Strains

Japanese

NBRP Rat No: 0437

Strain Name: FOK/Ncu

Commmon Name: 古山ラット

Principal Investigator

Fujiya Furuyama

Organization

Nagoya City University Graduate School of Medical Sciences Department of Neuro-physiology & Brain science

Address

1 Kawasumi, Mizuho-ku, Nagoya

467-8601 Aichi

Japan

Telephone

052 853-8136

Fax: 052-842-3069

heiza-ff@med.nagoya-cu.ac.jp

Inbred Generations

F63+2 (May 2008)

Coat Color

Deposition Status

albino (c)

Embryo Sperm Live Animals

Usage Restrictions

The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Use of BIOLOGICAL RESOURCE shall be limited to collaborative researches with the DEPOSITOR. Detail of roles shall be discussed prior to start of the research.

Genetic Status

Inbred

Segregating

Congenic

Consomic

Recombinant

Coisogenic

Spont. Mutant

Transgene

Ind. Mutant

Others

Comercial Availability

Research Category

Diabetes Obesity

Neurobiology

Ophthalmology

Dentistry

Cardio- Hypertension

Oncology

Metabolism

Otorhinology

Immunology

Infectious Disease

Osteology

Internal Medicine

Dermatology

Reproduction

Development

Behavior

Hematology

Urology

Pharmacology

Others

Control Strains

Reporter gene Strains

Gene

Origin

Rat resistant to an ambient temperature of 42.5℃ were selected, inbred for more than 30 generations, and designated FOK (Furuyama, 1993). Wistar/MK, Jcl:Wistar, Wistar/MS, HOS:Wistar and Std:Wistar were used at first. (Mar 30, 2010)

Strain Characteristics

FOK shows heat tolerance (Furuyama, 1993) and cold tolerance (Yahata, 1999). (Mar 30, 2010)

Breeding Conditions

Genotyping

References

Furuyama F, Ohara K.
Genetic development of an inbred rat strain with increased resistance adaptation to a hot environment.
Am J Physiol. 265(4 Pt 2):R957-62, 1993.

Shido O, Sakurada S, Sugimoto N, Furuyama F, Nagasaka T.
Thermoeffector thresholds and preferred ambient temperatures of the FOK rat.
Am J Physiol. 274(3 Pt 2):R604-9, 1998.