Reporter gene transgenic rats

GFP, DsRed, LacZ and other marker genes are important research tools for revealing biological processes.
Our repository has many of such reporter gene transgenic strains with ubiquitous or organ specific promoter.

Search reporter gene transgenic rats

 

* FAQ *

Which strains are frequently used?

A list of frequently used strains.
NBRP No Strain Name Background Strain Promoter Expression site Reporter Gene Expression Level
0235   SD-Tg(CAG-EGFP)4Osb  Slc:SDCAG ConstitutiveGFP ++
0273   W-Tg(CAG-GFP)184Ys  Crlj:WICAG ConstitutiveGFP ++
0277   W-Tg(Alb-DsRed2)34Jmsk  Crlj:WIAlb liver DsRed2 ++
0280   DA-Tg(CAG-lacZ)30Jmsk  DACAG ConstitutivelacZ ++
0282   W-Tg(CAG-DsRed2/GFP)15Jmsk  Crlj:WICAG ConstitutiveDsRed2/GFP ++
0283   W-Tg(CAG-cre)81Jmsk  Crlj:WICAG Constitutivecre  
0297   LEW-Tg(CAG-EGFP)1Ys  LEW/CrlCrljCAG ConstitutiveGFP ++++
0298   LEW-Tg(Gt(ROSA)26Sor-lacZ)44Jmsk  LEW/CrlCrljGt(ROSA)26Sor ConstitutivelacZ +++
0299   LEW-Tg(Gt(ROSA)26Sor-luc)11Jmsk  LEW/CrlCrljGt(ROSA)26Sor Constitutiveluciferase ++
0371   W-Tg(S100b-EGFP)Scell  Crlj:WI S100bastrocytes, adipocytes,
chondrocytes etc
GFP ++
0469   W-Tg(Gnrh1-EGFP)Nphy  Jla:Wistar Gnrh1GnRH neuron GFP ++
0470   W-Tg(CAG-EGFP)3Ys  Crlj:WICAG ConstitutiveGFP +++

 

How to select your strain?Marker strains

There are several points to select your strain.

  ・ background strain
  ・ promoter
  ・ reporter gene
  ・ preservation status
  ・ reference
…closed colony or inbred, etc
…organs expressing the reporter are different depending on the promoter
…detection method is different depending on the reporter gene
…if the strain were preserved as embryo, it would take about one year until send you animals
…the strain already reported, etc

NBRP-Rat dose NOT check the sites or the intensity of transgene expression. The information presented here is based on the information from the depositor or published papers.

We would recommend you to check their details, including whether or not the strain is suitable for your research.

 

What does strain name mean?

  example:  DA-Tg(CAG-lacZ)19Jmsk

  Tg denoting transgene
  rat strain DA carry the Tg(CAG-lacZ)19Jmsk transgene
  CAG: promoter, lacZ: reporter gene, 19: a line number, Jmsk: lab code

Please refer to below:
Rules and Guidelines for Nomenclature of Mouse and Rat Strains
Rules for Nomenclature of Genes, Genetic Markers, Alleles, and Mutations in Mouse and Rat