Japanese
 NBRP Rat No: 0005 Strain NameF344.ACI-Lmx1aqc/Kyo Commmon Name: F344.ACI-<i>Lmx1a<sup>qc</sup></i>, Queue courte rats
 Principal Investigator  Tadao Serikawa
 Organization   Graduate School of Medicine, Kyoto University Institute of Laboratory Animals
 Address  Yoshidakonoe-cho, Sakyo-ku

606-8501 Kyoto

 JAPAN
 Telephone  075-753-4360  Fax:  075-753-4409  serikawa@anim.med.kyoto-u.ac.jp
 Inbred Generations   N13F11 (May 2009) 
   
 Coat Color
 Deposition Status
 
 albino (c)
  Embryo      Sperm      Live Animals
 Usage Restrictions   
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene Lmx1a: LIM homeobox transcription factor 1 alpha
 Origin From ACI/Pas stock in Institute Pasteur, France. After 1998 introduced to Kyoto University, F344/NSlc backgrund congenic rats were established at Kyoto University. 
 Strain Characteristics short tail, neurologic disorder similar to dreher mouse, Mutation at the Lmx1a locus 
 Breeding Conditions Heterozygtes qc/+ are backcorssed with F344/NSlc. Maintained in heterozygous condition. 
 Genotyping Using markers linked with qc locus.

<a href="http://www.anim.med.kyoto-u.ac.jp/nbr/documents/PCR_Gene/Lmx1a_qc_en.pdf">Genotyping protocol for Lmx1a</a> 
 References  Kuwamura, M., Muraguchi, T., Matsui, T., Ueno, M., Takenaka, S., Yamate, J., Kotani, T., Kuramoto, T., Guenet, J-L., Kitada, K., Serikawa, T.
Mutation at the Lmx1a locus provokes aberrant brain development in the rat.
Brain Res Dev Brain Res 155(2):99-106, 2005