| 特性など: |
振戦が15日齢で認められ、約6カ月齢になると後肢弛緩性不全麻痺を呈するようになる（Rehm, 1982）。病理組織学的に中枢神経系の空胞変性と低髄鞘形成が確認される（Rehm, 1982, Kondo, 1991）。ポジショナルクローニングによりZIラットの脳におけるAtrn mRNA量が著しく少ないこと、zi遺伝子はAtrn遺伝子のイントロン12のスプライスドナーサイト内の8塩基対欠失であることが判明した（Kuramoto, 2001）。（Jun 19, 2009） |
| 参考文献: |
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