp Deletion at Splicing Acceptor                                                                                                                                                                                                                         Site of the Krt71 Gene.
                                                                         J Vet Med Sci. 2010 Jul;72(7):909-12.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Generation of knockout rats with X-linked severe combined immunodeficiency                                                                                                                                                 (X-SCID) using zinc-finger nucleases.
                                                                         PLoS One. 2010 Jan 25;5(1):e8870.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Yokoe M, Yagasaki K, Kawaguchi T, Kumafuji K, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Genetic analyses of fancy rat-derived mutations.
                                                                         Exp Anim. 2010;59(2):147-55.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Izawa T, Yamate J, Franklin RJ, Kuwamura M.
                                                                         Abnormal myelinogenesis both in the white and gray matter of the attractin-deficient mv rat.
                                                                         Brain Res. 2010 Feb 2;1312:145-55.                                                                                                                                        

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yamazaki Y, Akashi R, Banno Y, Endo T, Ezura H, Fukami-Kobayashi K, Inaba K, Isa                                                                                                                                                                                                                         T, Kamei K, Kasai F, Kobayashi M, Kurata N, Kusaba M, Matuzawa T, Mitani S,                                                                                                                                                 Nakamura T, Nakamura Y, Nakatsuji N, Naruse K, Niki H, Nitasaka E, Obata Y,                                                                                                                                                 Okamoto H, Okuma M, Sato K, Serikawa T, Shiroishi T, Sugawara H, Urushibara H,                                                                                                                                                                                                                         Yamamoto M, Yaoita Y, Yoshiki A, Kohara Y.                                                                                                                                                
                                                                                                                                                                                                                        NBRP databases: databases of biological resources in Japan.
                                                                         Nucleic Acids Res. 2010 Jan;38(Database issue):D26-32.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2009

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Watanabe M., Sakuma Y., Kato M.
                                                                         GABAA receptors mediated excitation in adult rat GnRH neurons.
                                                                         Biol Reprod. 2009 Aug;81(2):327-332.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kato M., Tanaka N., Ishii H., Yin C., Sakuma Y.
                                                                         Ca2+ channels and Ca2+-activated K+ channels in adult rat gonadotrophin-releasing hormone neurones.
                                                                         J Neuroendocrinol. 2009 Mar;21(4):312-315.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ohno Y, Shimizu S, Harada Y, Morishita M, Ishihara S, Kumafuji K, Sasa M,                                                                                                                                                 Serikawa T.
                                                                         Regional expression of Fos-like immunoreactivity following seizures in Noda epileptic rat (NER).
                                                                         Epilepsy Res. 2009 Nov;87(1):70-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Voigt B, Serikawa T.
                                                                         Pluripotent stem cells and other technologies will eventually open the door for straightforward gene targeting in the rat.
                                                                         Dis Model Mech. 2009 Jul-Aug;2(7-8):341-3.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mori M, Fu X, Chen L, Zhang G, Higuchi K.
                                                                         Hereditary pancreatitis model WBN/Kob rat strain has a unique haplotype in the Pdwk1 region on chromosome 7.
                                                                         Exp Anim. 2009 Jul;58(4):409-13.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yoshimi K, Tanaka T, Takizawa A, Kato M, Hirabayashi M, Mashimo T, Serikawa T,                                                                                                                                                                                                                         Kuramoto T.
                                                                         Enhanced colitis-associated colon carcinogenesis in a novel Apc mutant rat.
                                                                         Cancer Sci. 2009 Nov;100(11):2022-7.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Serikawa T, Mashimo T, Takizawa A, Okajima R, Maedomari N, Kumafuji K, Tagami F,                                                                                                                                                                                                                         Neoda Y, Otsuki M, Nakanishi S, Yamasaki K, Voigt B, Kuramoto T.                                                                                                                                                
                                                                                                                                                                                                                        National BioResource Project-Rat and related activities.
                                                                         Exp Anim. 2009 Jul;58(4):333-41.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Arao Y, Hakamata Y, Igarashi Y, Sato Y, Kayama F, Takahashi M, Kobayashi E,                                                                                                                                                 Murakami T.
                                                                         Characterization of hepatic sexual dimorphism in Alb-DsRed2 transgenic rats.
                                                                         Biochem Biophys Res Commun. 2009 Apr 24;382(1):46-50.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kose H, Sado Y, Yamada T, Matsumoto K.
                                                                         Genetic mapping found major QTLs for antibody-induced glomerulonephritis in WKY rats.
                                                                         Exp Anim. 2009 Apr;58(2):193-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Takagi Y, Kuramoto T, Voigt B, Tsurumi T, Nakanishi S, Mashimo T, Masui N,                                                                                                                                                 Serikawa T.
                                                                         An informative set of SSLP markers and genomic profiles in the rat MHC, the RT1 complex.
                                                                         Immunogenetics. 2009 Mar;61(3):189-97.
                                                                         Erratum of Fig.1.
                                                                         Immunogenetics.                                                                                                                                                                                                                         2009 Apr 2.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Serikawa T.
                                                                         Rat resources in biomedical research.
                                                                         Curr Pharm Biotechnol. 2009 Feb;10(2):214-20.                                                                                                                                        

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hirabayashi M, Yoshizawa Y, Kato M, Tsuchiya T, Nagao S, Hochi S.
                                                                         Availability of subfertile transgenic rats expressing the c-myc gene as recipients for spermatogonial transplantation.
                                                                         Transgenic Res. 2009 Feb;18(1):135-41.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Iigaya K, Kumagai H, Nabika T, Harada Y, Onimaru H, Oshima N, Takimoto C,                                                                                                                                                 Kamayachi T, Saruta T, Itoh H.
                                                                         Relation of blood pressure quantitative trait locus on rat chromosome 1 to hyperactivity of rostral ventrolateral medulla.
                                                                         Hypertension. 2009 Jan;53(1):42-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Wang J, Leone P, Wu G, Francis JS, Li H, Jain MR, Serikawa T, Ledeen RW.
                                                                         Myelin Lipid Abnormalities in the Aspartoacylase-Deficient Tremor Rat.
                                                                         Neurochem Res. 2009 Jan;34(1):138-48.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Naoi K, Kuramoto T, Kuwamura Y, Gohma H, Kuwamura M, Serikawa T.
                                                                         Characterization of the Kyoto circling (KCI) rat carrying a spontaneous nonsense mutation in the protocadherin 15 (Pcdh15) gene.
                                                                         Exp Anim. 2009 Jan;58(1):1-10.

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2008

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tsuchida A, Yokoi N, Namae M, Fuse M, Masuyama T, Sasaki M, Kawazu S, Komeda K.
                                                                         Phenotypic characterization of the Komeda miniature rat Ishikawa, an animal model of dwarfism caused by a mutation in Prkg2.
                                                                         Comp Med. 2008 Dec;58(6):560-7.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ishikane S, Ohnishi S, Yamahara K, Sada M, Harada K, Mishima K, Iwasaki K,                                                                                                                                                 Fujiwara M, Kitamura S, Nagaya N, Ikeda T.                                                                                                                                                
                                                                                                                                                                                                                        Allogeneic injection of fetal membrane-derived mesenchymal stem cells induces                                                                                                                                                 therapeutic angiogenesis in a rat model of hind limb ischemia.
                                                                         Stem Cells. 2008 Oct;26(10):2625-33.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ishikawa N, Harada Y, Maruyama R, Masuda J, Nabika T.                                                                                                                                                
                                                                                                                                                                                                                        Genetic effects of blood pressure quantitative trait loci on                                                                                                                                                 hypertension-related organ damage: evaluation using multiple congenic strains.
                                                                         Hypertens Res. 2008 Sep;31(9):1773-9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuwamura M, Okajima R, Yamate J, Kotani T, Kuramoto T, Serikawa T.
                                                                         Pancreatic Metaplasia in the Gastro-achlorhydria in WTC-dfk Rat, a Potassium Channel Kcnq1 Mutant.
                                                                         Vet Pathol. 2008 Jul;45(4):586-91.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nature Genetics EDITORIAL
                                                                         Year of the Rat
                                                                         Nat Genet. 2008 May;40(5):513.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Yanagihara K, Tokuda S, Voigt B, Takizawa A, Nakajima R, Kato M,                                                                                                                                                 Hirabayashi M, Kuramoto T, Serikawa T.
                                                                         An ENU-induced mutant archive for gene targeting in rats.
                                                                         Nat Genet. 2008 May;40(5):514-5.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J,                                                                                                                                                 Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob                                                                                                                                                                                                                         HJ, Kuramoto T, Kwitek AE, Marrone A, Mashimo T, Moreno C, Mullins J, Mullins L,                                                                                                                                                                                                                         Olsson T, Pravenec M, Riley L, Saar K, Serikawa T, Shull JD, Szpirer C, Twigger                                                                                                                                                                                                                         SN, Voigt B, Worley K.                                                                                                                                                
                                                                                                                                                                                                                        Progress and prospects in rat genetics: a community view.
                                                                         Nat Genet. 2008 May;40(5):516-22.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Behmoaras J, Bhangal G, Smith J, McDonald K, Mutch B, Lai PC, Domin J, Game L,                                                                                                                                                                                                                         Salama A, Foxwell BM, Pusey CD, Cook HT, Aitman TJ.                                                                                                                                                
                                                                                                                                                                                                                        Jund is a determinant of macrophage activation and is associated with                                                                                                                                                 glomerulonephritis susceptibility.
                                                                         Nat Genet. 2008 May;40(5):553-9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        STAR Consortium, Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y,                                                                                                                                                                                                                         Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier                                                                                                                                                                                                                         D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl                                                                                                                                                                                                                         H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo                                                                                                                                                                                                                         T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M,                                                                                                                                                 Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M,                                                                                                                                                 Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N.
                                                                         SNP and haplotype mapping for genetic analysis in the rat.
                                                                         Nat Genet. 2008 May;40(5):560-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mochizuki N, Takagi N, Kurokawa K, Onozato C, Moriyama Y, Tanonaka K, Takeo S.
                                                                         Injection of neural progenitor cells improved learning and memory dysfunction after cerebral ischemia.
                                                                         Exp Neurol. 2008 May;211(1):194-202.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nakano T, Goto S, Lai CY, Hsu LW, Wong JL, Kawamoto S, Chiang KC, Ohmori N, Goto                                                                                                                                                                                                                         T, Sato S, Yang CH, Wang CC, Jawan B, Cheng YF, Ono K, Chen CL.                                                                                                                                                
                                                                                                                                                                                                                        Involvement of autoimmunity against nuclear histone H1 in liver transplantation                                                                                                                                                                                                                         tolerance.
                                                                         Transpl Immunol. 2008 May;19(2):87-92.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Seki T, Shimokawa N, Iizuka H, Takagishi K, Koibuchi N.
                                                                         Abnormalities of vertebral formation and Hox expression in congenital kyphoscoliotic rats.
                                                                         Mol Cell Biochem. 2008 May;312(1-2):193-9.                                                                                                                                                                                                                

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kose H, Yamada T, Matsumoto K.                                                                                                                                                
                                                                                                                                                                                                                        OLETF allele of hyperglycemic QTL Nidd3/of is dominant.
                                                                         Exp Anim. 2008 Apr;57(2):135-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Nakanishi S, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Functional polymorphisms in inbred rat strains and their allele frequencies in                                                                                                                                                                                                                         commercially available outbred stocks.
                                                                         Physiol Genomics. 2008 Apr 22;33(2):205-11.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Ueta H, Shi C, Miyanari N, Xu XD, Zhou S, Yamashita M, Ezaki T, Matsuno K.                                                                                                                                                
                                                                                                                                                                                                                        Systemic transmigration of allosensitizing donor dendritic cells to host                                                                                                                                                 secondary lymphoid organs after rat liver transplantation.
                                                                         Hepatology. 2008 Apr;47(4):1352-62.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hanaya R, Kiura Y, Kurisu K, Sakai N, Serikawa T, Sasa M                                                                                                                                                
                                                                                                                                                                                                                        N-acetyl-L-aspartate activates hippocampal CA3 neurons in rodent slice                                                                                                                                                 preparations.
                                                                         Brain Res Bull. 2008 Mar 28;75(5):663-7.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mochizuki N, Takagi N, Onozato C, Moriyama Y, Takeo S, Tanonaka K.                                                                                                                                                
                                                                                                                                                                                                                        Delayed injection of neural progenitor cells improved spatial learning                                                                                                                                                 dysfunction after cerebral ischemia.
                                                                         Biochem Biophys Res Commun 2008 Mar 28;368(1):151-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Wang T, Nabika T, Notsu Y, Takabatake T.
                                                                         Sympathetic regulation of the renal functions in rats reciprocally congenic for chromosome 1 blood pressure quantitative trait locus.
                                                                         Hypertens Res. 2008 Mar;31(3):561-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Voigt B, Kuramoto T, Mashimo T, Tsurumi T, Sasaki Y, Hokao R, Serikawa T.                                                                                                                                                
                                                                                                                                                                                                                        Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic                                                                                                                                                 dissection of complex traits.
                                                                         Physiol Genomics 2008 Feb 19;32(3):335-42.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2007

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H.
                                                                         Rat wct mutation induces a hypo-mineralization form of amelogenesis imperfecta and cyst formation in molar teeth.
                                                                         Cell Tissue Res. 2007 Oct;330(1):97-109.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tanaka K, Shirakawa H, Okada K, Konno K, Nakagawa T, Serikawa T, Kaneko S.
                                                                         Increased Ca2+ channel currents in cerebellar Purkinje cells of the ataxic groggy rat.
                                                                         Neurosci Lett. 2007 Oct 16;426(2):75-80.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H.
                                                                         Rat wct mutation prevents differentiation of maturation-stage ameloblasts resulting in hypo-mineralization in incisor teeth.
                                                                         Histochem Cell Biol 2007 Sep;128(3):183-93.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kose H, Bando Y, Izumi K, Yamada T, Matsumoto K.
                                                                         Epistasis between hyperglycemic QTLs revealed in a double congenic of the OLETF rat.
                                                                         Mamm Genome. 2007 Aug;18(8):609-15.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Shono S, Kose H, Yamada T, Matsumoto K.
                                                                         Proteomic analysis of a diabetic congenic rat identified age-dependent alteration of an acidic protein.
                                                                         J Med Invest. 2007 Aug;54(3-4):289-94.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kose H, Sakai T, Tsukumo S, Wei K, Yamada T, Yasutomo K, Matsumoto K.
                                                                         Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase kappa gene in LEC rats.
                                                                         Genomics. 2007 Jun;89(6):673-7.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mori M, Sawashita J, Higuchi K.
                                                                         Functional Polymorphisms of the Lss and Fdft1 Genes in Laboratory Rats.
                                                                         Exp Anim. 2007 Apr;56(2):93-101.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nakano T, Goto S, Lai CY, Hsu LW, Kao YH, Lin YC, Kawamoto S, Chiang KC, Ohmori                                                                                                                                                                                                                         N, Goto T, Sato S, Jawan B, Cheng YF, Ono K, Chen CL.
                                                                         Experimental and clinical significance of anti-nuclear antibodies in liver transplantation.
                                                                         Transplantation. 2007 Apr 27;83(8):1122-5.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yan H-D, Ishihara K, Hanaya R, Kurisu K, Serikawa T, Sasa M.
                                                                         Voltage-dependent calcium channel abnormalities in hippocampal CA3 neurons of spontaneously epileptic rats.
                                                                         Epilepsia. 2007 Apr;48(4):758-64.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Nakano T, Chen CL, Goto S, Lai CY, Hsu LW, Kawamoto S, Sasaki T, Lin YC, Kao YH,                                                                                                                                                                                                                         Ohmori N, Goto T, Sato S, Jawan B, Ono K, Cheng YF.
                                                                         The immunological role of lipid transfer/metabolic proteins in liver transplantation tolerance.
                                                                         Transplant Immunol. 2007 Feb;17(2):130-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tokuda S, Kuramoto T, Tanaka T, Kaneko S, Takeuchi IK, Sasa M, and Serikawa T.
                                                                         The ataxic groggy rat has a missense mutation in the P/Q-type voltage gated Ca2+ channel alpha1A subunit gene and exhibits absence seizures.
                                                                         Brain Res. 2007 Feb 16;1133(1):168-77.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kashiwazaki N, Seita Y, Naoi K, Takizawa A, Kuramoto T, and Serikawa T.
                                                                         Generation of rat offspring derived from cryopreserved spermatozoa in Japanese National Bioresources.
                                                                         Reprod Fertil Dev. 19(1):124-125, 2007.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2006

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Shinohara T, Kato M, Takehashi M, Lee J, Chuma S, Nakatsuji N, Kanatsu-Shinohara                                                                                                                                                                                                                         M, Hirabayashi M.
                                                                         Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination.
                                                                         Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13624-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Voigt B, Tsurumi T, Naoi K, Nakanishi S, Yamasaki K, Kuramoto T, and                                                                                                                                                                                                                         Serikawa T.
                                                                         A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains.
                                                                         BMC Genetics. 2006 Apr 4;7:19.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tachibana M, Lu LM, Hiai H, Tamura A, Matsushima Y, Shisa H.
                                                                                                                                                 Quantitative trait loci determining weight reduction of testes and pituitary by                                                                         diethylstilbesterol in LEXF and FXLE recombinant inbred strain                                                                                                                                                 rats.
                                                                         Exp Anim. 2006 Apr;55(2):91-5.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J,                                                                                                                                                 Roberton-Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG,                                                                                                                                                 Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey                                                                                                                                                                                                                         CD, Cook HT.
                                                                         Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans.
                                                                         Nature. 2006 Feb 16;439(7078):851-5.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Gohma H, Kuramoto T, Kuwamura M, Okajima R, Tanimoto N, Yamasaki K, Nakanishi S,                                                                                                                                                                                                                         Kitada K, Makiyama T, Akao M, Kita T, Sasa M, Serikawa T.
                                                                         WTC deafness Kyoto (dfk): a rat model for extensive investigations of Kcnq1 functions.
                                                                         Physiol Genomics. 2006 Feb 14;24(3):198-206.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Hiai H, Liu H, Omi N, Tanuma J, Higashi K.
                                                                         DRH strain rats: Genetic resistance to chemical hepatocarcinogenesis.
                                                                         Trends in Cancer Research. 2: 127-134, 2006.                                                                                                                                        

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2005

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Klugmann M1, Leichtlein CB, Symes CW, Serikawa T, Young D, During MJ.
                                                                         Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.
                                                                         Mol Ther. 2005 May;11(5):745-53.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Choose Your Rat.
                                                                         Science. 309:361, 2005.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Masuyama T, Miyajima K, Ohshima H, Osawa M, Yokoi N, Oikawa T, Taniguchi K.
                                                                                                                                                 A novel autosomal recessive mutation whitish chalk-like teeth (wct) resembling                                                                         amelogenesis imperfecta maps to rat chromosome 14 corresponding to                                                                                                                                                 human 4q21.
                                                                         Eur J Oral Sci. 2005 Dec;113(6):451-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Yamashita S, Wakazono K, Nomoto T, Tsujino Y, Kuramoto T, Ushijima T.
                                                                         Expression quantitative trait loci analysis of 13 genes in the rat prostate.
                                                                         Genetics. 2005 Nov;171(3):1231-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Gohma H, Kimura K, Wedekind D, Hedrich HJ, Serikawa T.
                                                                                                                                                 The rat pink-eyed dilution (p) mutation: an identical intragenic deletion in                                                                         pink-eye dilute-coat strains and several Wistar-derived albino                                                                                                                                                 strains.
                                                                         Mamm Genome. 2005 Sep;16(9):712-9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Morimura K, Nomoto T, Namiki C, Hamada S, Fukushima S, Sugimura T,                                                                                                                                                                                                                         Serikawa T, Ushijima T.
                                                                         Sparse and wavy hair: a new model for hypoplasia of hair follicle and mammary glands on rat chromosome 17.
                                                                         J Hered. 2005 Jul-Aug;96(4):339-45.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuwamura M, Muraguchi T, Matsui T, Ueno M, Takenaka S, Yamate J, Kotani T,                                                                                                                                                 Kuramoto T, Guénet JL, Kitada K, Serikawa T.
                                                                         Mutation at the Lmx1a locus provokes aberrant brain development in the rat.
                                                                         Brain Res Dev Brain Res. 2005 Mar 31;155(2):99-106.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Mashimo T, Voigt B, Kuramoto T, Serikawa T.
                                                                         Rat Phenome Project: the untapped potential of existing rat strains.
                                                                         J Appl Physiol. 2005 Jan;98(1):371-9.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        2004

                                                                                                                                                                                                                                                                                                                                                                                                                        Nature Correspondence                                                                        

                                                                                                                                                                                                                        Serikawa T.
                                                                         Colourful history of Japan's rat resources.
                                                                         Nature 2004 May 6;429(6987):15.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuramoto T, Kuwamura M, Serikawa T.
                                                                         Rat neurological mutations cerebellar vermis defect and hobble are caused by mutations in the netrin-1 receptor gene Unc5h3.
                                                                         Brain Res Mol Brain Res.2004 Mar 30;122(2):103-8.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Tokuda S, Kuramoto T, Serikawa T.
                                                                         PCR-based genotyping of the rat Atrn(mv) mutation.
                                                                         Exp Anim. 2004 Jan;53(1):73-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                                        Kuwamura M, Ando Y, Takada A, Kanehara T, Yamate J, Kotani T, Takeshita S,                                                                                                                                                 Kanbori M, Kitada K, Serikawa T.
                                                                         Rat mutations cvd and hob with cerebellar malformations map to chromosome 2.
                                                                         Exp Anim. 2004 Jan;53(1):21-6.

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                   

                                                                                                                                                                                                   

                                                                                                                                                                                           

                                                                                                                                                                                       

                                                                                                                 

                                                                        

                                                                           

               

                                                                           

               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                                                                           

                                                                                                                                                                                                               

                                                                                                                                                    

                                                                                                                                                        

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                                                                                           

                                                                                                                                               

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

            

            

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

       

       

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

                                                                   

       

       

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

   

                                                                               
                                                                               

論文掲載(国内)

                                                                                                                                           

                   

                                                2020

                   

濵田和弥、森田健斗、本多新
     ラット体外受精とゲノム編集
     LABIO21, No. 80, 9-12, 2020.

                   

                                                2019

                   

浅野雅秀
     ナショナルバイオリソースプロジェクト「ラット」(NBRP-Rat)の紹介
     LABIO21 No. 78 13, Oct 2019

守田昂太郎
     ナショナルバイオリソースプロジェクト「ラット」の活動について
     LABIO21 No. 77 39, Jul 2019

                   

                                                2017

                                                                               

田中美有
     がん研究にも役立つ多様なラットリソース: ナショナルバイオリソースプロジェクト「ラット」(NBRP-Rat)のご紹介
     がん予防学会ニュースレター No. 94 2017 Dec.

                   

                                                2015

                   

庫本高志
     NBRP「ラット」―遺伝子改変ラットの利用と保存―
     BioPhilia 電子版 vol.4 No.2 77-83, 2015

                   

            2014

                     

真下知士
                         人工ヌクレアーゼによる新しい遺伝子改変動物の作製法
                         感染・炎症・免疫 44(2), 167-170, 2014

                   

吉見一人、金子武人、真下知士
     ラットにおけるゲノム編集技術革命
     実験医学 32(11), 1715-1720, 2014

                   

庫本高志
     近交系の意義と代表的なマウス・ラット近交系
     小児外科 46(6), 575-579, 2014

                                                                               

真下知士
     新しい遺伝子改変技術による肥満モデル動物の作成研究
     最新肥満症学 77-82, 2014

                   

磯谷綾子
     "ラット"って、どんな研究に使われているの?--第7回ラットリソースリサーチ研究会--
     実験医学 32(8), 1304-1307, 2014

                                                                               

吉見一人、金子武人、真下知士
     ラットにおけるTALENおよびCRISPR/Cas9を用いた遺伝子改変
     実験医学別冊 今すぐ始めるゲノム編集(山本卓/編)109-119, 2014

                   

真下知士
     ラットのゲノム編集技術を開拓
     Natureダイジェスト 11(4), 21, 2014

                                                                               

                                    2013

                                                                               

庫本高志
     実験用シロネズミの起源
     関西実験動物研究会会報 35, 60-65, 2013

                                                                               

真下知士
     重症免疫不全SCIDラットの作製
     医学のあゆみ 246(13), 1114-1115, 2013

                                                                               

真下知士、金子武人
     ラットにおける遺伝子改変技術の新展開
     細胞工学 32(5), 564-569, 2013

                   

芹川忠夫
     実験用ネズミの起源と汎用化への道のり
     ファルマシア 49(8), 769-773, 2013

                                                                                 

庫本高志
                         「白ネズミ」から見えてきた実験用ラットの起源
                         感染 炎症 免疫 43(3) p71-74

                                                                               

芹川忠夫
     実験用ラット研究の進展
     岡山実験動物研究会報 29, 44-47, 2013

                   

金子 武人
     フリーズドライ精子保存法 -液体窒素不要の新規遺伝資源保存法の開発-
     医学のあゆみ 244(7), 628-629, 2013

                                                                               

庫本高志
     実験用シロネズミの起源
     バイオリソースニュースレターBioResource now! Vol.7 No.11 p1-2

                                                                                 

                                  2012

                   

芹川 忠夫
     疾患モデルの作製と利用-糖尿病・肥満・感染症〈series モデル動物利用マニュアル〉
     疾患モデルの作製と利用-がん〈series モデル動物利用マニュアル〉
     監修、エル・アイ・シー

                                                                               

真下 知士、芹川 忠夫
     ジンクフィンガーヌクレアーゼ(ZFN)
     細胞工学Vol31(3), p296-301

                                                                               

金子 武人、芹川 忠夫
     Birth of Baby Derived from Egg Fertilized with Freeze-Dried Sperm. Successful Long-term Preservation of Sperm by Freeze-drying.
     Kyoto University Research Activities 2012 Vol. 2, No. 2, June, P 28.

                                                                               

庫本 高志
     Demyelinationn ラット:脱髄の最新疾患モデル
     遺伝子医学MOOK22 最新疾患モデルと病態解明、創薬応用研究、細胞医薬創製研究の最前線 pp68-73

                   

真下 知士
     ジンクフィンガーヌクレアーゼ(ZFN)による重症免疫不全(SCID)ラットの作製と創薬応用研究への試み
     最新疾患モデルと病態解明,創薬応用研究,細胞医薬創製研究の最前線、遺伝子医学MOOK 22号、p44-51

                                                                               

金子 武人
     FOCUS:凍結乾燥したネズミの精子から子が誕生
     Newton 2012年7月号 P 14

                                                                                 

金子 武人
                         10年ひと仕事 -フリーズドライ精子保存法開発への道-
                         BioResource Now! 2012年6月号 Vol. 8 P 1-2

                                                                               

金子 武人
     化学掲示板「長期保存のフリーズドライ精子から子が誕生」
     化学 2012年6月号 Vol. 67 P 73

                                                                               

真下 知士、芹川 忠夫
     ジンクフィンガーヌクレアーゼによる遺伝子改変動物の作製
     Medical Science Digest Vol38(1), p10-11

                   

                                                                               2011

                   

真下 知士
     新しい遺伝子改変技術「ジンクフィンガーヌクレアーゼ(ZFN)」
     生物と化学、日本農芸化学会編、p220-222

                                                                               

真下 知士
     (ZFN)によるノックアウトラットの作製方法
     生物機能モデルと新しいリソース・リサーチツール(モデル動物利用マニュアル)編、p494-499

                                                                               

真下 知士
     ENUミュータジェネシスによる標的遺伝子変異ラットの作製方法
     生物機能モデルと新しいリソース・リサーチツール(モデル動物利用マニュアル)編、p487-493

                                                                               

            2010

                   

芹川 忠夫
     バイオリソース・ラットの歴史と展望―福をもたらす実験動物
     Vol.28 No.1 103-107, 2010

                                                                                 

                                  2009

                     

庫本 高志
                         リコンビナント近交系ラットとBACライブラリー
                         生物機能モデルと新しいリソース・リサーチツール pp469-472, 2009

                                                                               

庫本 高志
     江戸の、そして平成の『養鼠玉のかけはし』
     Biophilia Vol.5 No.3 58-61, 2009

                                                                               

芹川 忠夫
     NBRP(ナショナルバイオリソースプロジェクト)紹介 ラット―ヒトのモデルとしての活用
     Biophilia Vol.5 No.1 50-54 2009

  

                     

          2008

                   

丸 栄一、菅谷 佑樹
     ギャップジャンクションとてんかん
     Clinical Neuroscience Vol.26 21-24 2008

                                                                               

            2007

                                                                               

芹川忠夫
     疾患モデル-ラットバイオリソース
     脳神経外科速報 第17巻11号 1312-1319, 2007

                                                                               

滝澤明子、Birger Voigt、鶴見東志子、真下知士、庫本高志、芹川忠夫
     NBRP-Ratの概要とラット胚・精子の保存状況
     実験動物技術 第42巻1号 35-40, 2007

                                                                               

芹川忠夫
     ナショナルバイオリソースプロジェクト「ラット」リソースセンター紹介 NO.16
     BioResource now! Vol.3, 2007

                   

            2006

                   

芹川忠夫
     連載 使ってみたい!バイオリソース大集合 第2回 ラット:ラットリソースとユニークな研究
     細胞工学 25(12):1456-1459, 2006

                                                                               

芹川忠夫
     まるごと生き物大特集:バイオリソースプロジェクト「ラット」
     遺伝 60(5): 18-19, 2006

                                                                               

真下知士、Birger Voigt、直井国子、山崎賢一、中西聡、庫本高志、芹川忠夫
     ラットフェノームプロジェクト:NBRP-Ratに寄託されたラット系統の体系的特性評価
     疾患モデル通信 No.21 2006.3

                                                                               

            2005

                                                                               

真下知士、左近上博司、西森司雄、Birger Voigt、直井国子、鶴見東志子、山崎賢一、中西聡、庫本高志、芹川忠夫
     ラットフェノームプロジェクト:ラット既存系統の体系的特性評価
     日本疾患モデル学会記録21: 17-21, 2005

                   

真下知士、直井国子、庫本高志、芹川忠夫
     実験用ラットの有用性 - ナショナルバイオリソースプロジェクト「ラット」-
     遺伝 59(3):79-84, 2005

                                                                               

            2004

                   

芹川忠夫
     ラットのゲノム全塩基配列解読とわが国のラットリソース
     蛋白質核酸酵素49(13): 2139-2148, 2004

                   

丸 栄一、洲鎌 秀永、芝崎 保
     てんかんの病態生理 -抑制から発作へ-
     神経研究の進歩 第48巻6号 917-927 2004

                   

            2003

                     

芹川忠夫
                         「珍翫鼠育草」の鼠はマウスかラットかネズミか
                         関西実験動物研究会会報、24:14-18. 2003

                   

庫本高志、芹川忠夫
     動き出した米国と日本のラットリソースセンター
     疾患モデル通信 No15 2003.2

                                                                               

NBRP-Ratに関する学会等での発表


2024

はじめに:第5期NBRP ラットの後半に向けての取り組み
 第18回ラットリソースリサーチ研究会(京都大学)2025.2.7

NBRP合同展示
 第47回日本分子生物学会年会(福岡市)2024.11.27-29

NBRP合同展示
 第97回日本生化学会大会(横浜市)2024.11.6-8

NBRP合同展示
 BioJapan 2024(横浜市)2024.10.9-11

第54回日本腎臓学会西部学術大会(姫路市)2024.10.5-6

NBRP合同展示
 第71回日本実験動物学会総会(京都市)2024.5.29-31

新しい時代の実験動物バイオリソース
 第71回日本実験動物学会総会(京都市)2024.5.29-31

2023

NBRP合同展示
 日本農芸化学会2024年度大会(東京)2024.3.24-27

東大医科学研究所におけるラットリソースについて
 第17回ラットリソースリサーチ研究会(京都大学)2024.1.26

はじめに:第5期NBRPラットとCreラットの特性解析
 第17回ラットリソースリサーチ研究会(京都大学)2024.1.26

NBRP合同展示
 第52回日本免疫学会学術集会(千葉市)2024.1.17-19

NBRP合同展示
 第46回日本分子生物学会年会(神戸市)2023.12.6-8

Model Animal Conference, Seoul, Korea, Oct. 2023

NBRP合同展示
 BioJapan 2023(横浜市)2023.10.11-13

Introduction of NBRP-Rat and behavioral analysis of mini-rats generated by genome-editing
 9th Asian Federation of Laboratory Animal Science Associations (AFLAS) Congress 2023, Jeju, Korea, Sep. 13-15, 2023

NBRP合同展示
 第46回日本神経科学大会(仙台市)2023.8.1-4

NBRPラットに寄託されている先天異常系統とラット生殖工学技術の開発
 第63回日本先天異常学会学術集会(つくば市)2023.7.28-30

NBRP合同展示
 第63回日本先天異常学会学術集会(つくば市)2023.7.28-30

NBRP合同展示
 第50回日本毒性学会学術年会(横浜市)2023.6.19-21

Ghr欠損ラットの表現型解析
 第70回日本実験動物学会総会(つくば市)2023.5.24-26

NBRP-Rat in Japan and development of rat reproductive technologies
 The 36th International Mammalian Genome Conference (IMGC 2023), Tsukuba, Mar. 28-31, 2023

NBRP合同展示
 日本薬学会第143年会(札幌市)2023.3.25-28

ナショナルバイオリソースプロジェクト「ラット」(NBRP-Rat)~生理学研究に役立つラットリソースのご紹介~
 日本生理学会第100回記念大会展示(京都市)2023.3.14-16

NBRP-Ratにおける凍結保存精子からの個体復元法
 第16回ラットリソースリサーチ研究会(京都大学)2023.1.27

2022

NBRP合同展示
 第45回日本分子生物学会年会(千葉市)2022.11.30-12.2

The fifth term of the National BioResource Project - Rat in Japan
 The 13th International Meeting of the Asian Network of Research Resource Centers (ANRRC 2022), Online, Nov. 8-9, 2022

Introduction of NBRP-Rat in Japan and Development of Rat Reproductive Technologies
 Korea Animal Model Archive (KAMA) Workshop, Seoul, Nov. 2, 2022

NBRP合同展示
 BioJapan 2022(横浜市)2022.10-12-14

Introduction of rat resources useful for cancer research
 第81回日本癌学会学術総会(横浜市)2022.9.29-10.1

NBRP合同展示
 日本動物学会第93回早稲田大会(東京)2022.9.8-10

ナショナルバイオリソースプロジェクト「ラット」(NBRP-Rat)
 第76回日本栄養・食糧学会大会展示(西宮市)2022.6.11-12

第4期ナショナルバイオリソースプロジェクト「ラット」の成果
 第69回日本実験動物学会総会(仙台市)2022.5.18-20

NBRP「ラット」:様々な研究に役立つ世界最高水準のラットリソースのご紹介
 第95回日本薬理学会年会展示(福岡市)2022.3.7-9

ラットリソース業務の効率化と利用者拡大に向けた生殖工学技術の開発
 第15回ラットリソースリサーチ研究会(Web開催)2022.2.18

はじめに:NBRPラット第4期の総括と第5期に向けて
 第15回ラットリソースリサーチ研究会(Web開催)2022.2.18

2021

NBRP「ラット」:様々な研究に役立つ世界最高水準のラットリソースのご紹介
 第44回日本分子生物学会年会 附設展示会(NBRPコーナー)(横浜市)2021.12.1-3

ナショナルバイオリソースプロジェクト「ラット」
 BioJapan 2021展示(横浜市)2021.10.13-15

Introduction of rat resources useful for cancer research
 第80回日本癌学会学術総会(横浜市)2021.9.30-10.2

ナショナルバイオリソースプロジェクト「ラット」の活動と生殖工学研修のご紹介
 第68回日本実験動物学会総会(Web開催)2021.5.19-21

ナショナルバイオリソースプロジェクト「ラット」(NBRP-Rat)
 第2回医薬系研究交流サロン(Web開催)2021.4.19-21

Growth hormone receptorを欠損させたマイクロミニラットの開発
 第14回ラットリソースリサーチ研究会(Web開催)2021.1.29

はじめに:コロナ禍での第4期NBRP-Ratの取り組み
 第14回ラットリソースリサーチ研究会(Web開催)2021.1.29

2020

様々な研究に役立つ世界最高水準のラットリソースのご紹介
 第43回日本分子生物学会年会 附設展示会(NBRPコーナー)(オンライン開催)2020.12.2-4

NBRP-Ratのバイオリソースとしての活動と生殖工学技術の紹介
 第67回日本実験動物学会総会(誌上開催)

「ラット」の生殖工学技術開発は「マウス」にどこまで追いついたのか?
 第13回ラットリソースリサーチ研究会(京都大学)2020.2.21

第4期NBRP-Ratの後半に向けての取り組み
 第13回ラットリソースリサーチ研究会(京都大学)2020.2.21

NBRP「ラット」の事業と生殖工学技術の紹介
 第1回医薬系研究交流サロン(京都大学)2020.1.31

                                                   

                                                            2019

   

様々な研究に役立つ世界最高水準のラットリソースのご紹介
 第42回日本分子生物学会大会 附設展示会(NBRPコーナー)(福岡市)2019.12.3-6

Useful rats in the National BioResource Project-Rat for cancer research
 第78回日本癌学会学術総会(京都市)2019.9.26

NBRP「ラット」の神経科学研究に役立つリソースのご紹介
 第42回日本神経科学大会(新潟市)2019.7.25-28

                                                                

疾患のプロテオーム解析に有用なNBRP「ラット」リソースのご紹介
 日本プロテオーム学会2019年大会 附設展示会(NBRPコーナー)(宮崎市)2019.7.24-27

The forth term of the National BioResource Project-Rat in Japan and development of rat reproductive technologies
 Complex Traits Consortium / Rat Genomics 17th Annual Meeting (California on the University of California San Diego campus) 2019.6.8-11

                   

世界最高水準のラットリソース拠点(NBRP-Rat)より有用なゲノム編集ラットのご紹介
 日本ゲノム編集学会4回大会(江戸川区)2019.6.3-5

                   

第4期ナショナルバイオリソースプロジェクト「ラット」の成果と有用ラットのご紹介
 第66回日本実験動物学会総会(博多区)2019.5.15-17

                   

世界最高水準のラットリソースのご紹介
 日本農芸化学大会2019年度大会 附設展示会(NBRPコーナー)(世田谷区)2019.3.24-27

                                                   

                                                            2018

                   

THE FORTH TERM OF THE NATIONAL BIORESOURCE PROJECT-RAT IN JAPAN
 8th AFLAS         Congress 2018 (インド) 2018.11.28-12.1

                   

世界最高水準のラットリソースのご紹介
 第41回日本分子生物学会年会 附設展示会(NBRPコーナー)(神戸市)2018.11.28-30

                   

神経科学研究に役立つNBRP-Ratの活用
 第41回日本神経科学大会 附設展示会(神戸市)2018.7.26-28

                   

世界最高水準のラットリソース拠点:第4期ナショナルバイオリソースプロジェクト「ラット」
 第65回日本実験動物学会総会(富山市)2018.5.16-18

                   

世界最高水準のラットリソース拠点:第4期ナショナルバイオリソースプロジェクト「ラット」
 日本農芸化学会 2018年大会(名古屋市)2018.3.16-18

                   

世界最高水準のラットリソース拠点としてのナショナルバイオリソースプロジェクト「ラット」
 第34回日本毒性病理学会学術集会(那覇市)2018.1.24-26

                                                   

                                                            2017

                   

ラットの特性:遺伝子改変時代を見据えて
 2017 遺伝研研究会「マウスとラットで拓く新しい比較実験動物学」(三島市)2017.12.14-15

                   

ナショナルバイオリソースプロジェクト「ラット」と比較実験動物学
 2017         遺伝研研究会「マウスとラットで拓く新しい比較実験動物学」(三島市)2017.12.14-15

                   

世界最高水準のラットリソース拠点:第4期ナショナルバイオリソースプロジェクト「ラット」
 第40回日本分子生物学会         特別企画「NBRP実物付きパネル展示」(神戸市)2017.12.6-8

                   

X-SCIDラットにおけるラットポリオーマウイルス2感染症
 第160回日本獣医学会学術集会 (鹿児島市)2017.9.13-15

                   

発癌研究に役立つ多様なラットリソース
 第32回発癌病理研究会(大津市)2017.8.23-25

                   

神経科学分野で有用なラットリソースのご紹介
 第40回日本神経科学大会 大会附設展示会 (千葉市)

                   

The forth term of the National BioResource Project-Rat in Japan
 15th Annual         Meeting of the Complex Trait Community in collaboration with the Rat     Genomics     Community(アメリカ)2017.6.13-17

                   

世界最高水準のラットリソース拠点:ナショナルバイオリソースプロジェクト「ラット」
 日本ゲノム編集学会第2回大会附設展示会(吹田市)         2017.5.29-30

                   

世界最高水準のラットリソース拠点:ナショナルバイオリソースプロジェクト「ラット」
 第64回日本実験動物学会総会(郡山市)2017.5.25-27

                   

            2016

                   

ナショナルバイオリソースプロジェクト「ラット」の魅力
 第39回日本分子生物学会         特別企画「NBRP実物付きパネル展示」(横浜市)2016.11.30-12.2

                   

NATIONAL BIORESOURCE PROJECT-RAT IN JAPAN
 7th AFLAS Congress 2016 (シンガポール)         2016.11.7-11

                   

The 3rd Term of the National BioResource Project-Rat in Japan.
 The 8th         ANRRC International Meeting (京都市)2016.9.20-22

                   

世界最高水準のラットリソース拠点:ナショナルバイオリソースプロジェクト「ラット」
 第63回日本実験動物学会総会(川崎市)2016.5.18-20

                   

2015

                   

The Third Term of the National BioResource Project–Rat in Japan
 Rat         Genomics & Models meeting(アメリカ)

                   

世界最高水準のラットリソース拠点:NBRP-Rat
 BMB2015 第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会 2015.12.1-3

                   

第3期ナショナルバイオリソースプロジェクト「ラット」
 第62回日本実験動物学会総会(京都市)2015.5.28-30

                     

                                  2014

                   

The Third Term of the National BioResource Project–Rat in Japan
 Rat         Genomics & Models meeting 2014(Hinxton, UK)2014.12.1-4

                   

そうだ、ラットを使おう
 第37回日本分子生物学会(横浜市)2014.11.25-27

                   

世界最高水準のラットリソース拠点
 第61回日本実験動物学会総会(札幌市)2014.5.15-17

                   

            2013

                   

The Third Term of the National BioResource Project–Rat in Japan
 Rat         Genomics & Models meeting 2013(Cold Spring Harbor, US)2013.12.11-14

                                                                               

世界最高水準のラットリソース拠点
 第36回日本分子生物学会年会(神戸市)2013.12.3-5

                   

第3期ナショナルバイオリソースプロジェクト「ラット」
 第49回高血圧関連疾患モデル学会学術総会(東京)2013.9.6-7

                   

第3期ナショナルバイオリソースプロジェクト「ラット」の魅力
 第60回日本実験動物学会総会(つくば市)2013.5.15-17

                                                                               

実験用シロネズミの起源
 第117回関西実験動物研究会(京都市)2013.3.1

                                                                               

National BioResource Project for the Rat in Japan
 11th Transgenic         Technology Meeting(Guangzhou, China)2013.2.25-27

                                                                               

                                    2012

                   

第3期ナショナルバイオリソースプロジェクト「ラット」
 第35回日本分子生物学会年会(博多市)2012.12.11-14

                                                                               

The Third Term of the National BioResource Project–Rat in Japan
 Rat         Genomics & Models meeting 2012(Cambridge, UK)2012.12.3-6

                   

Successful long-term preservation of rodent sperm by freeze-drying
 4th         congress of the asia pacific initiative on reproduction(大阪市)2012.8.30-9.2

                                                                               

世界のラットリソース拠点 ナショナルバイオリソースプロジェクト「ラット」
 第59回日本実験動物学会総会(別府市)2012.5.24-26

                                                                               

            2011

                   

ナショナルバイオリソースプロジェクト「ラット」の現状と展望
 日本遺伝学会第83回大会(京都市)2011.9.20-23

                                                                               

Fertility of rat sperm after freeze-drying
 44th Annual Meeting of the         Society for the Study of Reproduction(Portland, Oregon)2011.7.31-8.4

                                                                                 

Rat ENU mutagenesis - KURMA, an update
 EURATRANS 1st annual meeting      2011(Stresa,                         Italy)2011.5.30-31

                                                                               

ナショナルバイオリソースプロジェクト「ラット」の現状と展望
 第58回日本実験動物学会総会(東京都)2011.5.25-27

                     

          2010

                   

NBRP「ラット≪基盤技術整備プログラム≫」:ラット精子に関する基盤技術の整備
 第33回日本分子生物学会年会(神戸市)2010.12.7-10

                   

NBRP「ラット」:世界拠点としてのNBRP-Ratの現状
 第33回日本分子生物学会年会(神戸市)2010.12.7-10

                   

NBRP-Rat: The worldwide rat resource center
 The XVIIIth International         Workshop on Genetic Systems in the Rat(京都市)2010.11.30-12.3

                   

National BioResource Project-Rat -an update
 EURAT2010(Berlin)2010.5.27-28

                   

世界拠点としてのナショナルバイオリソースプロジェクト「ラット」
 第57回日本実験動物学会総会(京都市)2010.5.12-14

                                                                               

            2009

                   

ヒト疾患モデル開発のためのラットENUミュータントアーカイブ
 第32回日本分子生物学会年会(横浜市)2009.12.9-12

                   

ナショナルバイオリソースプロジェクト「ラット」:世界拠点としてのNBRP-Rat
 第32回日本分子生物学会年会(横浜市)2009.12.9-12

                   

National BioResource Project–Rat – an update
 Rat Genomics & Models(米国Cold         Spring Harbor)2009.12.2-5

                                                            ショウジョウバエ遺伝資源センター設立10周年記念行事 バイオリソースシンポジウム(京都市)2009.10.23

  

National BioResource Project - Rat in Japan and related activities
1st ANRRC & Asian Chapter Meeting of ISBER (Korea, Seoul) 2009.9.22-25

                                                                               

 

                   

                                                             

                   

 

                                                                               

 

                                                                               

 

                                                                               

    

                   

    

                                                                               

    

                                                                               

    

                   

    

                                                                               

Genetic Dissection of the LEXF/FXLE Recombinant Inbred Strains
 第13回国際SHRシンポジウム(チェコ・プラハ)2008.6.20-22

                                                                               

    

                   

   

                                                                               

   

                   

                                                             

                     

   

                   

   

                   

   

                                                                               

   

                                                                               

   

                                                                               

ENUミュータジェネシスにより作製されたScn1a遺伝子変異ラット
 第30回日本神経科学大会(横浜市)2007.9.10-12

                   

ナショナルバイオリソースプロジェクト「ラット」
 第24回日本疾患モデル学会(つくば市)2007.8.31-9.1

                                                                               

NBRPラットリソースのデータベース
 第15回筑波実験動物研究会(つくば市)2007.6.14

                                                                               

ナショナルバイオリソースプロジェクト「ラット」の事業成果
 第54回日本実験動物学会総会(江戸川区)2007.5.23-25

                   

動物を用いる試験と研究
 第54回日本実験動物学会総会(江戸川区)2007.5.23-25

                   

生命科学を支える 実験動物学と動物実験技術
 日本実験技術者協会九州支部 創立30周年記念講演会2007.4.7-8

                   

Japan-European Collaborations in Rat Genomics
 EURATools 1st Annual     Meeting(チェコ・プラハ)2007.2.26-28

                   

            2006

                     

『ラット胚・精子の超低温保存と個体復元技術マニュアル(DVD版)』の作製
 第92回関西実験動物研究会研究会(京都市)2006.12.8

                                                                                                                                                                                                    

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」:ラットリソースの世界拠点
第56回日本実験動物学会総会(さいたま市)2009.5.14-16The                                               National Bio Resource Project for the Rat in Japan - au                        update
                     XVIth International Workshop on Rat Genetic                        Systems(オーストラリア                        Melbourne)2006.12.1-2

                                                                                                                                                                                                       

                                       

NBRP-Ratにおける特性検査:既存系統における新たな特性の発見
                                                                      第21回日本疾患モデル学会総会(京都市)2004.11 疾患モデルラットの活用
                                                                       第51回日本実験動物学会総会(長崎)2004.5 2008The LEXF/FXLE rat                         recombinant inbred strain set: a powerful tool for genetic                                                 dissection of complex traits
                                               XVIth International                         Workshop on Rat Genetic                         Systems(オーストラリア Melbourne)2006.12.1-2

                                                                                                                                                                                                       

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」:ラットリソースの世界拠点
第31回日本分子生物学会年会(神戸市)2008.12.9-12パネルディスカッション:日本実験動物学会と日本疾患モデル学会の将来展望
                                                                       第23回日本疾患モデル学会(群馬県渋川市)2006.11.30
Rat                                                 Genomics &                         Models(英国Hinxton)2008.12.3-6実験用ラットの収集・保存・提供事業の有用性
                                                                       日本遺伝学会第78回大会 ナショナルバイオリソースプロジェクト                         シンポジウム(つくば市)2006.9.25-27

                                                                                                                                                                                                       

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」における胚・精子の保存状況
                                                                                               第40回日本実験動物技術者協会、NBRPラット共催「ラット生殖技術の進歩」シンポジウム(京都市)2006.10.28

                                                                                                                                                                                                       

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」:ラットBACクローンライブラリの基盤整備
第31回日本分子生物学会年会(神戸市)2008.12.9-12National                                                 Bio Resource Project for the Rat (NBRP-Rat) in Japan
                                                                       第12回国際SHRシンポジウム(京都市)2006.10.20-21

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト 「ラット」 について
ラット生殖工学ワークショップ(相模原市)2008.7 ラット FXLE/LEXF                                                 RI系統セットの活用
                                               第20回日本糖尿病動物研究会(千代田区)2006.2.9-10

                                                                                                                                                                                                       

The National Bio Resource Project for the Rat in Japan - an update                                                                                                                                                                                             2005

                                                                                                                                                                                                       

第2期ナショナルバイオリソースプロジェクト「ラット」の現状報告
第55回日本実験動物学会総会(仙台市)2008.5.15-17 The National                                                 Bio Resource Project for the Rat in Japan
                                               Rat                         Genomics & Models(米国Cold Spring                         Harbor)2005.12.8-11

                                                                                                                                                                                                       

NBRP-Ratの「過去」「現在」「未来」
第100回関西実験動物研究会研究会(京都市)2008.12.5 The LEXF/FXLE rat                                                 recombinant inbred strain set: a newly enhanced tool for                         genetic dissection of                         complex traits
                                                                                               第2回アジア実験動物学会連合(AFLAS)学術集会(韓国Jeju)2006.8.29-9.1 日本における疾患モデルラット研究の流れ
第55回日本実験動物学会総会(仙台市)2008.5.15-17                                                 ラットフェノームプロジェクト:既存ラット系統の有用性
                                                                       第88回関西実験動物研究会研究会(京都市)2005.12.2

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」
NBRPキックオフシンポジウム(千代田区)2008.3.10 NBRP-Rat                                                 における遺伝子診断システム
                                              第88回関西実験動物研究会研究会(京都市)2005.12.2

                                                                                                                                                                                                             

Latest activities of the National Bio Resource Project for the Rat in Japan
the                                                 3rd AFLAS congress(中国 北京)2008.9.17-19                         ナショナルバイオリソースプロジェクト「ラット」:新たな統合研究基盤
                                                                       第53回日本実験動物学会総会(神戸市)2006.5.11-13 2007ラットリソースとデータベースの拡充
                        第28回日本分子生物学会年会                                                   特別企画「ナショナルバイオリソースプロジェクト(NBRP)」(福岡市)2005.12.7-10

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」:ラットリソースの世界拠点
第30回日本分子生物学会年会(横浜市)2007.12 A Set of                                                 Highly Informative Rat SSLP Markers and Genetically                         Defined Rat Strains in the                         NBRP-Rat
                                                                                               第19回国際マウスゲノム会議(IMGC)(フランスStrasbourg)2005.11.4-8

                                                                                                                                                                                                       

標的遺伝子変異ラット作製のためのENUミュータントアーカイブ
高温耐性FOKラットシンポジウム2008(名古屋市)2008.9.13                                                 NBRP-Ratで収集されたラット系統の系統樹
                                                                       第53回日本実験動物学会総会(神戸市)2006.5.11-13 The National Bio Resource Project for the Rat in Japan – An Update
Rat                                                 Genomics & Models(米国Cold Spring Harbor)2007.12.6-9                         ナショナルバイオリソースプロジェクト「ラット」の利用方法
                                                                       第41回高血圧関連疾患モデル学会学術総会(札幌市)2005.9.2-3

                                                                                                                                                                                                       

National BIoResource Project – Rat
第21回国際哺乳類ゲノム会議(IMGC)(京都市)2007.10.21-11.1                                                 The National Bio Resource Project for the Rat in Japan:                         SystematicAccumulation,                         Storage and Provision of                         Valuable Rat Strains
                                                                       韓国実験動物科学国際シンポジウム(韓国Seoul)2005.6.3-4

                                                                                                                                                                                                       

日本における疾患モデルラット研究の流れ
日本動物学会第79回大会特別企画 ナショナルバイオリソースプロジェクト(NBRP)紹介                                                 シンポジウム・展示(福岡市)2008.9.5-7 世界最大規模のラットリソースとラットを用いた試験研究の新展開
                                                                                               NBRPシンポジウム「バイオリソースとライフサイエンス研究最前線」(千代田区)2006.3.9 Rat genomics, genetics and resources
第21回国際哺乳類ゲノム会議(IMGC)(京都市)2007.10.21-11.1                                                 動物実験センターにおける生殖・発生工学技術の現状と展望 ナショナルバイオリソースプロジェクト「ラット」
                                                                                               第31回国立大学動物実験施設協議会サテライトミーティング(広島市)2005.5

                                                                                                                                                                                                       

SHR関連系統を含むラット系統の網羅的SNP解析
第43回高血圧関連疾患モデル学会学術総会(大阪市)2007.9.7-8 ラットゲノムシークエンス、                                                 比較ゲノム、そして ラットモデルの利用
                                                                       第52回日本実験動物学会総会シンポジウム(江戸川区)2005.5.18-20

                                                                                                                                                                                                       

NBRP-Ratにおけるフェノムプロジェクト
第52回日本実験動物学会総会シンポジウム(江戸川区)2005.5.18-20

                                                                                                                                                                                                       

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」と糖尿病モデルラット系統
                                                                       第19回日本糖尿病動物研究会年次学術集会(京都市)2005.2.8-9                                                                                                                                                                

                                                                                                                                                                                                       

 

                                                                                                                                                                                                       

                    2004

                                                                                                                                                                                                       

                                                                                                                                                                                                       

 

                                                                                                                                                                                                       

                                                                                                                                                                                                       

NBRP-Rat 収集系統における Agouti とRed-eyed dilution のプロファイル
                                                                      第84回関西実験動物研究会研究会(京都市)2004.12 ラットフェノームプロジェクト:既存系統における新たな特性の発見
                                                                      第84回関西実験動物研究会研究会(京都市)2004.12

                                                                                                                                                                                                       

 

                                                                                                                                                                                                       

 NBRP-Ratで収集されたラット系統のゲノムプロファイル
                                                                      第84回関西実験動物研究会研究会(京都市)2004.12

                                                                                                                                                                                                       

ラットリソースの収集・保存・提供、そしてフェノームプロジェクト
                                                                       NBRPラット公開シンポジウム「新しい展開を迎えるラットリソース」(京都市)2004.11

                                                                                                                                                                                                       

ナショナルバイオリソース プロジェクトの進捗状況
                      第84回関西実験動物研究会研究会(京都市)2004.12

                                                                                                                                                                                                       

 

                                                                                                                                                                                                       

ナショナルバイオリソースプロジェクト「ラット」
                      第27回日本分子生物学会年会(神戸市)2004.12

                                                                                                                                                                                                       

 

                                                                                                                                                                                   

 

                                                                                                                                                                                   

ナショナルバイオリソースプロジェクト「ラット」
                       第51回日本実験動物学会総会(長崎)2004.5

                                                                                                                                                                                                       

NBRP-Ratにおけるゲノム検査:収集されたラット系統のゲノムプロファイル
                                                                      第21回日本疾患モデル学会総会(京都市)2004.11 ナショナルバイオリソースプロジェクト「ラット」の推進
                                                                       公私立大学実験動物施設協議会総会 第10回シンポジウム2004.5

                                                                                                                                                                                                       

疾患モデルラットの活用
                       公私立大学実験動物施設協議会総会 第10回シンポジウム2004.5

                                                                                                                                                                                                       

                                                                                                                                                                                                       

 

                                                                                                                                                                                                             

                                                                                                                                                                                                             

ラットリソースの収集・保存・提供、そしてフェノームプロジェクト
                                                                      第21回日本疾患モデル学会総会(京都市)2004.11 National Bio Resource Project - Rat
                                                                                               第11回国際自然発症高血圧ラットシンポジウム(米国Portland)2004.5 新しい展開を迎えるラットリソース
                      日本実験動物技術者協会関西支部                                                  平成15年度関西支部総会ならびに研究発表会2004.3                         
                                                                                                 第26回日本分子生物学会年会(神戸市)の特別企画「バイオリソース」2003.12

                                                                                                                                                                                                             

                                                                                                                                                                                                             

                                                 

                                                                                                                                                                                                             

ラットフェノームプロジェクト:既存系統の新たな可能性について
                                                                        第40回高血圧自然発症ラット(SHR)学会学術集会(大阪・守口市)2004.9                          ナショナルバイオリソースプロジェクト「ラット」
                                                                         文部科学省特定領域研究「発がんと防御」「個体レベル」若手ワークショップ(蓼科)2003.1

                                                                                                                                                                                                             

                                                  ナショナルバイオリソースプロジェクト「ラット」                                                                                                                          2002

                                                                                                                                                                                                             

ナショナルバイオリソースプロジェクト「ラット」とてんかんモデルラット系統
                                                                       第38回日本てんかん学会(静岡)2004.9 National Bio-Resource Project                          for the Rat in Japan
                                                                          第76回関西実験動物研究会2002.12.6

                                       

 ナショナルバイオリソースプロジェクト「ラット」
                                                                                                第19回日本疾患モデル学会ワークショップ「医学・生物学領域における日本のバイオリソースの現状と未来」2002.11

                                                                                                                                                                                                             

National Bio-Resource Project for the Rat in Japan
                                                                        第15回国際ラット遺伝システムシンポジウム(デンマークCopenhagen)2004.9 The National Bio Resource Project                                                                            for the Rat in Japan
                                                                          第17回国際マウスゲノム会議(IMGC)(ドイツBraunshweig)2003.11 The National Bio Resource Project                          for the Rat in Japan
                                                                          第14回国際ラット遺伝システムワークショップ(京都市)2002.10

                                                                                                                                                                                        

                                                                                                                         2003The National Bio Resource Project for the Rat in Japan
                                                                         第3回国際遺伝改変マウス病理学会(熊本市)2003.10 我が国のラットリソースの活用
                      第1回北海道実験動物研究会(札幌市)2004.9                                                   ナショナルバイオリソースプロジェクト「ラット」
                                                 NBRP発足シンポジウム2002.7

                                                                               
                                                                               

NBRP-Ratに関する新聞記事等

                                       
                   

                   

            2019

                   

産経新聞(2019/8/9)
「簡単で効率良い遺伝子改変ラット作出技術開発 京大など」にて、ラット体外受精に関する基盤整備プログラムの成果について紹介

                   

            2015

                   

京都新聞(2015/5/14)
「腕や頭部震える病気の原因遺伝子発見 京大、診断に光」にて、NBRP-Ratの成果について紹介

                   

            2014

                   

日刊工業新聞(2014/6/30)
     「京大、ゲノム編集でラットの毛色突然変異の修復に成功」にて、NBRP-Ratの成果について紹介

                   

日本経済新聞(2014/2/5)
     次代の創造手「フリーズドライで希少動物の精子保存」にて、NBRP-Ratの成果について紹介

                   

2013

                   

                   

                   

                   

                                                                               

朝日新聞(2013/4/9)
     「あの遺伝子を止めろ ノックアウト動物作り、手軽に」にて、NBRP-Ratの成果について紹介
     「シロネズミは全て同一祖先 京大、遺伝子を分析」にて、NBRP-Ratの成果について紹介

                                                                               

            2012

                                                                               

日刊工業新聞(2012/8/27)
     「ネズミに注目」にて、NBRP-Ratの成果について紹介

                                                                                 

京都新聞(2012/8/25)
     「白いラットの祖先はまだら 遺伝子変異が共通」にて、NBRP-Ratの成果について紹介NHK、日本テレビ、ABC朝日放送(2012/4/11)
                         「世界初“フリーズドライ”の精子でラット誕生」等、ラット精子に関する基盤技術整備プログラムの成果について紹介

                                                                               

TBSテレビ、日本テレビ、ABC朝日放送(2012/4/10)
     フリーズドライ技術で長期保存の精子からネズミの赤ちゃん」等、ラット精子に関する基盤技術整備プログラムの成果について紹介

                   

科学新聞(2012/5/11)
     「液体窒素不要 遺伝資源長期保存法を開発 京大の金子講師ら」にて、ラット精子に関する基盤技術整備プログラムの成果について紹介

                   

日刊工業新聞(2012/4/11)
     「フリーズドライ精子でラット誕生、長期保存が可能に、京大が成功」にて、ラット精子に関する基盤技術整備プログラムの成果について紹介

                   

日本経済新聞、朝日新聞、毎日新聞、讀賣新聞、京都新聞、産経新聞(2012/4/10)
     「フリーズドライ精子でラット出産 冷蔵保存5年 京大チーム成功」等、ラット精子に関する基盤技術整備プログラムの成果について紹介

                   

            2009

                   

朝日新聞(2009/2/2)
     「実験生物 国をあげて保存」にてNBRPについて紹介

                                                                               

日経産業新聞(2012/8/23)             2008

                   

読売新聞(2008/5/19)
     「ラットで病気モデル 効率よく作製」にてENUミュータジェネシス(NBRP寄託ラット)について紹介

                                                                               

朝日新聞(2008/5/12)
     「ラットも遺伝子改変 京大が提供システム」にてNBRP-RatとENUミュータジェネシス(NBRP寄託ラット)について紹介

                   

日経産業新聞(2008/5/1)
     「遺伝子変異ラット 京大、5000匹分作製 発症の仕組み解明へ」にてENUミュータジェネシス(NBRP寄託ラット)について紹介

                   

日刊工業新聞(2008/4/30)
     「ラット研究成果発表 京大で実施の文科省プロ 英科学雑誌に掲載」にてNBRP-Ratの成果がNature Genetics誌に掲載された旨を紹介

                                                                                 

朝日新聞(2012/8/17)
     「実験用シロネズミ祖先は日本に? 京大調査」にて、NBRP-Ratの成果について紹介京都新聞(2008/4/29)
                         「遺伝子変異ラット 5000匹分DNA・精子 京大グループ作製」にてENUミュータジェネシス(NBRP寄託ラット)について紹介

                   

            2007

                   

読売新聞(2007/4/16)
     「科学しようヨ!」にてNBRP-Ratを紹介

                                                                               

            2004

                   

朝日新聞(2004/9/22)
     「実験動物を考える1」にてNBRP-Ratを紹介

                                                                               

讀賣テレビ(2012/4/14)
     「世界初 フリーズドライで精子保存に成功!!」にて、ラット精子に関する基盤技術整備プログラムの成果について紹介産経新聞京都版(2004/5/21)
     「京で学ぶ24“実験用ラットの流通革命”」にてNBRP-Ratを紹介

                   

京都新聞(2004/5/20)
     「江戸期のラット本、ネイチャーに登場」にてNBRP-Ratを紹介

                                                                               
                                                                               

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