English
 NBRP Rat No: 0698 系統名 :    DA.PVG.1AV1-(OT24.18-D10Rat93)/Kini 通称: DA.PVG.1AV1-Eae18b
 研究責任者:   Tomas Olsson
 所属機関名:  Karolinska Institutet
  住所:   〒L8:04, 

 Stockholm CMM, Karolinska University Hospital, 171 76,

 Sweden
 電話番号:  +46 8 51776258  Fax: +46 8 51775562  tomas.olsson@ki.se
 近交世代数:  Congenic strain was establiesh from the 10th generation advanced intercross line after 8 generations of backcrossing in 2008. Since then, the strain was kept as inbred.  
   
 毛色:  
 保存状況：
 
 Agouti
  胚           精子          生体
  利用条件：  利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する。
Adzemovic MZ, Ockinger J, Zeitelhofer M, Hochmeister S, Beyeen AD, Paulson A, Gillett A, Hedreul MT, Covacu R, Lassmann H, Olsson T, Jagodic M. Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats. PLoS One. 2012;7(7):e39794. Epub 2012 Jul 16. PMID: 22815714. 
 分類:   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    その他  
  コマーシャルブリーダー：   
 研究分野:   糖尿病・肥満    脳神経疾患   眼疾患    歯科疾患   循環器系疾患・高血圧
  がん・腫瘍   代謝、内分泌    耳鼻疾患   発生   感染症
   骨形態異常   消化器疾患   皮膚疾患    生殖器疾患   免疫・アレルギー疾患
   行動・学習   血液疾患   泌尿器疾患   薬理学   その他  
  対照動物   レポーター遺伝子動物  
 遺伝子: > 13.5 Mb
 由来:  
 特性など:  
繁殖・維持方法:  
 遺伝診断法:  
  参考文献: Jagodic M, Becanovic K, Sheng JR, Wu X, Bäckdahl L, Lorentzen JC, Wallström E, Olsson T. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. J Immunol. 2004 Jul 15;173(2):1366-73. PMID: 15240732.
Ockinger J, Stridh P, Beyeen AD, Lundmark F, Seddighzadeh M, Oturai A, Sørensen PS, Lorentzen AR, Celius EG, Leppä V, Koivisto K, Tienari PJ, Alfredsson L, Padyukov L, Hillert J, Kockum I, Jagodic M, Olsson T. Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Genes Immun. 2010 Mar;11(2):142-54. Epub 2009 Oct 29. PMID: 19865101.
Adzemovic MZ, Ockinger J, Zeitelhofer M, Hochmeister S, Beyeen AD, Paulson A, Gillett A, Hedreul MT, Covacu R, Lassmann H, Olsson T, Jagodic M. Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats. PLoS One. 2012;7(7):e39794. Epub 2012 Jul 16. PMID: 22815714. 
 追加の系統情報: